Author Archives: karen

How to increase heights in short populations such as the Philippines

Interactions between nutrition and various infections in developing countries are complex and analyses of the inter-relationships requires data from longitudinal studies spanning several years and a comprehensive framework facilitating the formulation of food and health policies. There

A natural transgene may help plants to adapt to local conditions

Transgenes are genes that have moved from a donor to a recipient organism via a process known as horizontal gene transfer (HGT), in the absence of sexual reproduction. The genetic modification of crop species involves the deliberate

Certain transcripts synthesized by RNA polymerase III in mammals became polyadenylation-competent

It has been known for 40 years that eukaryotic mRNA molecules contain a region of up to 250 adenine residues at the 3’ end. This poly(A) tail mediates mRNA nuclear export, translation, and protection from degradation in

Is the behaviour of the isotope polonium-210 conditioned by the acidity of the waters?

The Acid Mine Drainage (AMD) is a phenomenon that takes place when sulphide minerals are exposed to atmospheric conditions. In the presence of oxygen and humidity, the sulphides are oxidised releasing the elements contained in the rocks

Electrospun CH3MOF-5/PAN composite nanofibers for SPE of levonorgestrel and megestrol acetate

Electrospinning is a very simple , versatile and high – throughput method for generating continuous nanofibers from a wide range of materials including polymers , composites and ceramics with controllable diameters , compositions and morphologies. It was

Enrichment design accommodating the biomarker misclassification

Increased understanding of the mechanistic heterogeneity of diseases has brought us to the era of molecularly targeted therapies (MTAs) in clinical oncology. The MTAs block the growth of cancer cells by identifying and attacking specific biomarker pathways

Life on sulfur. Why we need complete genomes

The ability of bacteria to grow on inorganic compounds like sulfur was discovered by Russian microbiologist Sergey Winogradskij in 1888. First, he studied a sulfur bacterium of the Beggiatoaceae family to demonstrate that it can produce energy

Inventing an new flap for small to medium-sized defects of the knee

Coverage of soft tissue defects of the knee due to multiple operations, trauma and infection remains a surgical challenge. Often these defects are repaired using free tissue transfer. The aim of the current study was to find

Primary care doctor follow up of buckle fractures of the forearm

A buckle fracture of the distal radius (wrist bone) is a very minor fracture and the most common fracture in childhood. A “buckle” fracture occurs when there is a wrinkling of the outer edge of the bone

Treatment of preterm births with pregnancy hormone, human chorionic gonadotropin

Birth of infants between the 20th to 37th completed gestational weeks is considered preterm. They account for more infant deaths than from any other single cause. The incidence is about 9% in the U.S. and it is

Do plants have brains?

Many organisms have circadian clocks. These internal clocks play essential roles for predicting day-length or seasons, and they regulate behavior and hormonal secretion in animals, and also regulating flowering time and cell elongation in plants. In animals,

The undiagnosed, untreated key to restoring physical function and health in rheumatoid arthritis patients

Rheumatoid arthritis (RA) is characterised by adverse changes in body composition – specifically, reduced muscle mass (MM) and increased fat mass (FM). Indeed, when body composition is assessed (i.e. MM and FM are estimated), significant muscle loss

A new way for use of solar light in wastewater treatment

Acrylonitrile (CH2=CH-CN) is generally considered as hazardous pollutant since it is mutagenic, carcinogenic and teratogenic to human health. Traditional control technologies of acrylonitrile include adsorption and desorption, thermal and catalytic incineration at high temperatures and biotechnological abatement

Clinical depression predicts persistence of paranoia in clinical high-risk patients to psychosis

Pathways to both occurrence and persistence of paranoia and persecutory ideation have always been a topic of great interest in psychiatry research. Emotions, anxiety and depression in particular, have been in focus of this discussion. Wilhelm Griesinger

Training African health practitioners within Africa; expanding the skills pool

The African Paediatric Fellowship Programme (APFP) was established by the University of Cape Town (UCT) and the Red Cross War Memorial Children’s Hospital (RCWMCH) in 2007. The aim of the APFP is to create a network of

Cushing’s Syndrome: an update on current pharmacotherapy and future directions

Cortisol is an adrenal hormone essential for the maintenance of homeostasis, especially in response to stress. When cortisol levels are increased, this is defined as Cushing’s syndrome (CS). CS can be associated with increased morbidity, and when

Food and Nutrition cause liver and brain diseases with diabetes in the developing and developed world

In the world the consumption of a healthy diet is essential to prevent diseases such as obesity, diabetes and brain diseases. New discoveries in medicine indicate that a diet that is low in fat and carbohydrate lower

Can the developmental synchrony be affected by the mothers?

Biological synchrony is a ubiquitous yet highly diverse phenomenon, with examples as wide-ranging as applause among humans, migration of fish and birds, aggregation of insects, and mass flowering of bamboos. Developmental synchrony, resulting from reduced fluctuation in

Targeted exercise intervention for bradykinesia in Parkinson’s disease

Exercise has been used as an intervention for many diseases; however, to maximize the benefits of any exercise intervention there we must understand that exercise is not a blunt, unidimensional tool; but rather, a malleable prescriptive instrument

Computational systems biology in cancer brain metastasis

Cancer metastasis, especially cancer brain metastasis, is a complicated process representing the major cause for cancer-related deaths worldwide. A better understanding of the underlying mechanisms of such malignancies will enable us to develop more efficient therapeutic strategies.