Author Archives: Tigran Dadalyan

Complementary therapies can increase survival in cancer patients

It is well known that a large percentage of cancer patients use some form of complementary and alternative medicine (CAM), usually with the goal of improving quality of life, providing supportive care as well as  relieving pain

Metformin is a potential remedy for the treatment of Gaucher disease

Glycosphingolipids (GSLs) are amphipathic compounds consisting of oligosaccharides and hydrophobic chain of ceramide. They are ubiquitously distributed in the outer leaflet of the plasma membrane and believed to be involved in a large number of cellular processes,

Replacement of saturated with unsaturated fats had no impact on vascular function but beneficial effects on lipid biomarkers and blood pressure

Disease of the heart and blood vessels (referred to as cardiovascular disease (CVD)) is the primary cause of death worldwide. A key public health recommendation for reducing the risk of developing CVD is to lower our intake of

Employing more nurse practitioners can lower health care costs

We all want to have access to health care when we are not feeling well and we want to do so without breaking our budget.  However there is growing concern about the availability of care and the

Association of polymorphism gene with clinical variability in cystic fibrosis patients

Cystic fibrosis (CF) is an inherited disease, caused by a dysfunction (mutation) in the cystic fibrosis transmembrane conductance regulator (CFTR) gene. This disease affects a numerous organs particularly the lungs and digestive system. CF is characterized by

A new drug to prevent vomiting from cancer treatment

Vomiting after drug treatment for cancer used to be a major problem. However 2 different types of drugs were introduced which reduced this vomiting. The first was ondansetron which was very effective for the vomiting which occurred

Plant flavonoids prevent cancer progression through suppression of new blood vessel formation

Flavonoids are a sub-family of polyphenolic compounds. They are abundantly found in plants and known to have inhibitory properties in the initiation, promotion and progression of invasive cancers. Cancer progression is a complex process. It is mainly

An innovative method to increase access to surgery worldwide

One of the major health challenges facing almost two thirds of the world’s population is a lack of access to safe life-saving surgery. Picture a scenario where a loved one is involved in a terrifying accident and

Ability of four vitamin D assays to measure vitamin D2

Vitamin D, the sunshine hormone, is essential for healthy bones.   Vitamin D is found in two basic forms in nature—vitamin D3 which is made by skin exposed to sun rays (cholecaliferol), and vitamin D2 which is made

From the gut to the eye: commensal microbes as potential triggers of autoimmune uveitis

Autoimmune uveitis is a group of inflammatory diseases that affect the retina of the eye and related tissues and constitute a major cause of human blindness. It is believed that the disease is triggered by the activation

Biodiesel synthesis in response to individual short chain fatty acids during mixotrophic mode of microalgal cultivation

Growing concern over fuel crisis and global climate change has led to substantial investment and research into alternative fuel sources. In this prospect, photosynthetic organisms have huge potential for biofuels production in a carbon neutral way with

Slug transcription factor activates its own expression during epithelial to mesenchymal transition

Cancer is a highly aggressive and challenging disease. In several instances, symptoms are not evident until the disease progresses to an advanced stage and hence, it is amongst the leading causes of human mortality. Despite considerable attempts

Birth weight is not solely determined by genetic code

It is believed that genetic information carried by our DNA determines our metabolism and how we look. This is especially true for identical twins. The incidence of identical twins is around one in every 200 deliveries. Although

Small-molecule RETRA is effective against a fatal childhood cancer

The bone tumor Ewing’s sarcoma is one of the most aggressive cancers in childhood and adolescence. Before the era of chemotherapy, more than 90% of Ewing’s sarcoma patients succumbed to their disease. With the introduction of intensive

Bone marrow transplantation resets the clock in patients with Chronic Lymphocytic Leukemia

Chronic Lymphocytic Leukemia (CLL) accounts for about one third of all of leukemias. In the United States 15,000 patients are diagnosed with and 4,500 patients die of CLL every year.  CLL is a diverse disease. Some patients

Comparison of biological and cultural evolution

Biological evolution is a population-level process guided by selection, and it leads to an increase of the adaptation of the population for the environmental circumstances in which the population lives. Culture can be defined as the wholeness of

Rare and uncommon cancers

A rare cancer is one that occurs less than 6 times in 100,000 people and an uncommon cancer is found between 6 and 12 times in each 100,000 people. The problem with being rare is that there

Controlling self-assembly processes on 2-D surface

Supramolecular self-assembly on two-dimensional (2-D) surface is a powerful approach to construct functionalized surfaces. In a self-assembly process, molecules assemble via noncovalent interactions such as van der Waals or hydrogen bonding interactions, and form periodic nano structures.

Efficient tuning of carbon surface: Defect-enriched CNT

To face energy and environmental issues, the importance towards development of novel catalytic materials with clean and highly efficient feature is self-evident, since the catalysis is the cornerstone for chemical industries. The development of low-cost sustainable catalysts

Agreement between physician’s recommendation and fitness-to-drive decision in multiple sclerosis

Multiple sclerosis (MS) is a progressive disease of the central nervous system with potential debilitating effects on visual, motor and cognitive functions. These functions are essential for daily life activities, such as driving a car. Previous studies