Author Archives: Tigran Dadalyan

The portal venous system in liver cirrhosis: not yet a gray zone

Liver cirrhosis is a complex disease involving many systems, mainly located inside the abdominal cavity. The clinical diagnosis today is usually followed by laboratory, endoscopic, radiological examinations, among which the sectional imaging tools, ultrasound, computed tomography  and

Does physical functioning, emotional and behavioral problems differ in children with ADHD +ASD and ADHD?

ADHD and autism spectrum disorder (ASD) are two of the most common neurodevelopmental disorders, affecting approximately 5% and 1% of the population, respectively. Up to 79% of children with ASD and 50% of children with ADHD are

Treating primary cardiac angiosarcoma

Radiotherapy and chemotherapy are usually reserved for inoperable patients or given adjuvantly for those with residual tumor and/or metastatic disease. Elsayad and coworkers describe a novel treatment modality with adaptive radiotherapy using tumor-volume tracking in a 37-year-old

CML – where do we stand in 2015?

The progress with CML‐treatment continues at a rapid pace. Treatment of choice is targeted therapy with tyrosine kinase inhibitors (TKI). Five‐year survival ranges around 91% and 10‐year survival around 84% up from 11% with Busulfan 30 years ago. More

Computational study of optical and electronic properties of metal-decorated Graphene

The computational methods for studying the various properties of nanomaterials like Graphene, have become extremely popular these days. Thanks to the ever increasing processor speeds. These methods include Density functional theory ( DFT ) and Time dependent density

Treating prostate cancer with immunotherapy

Cancer immunotherapy induces the immune system to recognize and destroy cancer cells. These therapies can work through a number of ways but two of the most researched methods are therapeutic cancer vaccines and immune checkpoint inhibitors. Therapeutic

Engineering social justice into self-driving vehicles?

Self-driving vehicles will soon be a central part of our transportation system. Their introduction promises several benefits, including improved traffic safety, mitigated fuel consumption, congestion, and pollution, and enhanced mobility for persons unable to drive. The introduction

Gold “bowtie” coming into reality on two-dimensional MoS2 surface

“Bowtie’’, which is a type of necktie, is very popular in our daily life. In some formal meetings or parties, bowtie is the normal choice to make you look good. Actually, this kind of bowtie structures of

Lipofuscin, lipofuscin-like pigments and autofluorescence

This paper provides a syntethic overview on lipofuscin and lipofuscin-like substances, with particlar reference to their biological significance as well as to their cellular origin and pathophysiological role. Special emphasis is also placed on the mutual relationships between

What does the PROMISE trial mean for cardiac CT?

Current guidelines recommend functional testing (FT) such as exercise tests or nuclear tests (with very high radiation exposures) to identify those patients who have chest pain that may benefit from stents or bypass surgery.  Unfortunately, a vast

Case study of a successful metals recovery project

As we continue to invent, manufacture, and consume countless numbers and types of consumer goods, we need an increasing study supply of raw materials, especially metals. Although the earth’s metal resources are finite, we continue to mine

Changes in anti-predator behaviour of prey after large predator declines

Large carnivores are suffering severe declines worldwide due to their vulnerability to habitat loss, emerging diseases and persecution. Their loss has been attributed to changes in the abundance and behaviour of other species, including small mammals and

Compounds from Australian Eucalypts: the next wonder-drug for cancer?

If there is one tree that every Australian can relate to, then it would be the none other than the Eucalypt. No wonder they are considered as the only trees that have the power to unite the

Forecasting malaria using environmental and clinical predictors

In 1911, Christophers developed an early-warning system for malaria epidemics in Punjab based on rainfall, fever-related deaths and wheat prices. Since that initial system, researchers and practitioners have continued to search for determinants of spatial and temporal

Controlling gene expression in bacteria

Gene expression enables cells to implement the instructions encoded within the genes on their DNA. Being able to control gene expression is therefore key to this most fundamental biological process, so determining cell fate and behaviour. Cells

Analysis of volatile organic compounds

Entombed victims under the ruins of collapsed buildings, because of natural or man-made disasters, patiently wait for help in order to be identified, detected, safely extricated and finally saved by urban search rescue (USAR) teams. This is

A platform for measuring carbon and nitrogen levels of metabolism-related genes in durum wheat

Multiple lines of evidence confirm that as a result of human activities the greenhouse gas emissions are rising more rapidly than predicted and, consequently, the world is warming more quickly. Global climate change threatens for food security

Adolescents with gender dysphoria

As soon as young children acquire language most will start understanding that they are a boy or a girl and they will increasingly feel and behave in accordance with  the gender assigned to them at birth. Some

Our sense of length difference between two successive time intervals depends on which interval is held constant

How sharp is our sense of time? This is often investigated in terms of the smallest difference in the duration of two time intervals that can be detected with a given accuracy, usually 75%. This difference threshold

Core predictors of ‘hassles’ among patients with multimorbidity in primary care

A major problem in current primary care is that services are set up for single long term conditions, whereas many older patients have more than one.  Studies conducted through interviews only suggest that patients experience ‘hassles’ in