Author Archives: Tigran Dadalyan
Chromatin remodeling regulates multiple liver functions
Liver is a one of the largest tissues that has the ability to regenerate itself upon stimulation. The liver also performs a variety of complex functions which support body homeostasis including detoxification and providing essential molecules to
Current perceptions with regard to the causes of shoulder impingement syndrome
One of the most common musculoskeletal complaints of patients seeking medical advice is shoulder pain, with shoulder impingement syndrome being the most commonly diagnosed shoulder disorder. Modern advances in anatomy, biomechanics, and research have gone some way
The resilient pituitary gland: What happens when the pituitary gland has to be cut during surgery?
The pituitary gland is considered to be the “master endocrine gland”. It is a pea-sized structure located at the base of the brain, important in controlling growth and development and the functioning of the other endocrine glands.
Genomic characteristics of miscarriage copy number variants
Miscarriage is a stressful event for couples and finding the cause is critical for closure and also future reproductive planning. Gains and losses of genetic material in the miscarriage are one of the possible causes of miscarriage
Cigarette smoke enhances the release of proteins that modulates pro-thrombotic midiators in vascular cells
About 6 million people die for use or exposure to cigarette smoke; indeed smoking is the most important evitable cause of death in the developed countries, and it is a major risk factors for cardiovascular diseases. Chronic
Leukemia cells rely on vesicles from neighboring stromal cells to resist common cancer treatments
Leukemia is a cancer of white blood cells that occurs in both children and adults. Strides have been made in curing most types of leukemia. However, acute myeloid leukemia (AML) continues to resist the same treatment strategies.
Rapid prototyping to explain the biology of seahorse tails
Rapid prototyping employs the use of modern engineering tools, such as computer modeling and 3D-printing, to build physical models of new product design concepts. Applying similar techniques, our team of biologists and engineers built two 3D-printed models
Single-cell-culture experiment made easier for researchers
Single-cell-culture experiment is widely used for biological researches concerning cell heterogeneity. This experiment although straightforward to performed by the limiting dilution method with manual pipetting and cell culture well plates, is time consuming and not cost-effective. To
Metallothionein, oxidative stress and trace metals in gills of liver of fish species
Kuwait Bay is important area that is influenced by the local municipal and industrial discharges. Therefore, two types of local fish from were studies, yellow finned seabream which is pelagic fish swim between the surface and the
A novel perspective on schizophrenic-like symptoms
One of the key questions in neuroscience involves understanding how the brain processes cognitive functions – like learning new information, making adaptive decisions, and engaging in social interactions with others. We know that these activities occur across
Dendritic cells: Implication of molecular mechanism in allergic reaction to betalactam antibiotic
Adverse drug reactions are a serious health problem, accounting for 3% of revenue and becoming the fourth leading cause of death in the United States. These reactions include allergic reactions caused by specific immunological mechanisms, which are
CD64 as a sepsis marker
Sepsis is the most common cause of mortality in critically ill patients worldwide. Despite with huge costs, it is difficult to treat sepsis. Early diagnosis sepsis and timely treatment are vital to improving outcomes and lightening the
Conserved nitrogen-regulated network modules in rice
The goal of this research work is to transfer “network knowledge” from a data-rich model plant, Arabidopsis, to rice, to enhance the identification of nitrogen gene networks in a data-poor crop. Our working example for this study
Advanced green antibacterial materials made by mussel-inspired chemistry
Since ancient times, silver and its salts have universally been employed as antibacterial agents for the treatment of infections, burns and chronic wounds in curative and preventive health care, because of their extraordinary inhibitory and bactericidal properties
Increased stress hormone exposure can be beneficial
Under challenging circumstances, such as predator exposure or lack of food, animals naturally secrete stress hormones. Production, secretion and release into the bloodstream of these hormones is tightly regulated by the Hypothalamic-Pituitary-Adrenal axis (the stress axis), a
Marine oily wastewater treatment: process simulation and control using soft computing approaches
The chronic discharge of oily wastewater, mainly including bilge water, offshore produced water and ballast water, has been referred to as a major contributor to marine oil pollution. Although gravity – based treatment techniques (e.g., hydrocyclone and
Cost compared to effects of food and micronutrient supplementation in pregnancy for rural Bangladeshi women
When under nutrition affects pregnant women it many leave long lasting consequences on the newborn baby. Even though over nutrition in the form of overweight and obesity is now sweeping the world, in low-income countries under nutrition
Assessment of the influence of traffic-related particles in dust
Dust particles present in our daily lives consist of a mixture of materials from different sources, such as soils, traffic-related particles, pavement particles, etc. Due to their low particle size, dust particles can be easily re-suspended and
Oxygen-transfer performance of a new, very low-volume membrane oxygenator
During heart surgery, an external system (extracorporeal circulation) is often needed to replace the normal function of the heart and lungs to ensure blood circulation to the brain and all other organs. One key element of this
From milliseconds to lifetimes: dynamic behavior of transcription factors in gene networks
When living organisms are exposed to a sudden change in the environment, many genes are turned on in an organized manner to enable the organism to cope and respond to the changing environment. This coordinated genome-wide response
