Author Archives: Tigran Dadalyan

Gaining insight in biological hydrogen production by computational approaches

Hydrogen is one of the most important raw materials for the chemical industry and has an undisputed future importance as an environmentally friendly fuel. At present, 96% of the 500 billion m3 of hydrogen gas that is

Fully human anti-CAIX antibodies for RCC immunotherapy

Globally, there are roughly 270,000 new cases and 116,000 deaths attributed to kidney cancer occur each year. More than 90% of kidney neoplasms are classified as renal cell carcinoma (RCC), which accounts for 3% of all adult

Utilizing inkjet printing for low-cost glucose monitoring

Diabetes is a disease affecting more and more people across the world every year. In low-income countries, this growth is most detrimental since they lack the healthcare infrastructure necessary to deal the growing problem. Work is being

Fluid flow dynamics in a Nuclear Magnetic Resonance system

Nuclear Magnetic Resonance (NMR) is a very powerful analysis method employed in biology and chemistry. It helps us to gain information about the molecular structure of a wide range of molecules. For example food production companies employ

A slipped-alignment of rhodamine dyes results in pink-to-blue color change

Color originates from absorption and reflection of visible light. The reason that a molecule can absorb a certain color of light is the interaction between molecular electrons and incident light. If the electronic state of a molecule

The influence of pollution on bone premature aging: the case of the fishbone

Bone is one of the most sophisticated biological structures developed by nature, its major constituent is a calcium phosphate mineral that is similar, in composition and structure, to minerals within the apatite group which are naturally formed

Granule formation in pancreatic acinar cells

The pancreas is an important gland organ within the digestive and endocrine system of vertebrates. It is both an endocrine and exocrine gland. The endocrine part produces several important hormones such as insulin which are released in

Allylic oxidation of steroidal olefins

The goal of steroid chemistry is to chemically modify naturally occurring steroids in a way that will alter their biological activity to the benefit of mankind, livestock, and plants.  This process can be achieved by adding a

Potential for therapeutic intervention in lung diseases

The major function of the lung is to enable ambient oxygen uptake (essential for life) and eliminate carbon dioxide (a waste byproduct of metabolism) from the body. Surfactant protein A (SP-A), is a protein found in the

Hybrid mimics, a new strategy for increased food production

The growth of the world’s population is presenting a major challenge to agricultural industries to produce enough food for all people.  We have been carrying out research which could provide a component of the needed food supply

Effects of untreated and treated oilfield-produced water on seed germination of sunflower

Currently, about 70% of water consumption is dedicated to agricultural irrigation and the growing use of bioenergy tends to aggravate water scarcity. The oilfield produced water is produced in large quantities in onshore and offshore oil exploitation.

Molecular giants detected in agarose gels

Lipopolysaccharides (LPS), which are the major biological macromolecules of the surface from Gram-negative bacteria (fig. A), are of huge interest in medicine. Large amounts of LPS in the bloodstream cause diverse pathophysiological effects, causing thousands of deaths

Fear of anxiety and the brain response to threatening stimuli in panic disorder

Panic attacks are periods of very sudden intense fear, accompanied by bodily or cognitive symptoms (such as heart palpitations, dizziness, shortness of breath, or feelings of unreality) that can last from 10 minutes to hours and are

Studying the interactions that trap cells in circulation

Healthy blood stem cells and invasive tumor cells use similar mechanisms to exit the circulatory system and penetrate other tissues. Cell migration is a multi-step process in which a number of adhesion molecules find their partners and

Inhibitors of gastric acid secretion and gastric cancer

The highly acidic gastric juice is an efficient killer of swallowed microorganisms. This is an important function which is reflected in the tight regulation of gastric acidity involving both nerves and hormones (blood born messengers). The most

Air pollution forecasting is required for citizens’ protection in urban environments

Air pollution is one of the most harmful factors posing threat to human health, worldwide. Of particular concern in urban environments are particulate matter (PM), especially fine (PM2.5) and ultrafine (PM1) fractions, ground-level ozone (O3), and nitrogen

The use of co-crystal technology for stabilizing energetic materials

The use of co-crystallizations is emerging as a new avenue for modifying the solid-state properties of a wide range of high-value chemicals, such as agrochemicals, pharmaceutics, dyes, and nutraceuticals, in such a way that certain physical properties