Tag Archives: chronic
What treatment is really medically and economically desirable for chronic hepatitis C patients with treatment failure after 8-week glecaprevir/pibrentasvir in Japan?
Currently, direct-acting agent (DAA) therapies have high efficacy and safety and are the main strategy to eliminate hepatitis C virus (HCV) worldwide. Some DAA therapies are also effective for HCV-infected patients who have experienced prior DAA failure.
Vitamin D is an important hormone in growth and bone metabolism. Vitamin D deficiency is highly prevalent worldwide and causes growth retardation and rickets in children and osteomalacia in adults. However, the role of vitamin D deficiency
Lymphocytes are white blood cells that are central in the immune response to foreign microorganisms. Like all cells, lymphocytes have a membrane, a lipid bilayer, that envelops the content of the cell. Proteins attached to the cell
Pancreas is very important organ in our body and it is located in the abdomen behind the stomach. Pancreas is a gland and secrets some chemicals called enzymes. It is a leaf like structure and divided in
Using artificial intelligence to understand irritable bowel syndrome, chronic fatigue syndrome and fibromyalgia syndrome
Modern medicine is based on the concept of disease. Each disease has its own unique and specific pathophysiology – meaning that each disease has a biological fault that defines that disease and only that disease. Functional disorders
Across the world, about one in six people suffer from chronic stomach symptoms, including feeling very full and uncomfortable or bloated after eating, being unable to finish a normal sized meal and experiencing after meals frequent stomach
Serotonin and noradrenaline reuptake inhibitor (SNRI) for chronic musculoskeletal pain may be a red herring?
Dysfunction in the central serotonin and noradrenaline systems cause not only depression but also increased pain sensitivity. Many animal studies indicated that lumbar-intrathecal administration of serotonin and noradrenaline reuptake inhibitor (SNRI) could ameliorate the pain sensitivity which
Chronic intestinal pseudo-obstruction (CIPO) is a rare disorder that affects the intestinal tract of children and adults. It is a chronic and devastating disease that has significant morbidity and mortality. CIPO is characterized by severe and disabling
Kinases are enzymes that phosphorylate proteins, leading to their activation within cells. Over 500 kinases have now been identified in human cells and they activate many processes in the cells, including the production of inflammatory mediators. Kinases
Chronic wounds are a frequent finding in clinical practice and one of the problems with high impact on social health, affecting mainly the elderly people with chronic diseases (diabetes, nutritional abnormalities, cardiovascular diseases, chronic motor deficit and
The common denominator of different types of cancers is an ever expanding clone that originates from a single cell. In acute leukemia the clonal expansion may be very rapid and the clone double its size sometimes within
Once thought to be affecting only affluent countries, cardiovascular diseases, diabetes, obesity and other life-style related diseases (collectively referred to as non-communicable diseases or NCD) are now the leading cause of death and disability also in developing