Tag Archives: heart

PDE2 is a potential new target for the treatment of cardiac hypertrophy

Heart failure is one of the leading causes of death in the Western World today. It typically involves a deficiency of the heart to provide sufficient blood flow and/or blood pressure to meet the requirements of the

Maternal diabetes negatively affects the development of embryonic heart

Diabetes in pregnancy may negatively affect the developing fetus, neonate, and child. Poorly controlled maternal hyperglycemia before conception and during the first trimester is associated with an increased rate of major birth defects and spontaneous abortion. Cardiovascular

Fat content surrounding your heart may cause your arrhythmia to recur

Epicardial adipose tissue (EAT) is a metabolically active fat depot surrounding the heart. It is located between the outer wall of myocardium and the visceral pericardium. Its proximity to cardiac structures (i.e. vessels, myocardium) and its shared

Excess oxygen worsens actual oxygen supply to the heart muscle in pigs

The use of supplemental oxygen in acute medical care is perceived beneficial by many health care professionals. However, current guidelines limit the excess use of oxygen after successful resuscitation following cardiac arrest. This recommendation is based on

Is digoxin safe?

Digoxin is a medication commonly used in patients with heart disease. It is extracted from the foxglove plant and was first described in 1785. During the last few centuries it has become an established treatment in patients

A gentle look at the heart

Coronary artery disease is one of the major causes of death in the Western population, mainly because of the potential risk of a heart attack. The latter often occurs out of the blue and the only chance

Cardiac atrial appendage stem cells: bright cells for a bright future for patients with ischemic heart disease

Ischemic heart disease is still one of the major causes of global morbidity and mortality. Although significant improvements in medical and surgical treatments have been accomplished over the last few decades, these are still not able to

Characterisation of the human epicardium in the developing heart

The vertebrate heart is composed of three cell layers: an inner layer lining the heart chambers (atria and ventricles), the endocardium; an intermediate muscle layer, the myocardium; and an outer layer that envelops the myocardium, the epicardium.

Newborn pulse oximetry screening is not just for heart defects

Measuring the arterial oxygen content (saturation) of the blood is easily done by pulse oximetry. In newborn infants a probe emitting and absorbing light is put on the hand or foot (or booth) and a reliable result

Serum potassium decline associated with increased mortality in acute heart failure

Acute heart failure (HF) is the most important reason for hospitalization in the United States and Europe. It is associated with high morbidity and mortality, most conspicuously in the first months after discharge. As HF progresses, and