Tag Archives: inhibitors

Inhibitors of intracellular enzymes for treatment of multiple sclerosis

The protein kinase inhibitor imatinib

Lymphocytes are white blood cells that are central in the immune response to foreign microorganisms. Like all cells, lymphocytes have a membrane, a lipid bilayer, that envelops the content of the cell. Proteins attached to the cell

Activation by inhibition

Phosphorylation of proteins is one of the most important mechanisms through which protein function is quickly and reversibly regulated. Prototypically, an extracellular ligand binds to its cognate receptor(s) on the surface of a target cell, leading to

GlyT2 inhibitors: Getting the balance right

In the central nervous system, signals are sent through brain pathways using neurotransmitters, the chemical messengers of our brain. The strength and duration of these messages are governed by the concentration of neurotransmitters in the synapses between