Tag Archives: pancreatic cancer

Metformin improves pancreatic cancer and lymphoma outcomes in DM2 patients

AoS. Metformin improves pancreatic cancer and lymphoma outcomes in DM2 patients

Type 2 diabetics are at increased risk of cancer in part because of increased insulin in the blood from insulin resistance. Insulin and its related growth factor IGF-1 can stimulate cell growth through the Ras-Raf-MEK-ERK or the

Tumor regression in a high-mortality mouse pancreatic cancer (xenograft) model with aminosteroid RM-581

Chemical representation of aminosteroid derivative. Atlas of Science

Pancreatic cancer is classified as a high-mortality cancer with a five-year relative survival rate of only 9%. Although most cancer type survival rates have improved over the past decades, pancreatic cancer morbidity has been stable, which illustrates

Treatment of elderly patients with pancreatic cancer

Our publication is about elderly patients’ treatment evaluation for pancreatic cancer in the United States. This is a Surveillance, Epidemiology, and End Results (SEER)-Medicare analysis of patients above age of 65 who have Medicare and were treated

Opium use increases the chance of pancreas cancer in a large population-based study

Pancreas cancer is a common cancer with few treatment options and as a result is associated with considerably reduced chances of survival for the patients. Several factors such as obesity, diabetes, and smoking (including smokeless and other

Biomarker panel for detecting early pancreatic cancer

Pancreatic ductal adenocarcinoma (PDAC), the most prevalent type of pancreatic cancer, is the fourth leading cause of cancer-related deaths in the USA. Most of the PDAC patients are diagnosed at an advanced stage of disease and their

Pancreatic cancer stem cells: fatty acid synthesis and mevalonate pathways are implicated in their survival

Pancreatic ductal adenocarcinoma (PDAC) is an aggressive malignancy with a high metastatic potential. The disease is the fourth leading cause of cancer-related deaths in the USA, and is projected to be the second one by 2030, due

Positron Emission Tomography can visualize pancreatic cancer tumor changes during chemotherapy and predict longer survival

Pancreatic cancer is one of the most deadly cancer types. Only 20% of patients live beyond 1 year after diagnosis because of the aggressive nature of this disease and ineffective treatments. Therefore it is crucial to recognize

The molecular analysis of tumor cells in pancreatic tissue – searching for a needle in a haystack

In cancer research usually the tumor cell specific abnormalities are of interest: gene mutations, production of abnormal proteins, production of abnormal quantity of proteins, tumor cells treatment response. But the molecular analysis of pancreatic tumor samples poses

Pancreatic cancer and innovative treatment: the seeming paradox to block the immune response

Pancreatic cancer (PC) is the 5th leading cause of cancer‐related death in the developed world with more than 260,000 annual deaths worldwide and with a dismal 5‐year survival (5%). The lethality of pancreatic cancer is due to

Granule formation in pancreatic acinar cells

The pancreas is an important gland organ within the digestive and endocrine system of vertebrates. It is both an endocrine and exocrine gland. The endocrine part produces several important hormones such as insulin which are released in

Surgery for pancreatic head cancer

Pancreaticoduodenectomy (PD) offers the only chance of long-term survival for patients with pancreatic head cancer. The procedure involves removing the pancreatic head together with the duodenum, gallbladder and most of the common extra hepatic bile duct (Fig.

Using nanotechnology to outsmart pancreatic cancer

Cancer is a versatile disease and makes use of complex cellular signaling networks to defend itself against a host of treatments. Pancreatic cancer in particular has proven challenging with tenacious resistance to DNA-damaging chemoradiation. Malignant cells disobey