Tag Archives: systemic sclerosis

Circulating fibrocytes as possible new target of abatacept effect in systemic sclerosis patients

Circulating fibrocytes as possible new target. AoS

Systemic sclerosis (SSc) is an autoimmune connective tissue disease characterized by microvascular and immune response alterations followed by a progressive fibrosis, which is the consequence of an excessive production and deposition of extracellular matrix molecules, primarily fibronectin

Nailfold microangiopathy in dermatomyositis and systemic sclerosis: what is different in long term follow-up?

Nailfold videocapillaroscopic pictures. AoS

Dermatomyositis (DM) is a chronic inflammatory disorder involving mainly the skin and muscles. Systemic Sclerosis (SSc) is an autoimmune rheumatic disease of unknown etiology characterized by vascular alterations and progressive tissue fibrosis of multiple organs. Peripheral microangiopathy

Capillary number in the “late” pattern correlates with the progression of organ involvement in systemic sclerosis

Systemic Sclerosis (SSc) is an autoimmune rheumatic disease characterized by vascular alterations and tissue fibrosis of multiple organs. Vascular structural alterations are detected early and seem to play an important role in SSc pathogenesis. Microvascular damage is

A capillaroscopy based method to help prediction of Systemic Sclerosis onset

Systemic Sclerosis (SSc) is a rare systemic disease, characterized by immune system alterations and diffused microvascular disruption, followed by fibrosis of skin and internal organs, and Raynaud’s phenomenon (RP) is often the first clinical manifestation of the

Updates on the pathophysiology of systemic sclerosis

Systemic sclerosis (SSc) is a heterogeneous connective tissue disease with autoimmune component, inflammation, and progressive fibrosis of conjunctive tissues of the skin and internal organs. Lung involvements are a major cause of concern as pulmonary fibrosis and