Daily Archives: November 11, 2020

Upstream open reading frames (uORFs) as translational regulators in human disease

AoS. Upstream open reading frames (uORFs) as translational regulators in human disease

The messenger RNA (mRNA) translation process is a key step of gene expression, whose regulation allows the cell to rapidly change protein synthesis in a spatio-temporal manner in response to different stimuli. Translation comprises four steps –