Author Archives: Tigran Dadalyan
The variegated world of poly-ubiquitin chains
Proteins share with living beings the events of birth, life and death. They are ‘born’ when information contained in the DNA is translated into an amino acid chain and live their life in their natural environments (i.e.
Neurons share the same destiny irrespective of their location: A closer look at PP-MS pathogenesis
Multiple sclerosis (MS) is a disease of the central nervous system, caused by the reaction of immune cells against myelin, a membrane that surrounds the axons of nerve cells. MS is characterized by the presence of inflammatory
The application of biosensors for meat quality analysis
To meet the demands of growing meat consumption in recent years, animal farming tended to increase meatiness. The rise of meatiness was not in concordance with the improvement of the meat quality. The quality of meat is
How actinomycin binds to DNA and exerts its mechanism of action
In this remarkably simple and profound article — recently appearing in the March issue of the Journal of Structural and Functional Genomics — Henry M. Sobell describes his theory for the existence of “premeltons” in DNA —
How cancer begins and how to prevent it
Cancer is a problem of chemical carcinogenesis. This means that chemicals are involved in the processes leading to cancer. Knowledge of how certain molecules work is, therefore, essential for understanding how cancer begins. The chemicals that cause
A new test to select more effective treatments for lung cancer
Sadly, the majority of patients with Lung Cancers who cannot be treated by surgery to remove their tumour, die within a few years. Small numbers are beginning to benefit from chemotherapies which target very specific types of
Less is more for staging vaginal cancer
Criteria for predicting the survival of women with vaginal cancer has been established by physician specialists trained in treating gynecologic cancers in the United States and around the world. The current 5-year overall survival is approximately 74%
The management of horses during fireworks in New Zealand
The negative effects of fireworks on companion animals have been reported, but little has been documented on the impact on horses. Horse anxiety was commonly associated with fireworks, and 26% of owners reported horses injuries as a
Association between periodontal disease and erectile dysfunction
Chronic periodontitis is a common inflammatory condition of infectious origin that affects the supporting periodontal tissues (including cementum, gingiva, periodontal ligament and alveolar bone) resulting in bone loss and, if left untreated, in tooth loss. In the
Are the physicochemical properties and bacteriological composition of composts linked?
Compost is the product of composting, which is a biological process to valorize and recycle a variety of organic wastes. Given the benefits of composting numerous industrial units have been commercializing this type of product. The parameters
Methodology of interdisciplinary and nursing studies based on Islamic documents
Every methodology is supposed to pursue the philosophy in its target society. Therefore, it is necessary to Muslims society generate knowledge through methods recognized in Islamic sciences. Moreover, expanding the boundaries of knowledge can help scholars discover
Team collaborative behaviours unveiled during laparoscopic simulation
Laparoscopic surgery, a type of minimally invasive surgery performed in the abdominal area, has become a leading advance in surgery over the past decades. During the procedure, small incisions are made for placing the scope and surgical
Recovering from addiction: Do peer-delivered services help?
New research indicates that addiction to alcohol and drugs is a chronic condition. For many, recovery from addiction is often a lengthy process that requires ongoing management and support. Yet the traditional approach to addiction provides intensive
Psoriasis, more than a skin disease? The involvement of gut microbes
Psoriasis, is a chronic inflammatory skin disease with a high prevalence, of which the exact cause is unknown. Genetic, immunologic and environmental factors all are involved. Psoriasis and Inflammatory Bowel Disease, including Crohn’s Disease and Ulcerative Colitis,
Vitamins and minerals in control of serious diseases?
We all know that vitamins and minerals are important, but why? The amino acid L-tryptophan is “essential” for mammals, and it must be obtained in the form of food. L-tryptophan can be utilized for protein synthesis, and
From crime scene to crime lab: potential interactions between blood detection methods
Crime scene investigators and forensic scientists at the crime laboratories both utilize rapid, presumptive tests to determine the likelihood of the presence of blood. At the crime scene, investigators commonly utilize Bluestar® or Luminol to produce a
Einstein and the measurement problem: Is he right again?
In quantum mechanics there exists an unresolved and much debated foundational issue known as the ‘measurement problem’, of how and where one goes from the microscopic quantum world to the macroscopic classical world when an abstract entity
Fish are exposed to hundreds of pharmaceuticals. How to identify drugs that pose the greatest aquatic risk?
After consumption, human and veterinary drugs or their breakdown products end up in streams and rivers via wastewater effluent discharges into water bodies. Since this is a continuous process, aquatic animals are chronically (low concentration, long-term) being
The constant cost of short-term memory loss
When we try to make sense of what someone says to us we maintain a record of this information in memory. Many psychologists think that humans evolved a ‘verbal short-term memory’ system for this purpose, and we
Survival analysis using Excel: learn it, use it and improve your work
Questions about disease prognosis and patient survival are of central importance in everyday hematology/oncology clinical practice. If a person working as a practicing clinician would like to evaluate his/her own work or check if some factor affects
