Tag Archives: cancer therapy
A molecular passport authorizes intracellular travel for a potential cancer therapy antibody
Allosteric degraders of EGFR leading to cancer cell detachment-promoted death

Epidermal growth factor receptor (EGFR) allosteric tyrosine kinase inhibitors (TKIs) have emerged as a therapeutic option for overcoming drug resistance in cancer. We have developed furfuryl derivatives of 4-allyl-5-[2-(4-alkoxyphenyl)-quinolin-4-yl]-4H-1,2,4-triazole-3-thiol and have shown that these compounds bind to