Tag Archives: cancer

A way to a man’s (or women’s) kidney is through the stomach

Kidney cancer can be difficult to diagnose. A biopsy may be needed. Kidney biopsy is usually taken by passing a needle from the outside of the patient into the kidney. The needle is passed from the patient’s

Breast cancer in elderly – does guideline adherent treatment really matter?

It is well known that breast cancer is currently the most common female cancer. Advances in diagnostics and treatment continuosly improve the long term outcome. To establish a new agent or therapy a randomised study with inclusion

The protective role of estrogens in prostate cancer and its relationship with the SCF/c-KIT system

Prostate Cancer (PCa) is the most common oncological disorder in men worldwide, mainly affecting individuals over the age of 50. Therefore, the population aging and the improved expectancy of life have been contributing to the increased incidence

The surgeon general should say that indoor tanning causes skin cancer

It is a widely accepted fact that smoking causes lung cancer. This dates back to 1964, when the Surgeon General’s report clearly acknowledged this link. Fifty years later, the Acting Surgeon General, Dr. Lushniak, was asked to

Using university-sponsored debit cards for indoor tanning services: an update

Numerous studies have established a link between indoor tanning bed use and increased risk for skin cancer.  In fact, those who begin using tanning beds before the age of 35 increase their risk for melanoma, the deadliest

Spinal tumors in children: a rare disease

Tumors of the Central Nervous System (CNS) are one of the first causes of morbidity and mortality in children in developed countries. Among them, spinal tumors are estimated to account for less than 10% of the cases,

Putting mammalian target of rapamycin on track

Mammalian target of rapamycin (mTOR) is the target protein of rapamycin, a bacterial metabolite in Streptomyces hygroscopicus primarily found in the soil sample from Easter Island in South America thirty years ago. Since mTOR was discovered in

From palliative to curative treatment – a case of stage IV mucinous colorectal cancer

Colorectal cancer (CRC) is the third most common cancer in the world and in Sweden, next to breast cancer and prostate cancer. In Sweden, more than 6,000 people are diagnosed with CRC and around 2800 people die

The thymus: a small organ with a mighty big function

The thymus lies in the chest behind the breastbone and above the heart. Relatively large in infancy, it increases in size until puberty and thereafter shrinks to only a few grams in old age. It consists of

How can cancer cells use hydrogen peroxide to strive?

Hydrogen peroxide (H2O2) is a well-known antiseptic used in our homes since the 1920s. But did you know that our cells produce this molecule and that at low concentrations H2O2 instructs our cells to do different things,

“Chemobrain” prior to cancer treatment? The cause is probably cancer-related post-traumatic stress

Cancer patients often complain about deficits of attention, memory, and other basic cognitive functions, which considerably impact on their lives. Long time, these problems were simply attributed to side effects of chemotherapy and have therefore been termed

New function for the well-known lipids

Angiogenesis is the new blood vessels formation in adult tissues which share some similarities to growth of blood vessels during development called vasculogenesis. It is estimated that growth of any tissue to the sizes above 2-3 mm3

A novel reovirus mutant: toward the next generation of viruses for cancer treatment?

In the last decade or so, it has been realized that viruses are not only foes to fight, but possible therapeutics against diseases such as cancer. Most of these so-called oncolytic viruses are engineered to acquire desirable

Using tumor DNA to refine lung cancer staging and treatment

The treatment of non-small cell lung cancer (NSCLC) is guided by disease stage as assessed by clinical and pathologic criteria.  Clinical tumor stage is determined by imaging including computed tomography (CT) scans, magnetic resonance imaging (MRI), positron

How to spot a sick cell?

Mass spectrometry (MS) is a technique used to measure the mass of molecules. Chemists extensively use this method to confirm that they have made the right molecule by comparing the mass of the actual product with the

More reasons to appreciate the Golden Spice “saffron”

Cancer remains a leading cause of morbidity and death worldwide. What is even worse is that the number of new cancer cases is projected to massive increase which would probably make it the first cause of death

High prevalence of undertreated cardiovascular disease in patients diagnosed with cancer

Heart disease and cancer are the most common causes of death in the United States. They often have the same risk factors (for example, smoking, advancing age, obesity). Heart disease can worsen outcomes after cancer therapy and

A growing epidemic: HPV-related oropharyngeal carcinoma

The incidence of Human Papillomavirus(HPV)related oropharyngeal cancer has increased by epidemic proportions (225%) over the past 30 years. If it continues to increase at the current rate, the incidence of HPVrelated oropharyngeal cancer will be even greater

Dissecting how cells communicate to prevent cancer relapse

Protein kinases are a class of enzymes that are responsible for the transfer of phosphates onto other proteins. These phosphate groups, although small, can change the behaviour of the protein itself, or the behaviour of those it

Learning from evolution to target cancer with combinatorial strategies

Chemotherapy is the most prominently used therapy for many cancers yet it effects multiple and, in many cases, unknown targets. Of the most modern advancements in cancer treatment is the targeting of single key gene products, for