Tag Archives: mRNA
Blocking miR-212/132 in T cells is a potential therapy for treating colitis
Inflammatory bowel diseases (IBD), which include Crohn’s disease and ulcerative colitis, is thought to be caused by aberrant immune response to host intestinal microbiota, leading inflammation in gastrointestinal tract. The symptoms such as diarrhea, rectal bleeding, anemia,
Virus containing mealybug DNA kills mealybug
One way of self-regulating protein synthesis by animals is suppression of the relevant messenger RNA (mRNA); molecules that translate into amino acids and act as building blocks for protein. The mechanism, called RNA interference (RNAi), works by
Helicase and ribosome share a common mechanism of nucleic acid unwinding
In the cell DNA is present in the duplex form and many messenger RNAs (mRNAs) can form duplex structures. To access the genetic information (represented by nucleotides or codons) on the single-stranded (ss) nucleic acids (NA) by
Potential for therapeutic intervention in lung diseases
The major function of the lung is to enable ambient oxygen uptake (essential for life) and eliminate carbon dioxide (a waste byproduct of metabolism) from the body. Surfactant protein A (SP-A), is a protein found in the
What is necessary to be prion-like domain?
Prions are infectious proteins that can assume various conformations, including amyloid fibrils that can serve as a matrix and “infect” other proteins both within and between the cells and between organisms. However, it was observed that yeast
A small RNA, microRNA-155, “micromanages” inflammation and renewal of neurons in the brain
The immune system is like a silent army, protecting the body from enemy viruses and bacteria. Inflammation is part of this response, acting to eliminate pathogens and initiate tissue repair. Most of the time, our immune systems
A better understanding of cell division by combining mathematical modeling and experimentation
The cell division cycle is the process by which a growing cell replicates its genome and partitions the two copies of each chromosome to two daughter cells at division. It is of utmost importance to the perpetuation
