Monthly Archives: March 2017
Personality and alcohol use disorders outcome
The main objective of Alcohol Use Disorders (AUD) treatment is to give up alcohol drinking for as long as possible, and, secondly, to reduce physical harm by drinking less alcohol. However, there are two important problems which
Mapping the magnetic domain imaging for nano-magnetic films using novel MFM tips
MFM is an extended measurement function of the tapping-mode scanning and lift-mode controlling modes of atomic force microscopy (AFM), where the magnetic domain image is obtained by detection of magnetic force gradient changes between a magnetic tip
A 10 km intense run increases the number of cells in blood responsible for vascular repair
Exercise can cause a wide number of things to happen within our body. Our heart rate increases, our blood vessels dilate, we oxidise more fat and carbohydrate, and we can actively stimulate the repair of our own
4-PBA improves lithium-induced diuresis by attenuating ER stress
The Kidney regulates body water and sodium balance. The kidney produces approximately 180L of primary glomerular filtrate per day in a healthy adult. The majority of this filtrate is reabsorbed in the segments of kidney through water
Tay Sachs in South Italy
Tay Sachs disease (TSD) is an autosomal recessive neurological disorder characterized by significant deficiency of lysosomal enzyme β-Hexosaminidase A and subsequent intralysosomal accumulation of GM2 ganglioside. The classical TSD occurs in early infancy with psychomotor retardation, blindness,
Identification of a new T cell regulator
T-cell receptor (TCR) signaling is mediated by the activation of protein-tyrosine kinases such as p56lck and ZAP-70. In mature T-cells, CD4 and CD8 molecules bind to p56lck which then phosphorylates the intracellular immune-receptor tyrosine-based activation motifs (ITAM)
Does subjecting health students to stressful scenarios better prepare them for real world practice?
Simulation is an education and training technique that allows students to practice in safe environments that replicate substantial aspects of the real world in a fully interactive fashion. Simulation is often used to train undergraduates as it
Determination of the size of folding nuclei of fibrils formed from Aβ(1-40) peptide
One of the most important models for studying amyloid fibril formation is the Aβ peptide, aggregates of which form plaques in the course of Alzheimer`s disease. Formation of Aβ aggregates goes through the nucleation mechanism with exponential
3rd International Conference and Expo on Drug Discovery & Designing. Vienna, Austria. October 02-04, 2017
Conference Series has taken an initiation to conduct international conference and Expo on Drug Discovery & Designing workshops worldwide . From last 3 years Conference Series has been conducting Drug Discovery & Designing conferences in major continents
A novel method for the preparation of 18F-labeled α-SCF3 carbonyl compounds
As fluorine-18 (18F) is the most commonly used radioisotope in positron emission tomography (PET), significant efforts have been devoted to the exploration of efficient methods for the incorporation of 18F into small and biological molecules. However, the
Next generation sequencing, a new gold standard for clinical gene panel testing
The adaption of the Next Generation Sequencing ( NGS ) technology to clinical laboratories has revolutionized the molecular diagnostics by reducing the costs and increasing the throughput. Clinical use of NGS enables simultaneous testing of multiple genes
Oral anticoagulants and renal failure: The mystery yet unsolved
The optimal utilization of novel oral anticoagulants (NOACs) in patients with renal failure represents an urgent, unmet, and yet unsolved need with regard to the choice of agents, duration of treatment, and potential dose/regimen adjustment. Lack of
Human chorionic gonadotrophin induces ovarian follicle growth in pregnant sows
Fertility of female pigs is often significantly depressed during the summer and early autumn, an effect referred to as seasonal infertility. Manifestations of seasonal infertility can include reduced pregnancy rates and, less often, smaller litter sizes. These
Atomic structures of telomerase shed light into the mechanism of telomere replication
Telomeres comprise the six nucleotide repeats at the end of eukaryotic chromosomes and they are essential for the faithful replication and protection of our genome. Significant telomere attrition forces the cells to enter a dormant state to
The importance of clinical endpoints in lymphoma
Lymphomas, or neoplasms of the lymphoid system, include a broad array of cancers. The least aggressive, often called indolent, lymphomas (the most frequent of which is follicular lymphoma, FL) are characterized by their incurability. At the same
Sick already? Job loss makes it even worse
There are good reasons to expect job loss to deteriorate health. It reduces available income and social contacts, might affect daily routines and social identity. Obviously, it seems unrealistic to assume health consequences of job loss to
Uncovering the diversity of a rich insect family in Colombia, the case of the genus Notiospathius
To understand a phenomenon, we usually start by looking at the number and type of parts that compose that subject; we like to know the anatomy of a system in order to move into its functionality. The
Epigenetics and multiple sclerosis
Genetic studies have long been trying to describe the etiopathology of human diseases. Even though the cutting-edge approaches like whole human genome sequencing and genome wide association studies have largely improved our apprehension, there are numerous questions
Hiding under sea bed: a new species of sand crab Jonas kalpakkamensis is discovered
The common edible crabs which we often encounter in land, sea and freshwater bodies mostly belong to a group classified as brachyuran crabs. They constitute a third of the commercial value of Indian seafood. There are about
Metal-organic frameworks (MOFs): a new leak proof electrolyte for alkaline fuel cell
Everincreasing energy demand of world and pollution associated with fossil fuels , has demanded an urgent need to develop alternate clean energy systems. Fuel cells are the promising energy technology which converts chemical energy into electricity through
