Yearly Archives: 2017
Strollers and carriers cause average of two injuries every hour in the U.S.
The Center for Injury Research and Policy of the Research Institute at Nationwide Children’s Hospital published research about children getting injured from strollers and carriers in Academic Pediatrics in August 2016. Parents use these products every day
Variation in fecundity among species and its evolutionary consequences
Predicting the evolutionary trajectories of living species give us the chance to develop informed management policies and preserve species at the brink of extinction. Also, the possibility to understand the consequences of climate change and of introduced,
Electromembrane extraction and spectrophotometric determination of As(V) in water samples
Arsenic is an important environmental element because of its high toxicity at the level of parts per billion. According to World Health Organization (WHO) guideline on drinking water quality, the maximum permitted concentration of arsenic in drinking
New discovered biomarkers as useful molecular targets in testicular germ cell tumors
Testicular germ cell tumors (TGCTs) are histologically classified as seminomas and non-seminomas according to the international classification of oncological diseases. Both these tumors display an invasive phenotype and are believed to be derived from a common ancestor,
The slippery head of the fastest fish
The swordfish (Xiphias gladius) is reputedly the fastest swimmer on Earth. Its concave head and iconic sword are unique characteristics, but how they contribute to its speed is still unknown. Our paper reports the discovery of a
Dysfunction of cellular analgesic control in neuropathic pain
Neuropathic pain in small-fiber neuropathy was traditionally considered a consequence of injury to nociceptors and sensitization. An alternative view has also been put forward: there may be a loss of the neuronal analgesic control system, paralleling the
Threats from antifouling priority pollutants in the Adriatic sea
To ensure the preservation of public health and ecosystems it is essential to reach a good chemical status of surface water bodies and groundwater. To this end, such waters should comply with the Environmental Quality Standards (EQS)
The promiscuous mineralocorticoid receptor
Hormones and nerves are the key communication systems in the human body. Nerves are like a fixed-line telephone network, capable of very fast messaging: think of the pianist’s fingers playing the Minute Waltz. Hormones are like radio,
Drugs from the sea: complex structures to fight a complex problem of resistance in cancer
It is well known that incidence of cancer cases figures among the leading causes of morbidity and mortality. Most of disseminated cancers share the common feature of not responding to anticancer drugs. This phenomenon is known as
Algae and moulds: Causative agents of respiratory tract disease in horses?
This investigation identifies the alga Prototheca and the mould Pithomyces chartarum as rare causes of upper respiratory tract inflammation in horses. More frequently, upper respiratory tract disease in horses is caused by viral and bacterial infections. Patients:
Microneedle patch for fast and sustained pain relief
The occurrence of pain is very common in routine life and during invasive clinical procedures, such as injections, surgeries etc. which is the usually treated using painkiller and local anesthetics in form of oral dosage forms, creams,
Lung cancer imaging before surgery and the role of brain MRI
Lung cancer kills more people each year than any other cancer worldwide. The best chance at curing the cancer is with surgery, however not all lung cancers can be taken out. Surgeons use a variety of imaging
Atelocollagen-conjugated miR-520d-5p is effective dramatically in therapy-resistant undifferentiated cancers
We have previously shown that hsa-miR-520d-5p can convert cancer cells into induced pluripotent stem cells (iPSCs) or mesenchymal stem cells (MSCs) via the demethylation and consequent upregulation of TP53 in vivo. We have also reported that miR-520d-5p
Mechanism of the tumor suppressive properties of glycodelin
Malignant growth in cancer is characterized by loss of cell differentiation, uncontrolled proliferation and resistance to apoptosis. In some cases it is possible to revert malignant cells back to normal. However, this process is not very well
Lipid modified natural RNA
tRNA is an integral part of the protein translation process. It translates the genetic code from mRNA to make the corresponding protein. The process of protein translation requires a well-defined structure of specific tRNA and its ability
The Fracture Liaison Service. A standardized order set towards efficient management of fragility fractures with minor expenses
Over more than a decade, the secondary fracture prevention strategy has been the heart of osteoporosis-related fracture management studies. Management programs have oscillated between low and high levels of intensity of intervention(s); sensitization through letters or pamphlets,
Stopping the spread of diarrheal disease through the environment
More than half a million children die every year from diarrheal diseases. Most of these diseases are caused by pathogens, or “germs”. In my paper Environmental Transmission of Diarrheal Pathogens in Low and Middle Income Countries published
Small dense LDL, sub-clinical atherosclerosis and psoriatic arthritis
Psoriatic arthritis (PsA) is a chronic arthropathy associated with psoriasis, marked by an axial and/or peripheral joint involvement and high cardiovascular. Several large studies confirmed the relationship of small dense LDL (sd-LDL) with coronary events. Although some
Acute stroke in 3 brain territories suggests cancer
Over the past several decades cancer has increased to rival heart disease as the leading cause of death in the United States. Non-infectious endocarditis and cancer-associated hypercoagulation (C-AH) have both been suggested as a source of stroke
Artemisia annua leaves improved solubility of antimalarial drug, artemisinin
Artemisia annua L., also known as Sweet Annie, is a Chinese medicinal herb that produces the important antimalarial drug, artemisinin. Artemisinin is the most powerful antimalarial ever discovered and its derivatives are the main component of artemisinin
