Category Archives: Research
Oligodendrocyte Tau’s failed quest for microtubules results in myelin decrease and falling
Oligodendrocytes make a good-sized myelin that surrounds axons and allows humans to walk and see. In contrast, when axons do not get enough myelin, axonal function is incapacitated, with resulting deficits in cognition, behavior, and in the
A better understanding of cell division by combining mathematical modeling and experimentation
The cell division cycle is the process by which a growing cell replicates its genome and partitions the two copies of each chromosome to two daughter cells at division. It is of utmost importance to the perpetuation
Sensitivity to explosion of chemicals estimated using only a hand held calculator
The ability to predict the explosivity of energetic materials on the basis of their molecular structure would be of utmost interest for the design of explosives and propellants, to develop safe handling practices in the field and
Cold denaturation
Most proteins can be thought like beady chains which form compact well-ordered coils whose surface protects the greasy-like interior from the contact with water molecules. We are studying what are the forces which keep the coil compact.
Glutathione: a molecular whistleblower for Alzheimer’s disease
Alzheimer’s disease: Neurons in select pockets of the brain begin to die off, slowly and incrementally erasing an individual’s memory and eroding their individuality. It is a devastating disease, one that affects more than 36 million individuals
New drugs for cancer treatment
Cancer is a major cause of death and more than 1 million people in the United States are diagnosed with cancer each year. Finding more effective methods to treat cancer remains a challenge, and researchers are working
The CORAL software as spyglass to detect “coral reefs” in ocean of nanotechnologies
There are many messages about nanomaterials. There are the both bad and good facts. It is clear these substances are fastly penetrate into many fields of everyday life, such as food, cosmetics, pharmaceutics, electronics, etc. Therefore one
Some need to reduce blood pressure medication in hot weather
Many people take medication for blood pressure control. But there have been many reports suggesting (i) that dosage should be reduced in hot weather and (ii) a need for long-term individual studies. This paper presents a case
Metallic iron for environmental remediation: ending a myth
Iron corrosion is widely known as a destructive process. However, several useful applications of this process are known. Three examples are: consumption of humidity in food packaging, H2S removal from biogas and water treatment. Water treatment by
Cell division drives collective motion in cell monolayers
Cell division is essential to morphogenesis, tissue spreading, and tumor invasion. In particular, the hallmark of tumor invasion is the ability of cancerous cells to divide in extreme numbers. Our findings on the effect of cell division
Obesity causes lung dysfunction and breathing troubles by increased cysteinyl leukotrienes pathway
Increased body weight is a chronic health problem which has emanated from the globalized food market and dietary habit. This has led to the different types of ailments which occur in obese individual simultaneously and referred to
A functional defect of unconventional suppressor T-lymphocytes might lead to disease progression in lupus autoimmune patients
A healthy immune system discriminates between pathogenic invaders that have to be eliminated, and the body’s own tissues that have to be protected. Central to this role are immune cells called lymphocytes. B-lymphocytes are particularly important, because
Resveratrol is a potential remedy for the treatment of pancreatic fibrosis
The pancreas serves as both endocrine and exocrine glands in a human body in order to help food digestion and blood glucose regulation. In fact, more than 90% of the pancreatic mass comprises the exocrine cells which
Depression and dementia among American Indian and Alaska native elders
In the United States when talking about health care we tend to refer to national or state programs as uniform programs that are accessed by all U.S. citizens. . But there are groups that have a separate,
A potentially lethal condition that may occur in psychiatric patients
Antipsychotic drugs are commonly prescribed in patients with various psychiatric illnesses (e.g. psychosis, schizophrenia, aggressive behavior, etc.). A neurological emergency may arise characterized by muscle rigidity and damage, increased body temperature and cardio-respiratory system instability in patients
The first medical school in America
The founders of first American medical school in Philadelphia, John Morgan and William Shippen, Jr, had received a fine medical education at the University of Edinburgh. As students, they discussed the need for such training in the
High-throughput, motility-based sorting of microswimmers for gene discovery
Organisms’ motility varies with genotype, disease progression, drug treatment, aging, and environmental conditions and can serve as a useful metric to access drug effectuality, to identify drug resistant strains, and, more generally, various genotypes. In 1974, Sidney
Why do older people get so much kidney disease?
To celebrate Sir William Osler’s 70th Birthday on July 12th 1919 his pupils and co-workers contributed scientific articles that were collected and published. One of these articles, by William Councilman pathologist-in-chief at Peter Bent Brigham Hospital, noted
Recursion. How did it evolve?
“It was a dark and stormy night. The crew said to the captain, “Captain, tell us a story.” The captain said to the crew, ‘It was a dark and stormy night …” -A story from popular culture
Neurocysticercosis: a mayor public health problem
Neurocysticercosis (NCC) is the most frequent parasitic disease of the central nervous system, and it occurs when the larvae of the tapeworm Taenia solium infects the central nervous system. This disease is endemic in most developing countries
