Category Archives: Research
Malrotation, a congenital condition that causes intestinal obstruction in infants, unusually presented in a 92 year old man
Malrotation is a rare condition that occurs when there is a problem during development of the gastrointestinal tract. The development of the intestines is a complex process that occurs during the 5th to 12th week of gestation.
Rapid monitoring of bacterial growth and antibiotic susceptibility with quantum semiconductor biochips
Public Health authorities sound the alarm over the increasing bacterial resistance to antibiotics and project a dark picture back to the pre-antibiotic era. One avenue of solutions proposed is to identify the spectrum of susceptibility to antibiotics
Modeling mammary gland development: understanding the role of cell types and hormonal signaling in the terminal end bud
The mammary gland is an organ that develops almost completely after birth. It has been extensively studied and its development is well-characterized. As such, it provides an excellent model system to study the details of mammalian organ
Chemistry from the kitchen to the primordial soup
The Maillard reaction, also known as the non-enzymatic browning reaction, is a series of chemical interactions that occur in food that are subjected to thermal treatment such as roasting, frying, grilling, and cooking. The Maillard reaction is
Does bioenvironment affect the ionization of drugs?
The ionization is one of the most important parameters that must be taken into account when predicting the pharmacological behavior of drugs. The ionization profile directly affects water solubility which has significant influence on drug bioavailability and
Disparities resulting from variations in regional donor supply and liver transplant tourism
In the United States, the Organ Procurement and Transplantation Network (OPTN) develops national policies that determine how donated organs are collected, matched, and distributed with candidates on the transplantation waitlist. Currently, the nation is divided into 11
Crosstalk between arbuscular mycorrhizal fungi and host plants under drought stress
Drought stress is detrimental to plant growth and development. Nevertheless, plants have evolved mechanisms to cope with drought stress at cellular, tissue, and whole-plant levels. Plant physiological responses to drought stress are initiated and sustained by signal
Coffee for the relief of symptoms of methotrexate intolerance among patients with rheumatoid arthritis
Patients with rheumatoid arthritis (RA) and some of the other systemic autoimmune rheumatic diseases are commonly prescribed methotrexate (MTX) at the dose of < 25-30 mg/week. Depending upon the patient’s condition and the dosage prescribed, some patients
Blood pressure charts for pediatrics
Blood pressure screening is essential throughout life. Adult blood pressure assessments have static thresholds of 140/90 for hypertension and 90/60 for hypotension but screening blood pressure in children is more complicated. As children grow, normal blood pressure
Accessory proteins RTP1S and SNMP1 support the expression of the insect co-receptor Orco in mammalian culture cells
The study of insect olfaction has been a hot topic in research for long time. No wonder! Small tiny fruit flies (Drosophila melanogaster) navigate through all your house and are able to detect that one orange in
Sexuality and predisposition to altered states of consciousness
In 1974, Tellegen and Atkinson proposed that ‘absorption’ is a core personality trait that consists of the degree to which one becomes so attentionally absorbed in sensations and imagination that there is an alteration of the sense
The proteins and their mRNAs may be located in different areas of the embryos
All proteins are synthesized in a cell in polysomes (polyribosomes) on the template (mRNA). That is why in molecular embryology, by tacit consent, a presence or absence of the specific mRNA in the cell indicates the presence
The grass is green and the nanosilver now too
Advances in nanoscience have been accompanied by improvements in capabilities to deliver compositional and morphological control of matter. Syntheses of Nanocrystals (NCs), where material science elements are addressed with organic chemistry precision techniques, are specially challenging and
The enemy of my enemy is my friend?
Rice is the most important staple crop for two billion people in the world. However, the production system where rice is grown submerged in water (paddy fields) is under threat due to changing weather conditions. Due to
Females with anorexia nervosa in Singapore
Pressure to be thin can be exerted by various sources both external and internal. Sociocultural pressures include the showcase of gracile models and advertisements for diet products and slimming programmes in magazines and on television, criticisms about
Behavior of Staphylococcus epidermidis in biosynthesis of silver and cadmium sulfide nanoparticles
Microorganism biosynthesizes nanoparticles using its enzymes and biomolecules which can act as reducing and capping agents. In fact, the nanoparticle is a produce of detoxification pathways. These pathways neutralize the toxicity of metal ions and trap them
Motor nerve terminals with fast downregulation of Syt1 are more vulnerable in Spinal Muscular Atrophy
Spinal Muscular Atrophy (SMA) is the most frequent genetic cause of infant mortality. It is caused by mutations or loss of the SMN1 gene, which codifies for the Survival of Motor Neuron (SMN) protein. SMN has an
Does thyroid hormone deficiency in fetal life have adverse effects on cardiovascular system during adulthood?
Proper development of fetus depends on its genetics as well as the hormonal, metabolic, and nutritional environment provided by the mother. Deficiency of thyroid hormones (THs) at birth is considered as congenital hypothyroidism and the prevalence of
In the pursuit of personalized medicine; New technologies to study the gut microbiome
Humans have a symbiotic relationship with microbes that reside in and on our bodies. The human digestive tract contains as many as 1014 of bacterial cells, making it one of the densest and most diverse microbial communities
