Tag Archives: cancer
Cancer risk in opposite-sex and same-sex twins
Twin pregnancies are characterized by simultaneous development of two fetuses that share the womb. An interest in opposite-sex (OS) twins, twin pairs consisting of one male and one female, comes from animal studies that showed that exposure
How does bladder chemotherapy given before surgery change bladder cancer cells?
It is estimated that there will be 74,000 new cases of bladder cancer diagnosed in the United States and approximately 16,000 deaths due to bladder cancer in 2015 alone, according to statistics from the American Cancer Society.
Helpful tool for the characterization of cancer
Follicular lymphoma is a sort of blood cancer and among the most frequent subtypes of indolent (painless) lymphomas. Most patients are diagnosed very late, when the illness is in an advanced stage. The origins of the tumor
A novel method of stool DNA analysis for colorectal cancer diagnosis
Colorectal cancer (CRC) is one of the most frequent malignant diseases worldwide, with a high rate of mortality. The detection of precancerous and early-stage CRC is central to improve prognosis and the survival rate of patients. Currently,
Fluorescent micro-RNA for cancer diagnostics
Biomarkers are indicators of biological states or conditions and can therefore provide important information about diseases such as cancer. In clinical diagnostics biomarkers are most often proteins or nucleic acids such as DNA or RNA. Biomarkers that
New drugs for cancer treatment
Cancer is a major cause of death and more than 1 million people in the United States are diagnosed with cancer each year. Finding more effective methods to treat cancer remains a challenge, and researchers are working
Protein expression is useful to screen high risk patients for cancer
Endometrial cancer is the most common type of uterine cancer in the United States. The American Cancer Society estimates 54,870 newly diagnosed endometrial cancer cases and 10,170 deaths caused by endometrial cancer in 2015. Most patients (~80%) have a subtype called
Dragon fruit-like multifunctional probe for cancer precision theranostics
Along with the rapid rhythm of human lives, more and more fatal diseases have been surprisingly invading public health. Health is the greatest wealth, health is not equal to everything, but lose health will lose everything. Aside
Mitochondrial ROS and cancer drug resistance
The repetitive and continuous circle of resistance to anti-cancer agents was a primary focus of the above-titled articles recently published in Pharmacological Research. Gaining a basic understanding of why so many (possibly all) drugs currently available against
Breast cancer cells change and adapt during disease progression
A diagnosis of breast cancer usually includes characterisation of the breast cancer cells: determining if the tumour cells have hormone receptors and other proteins which will help to decide the best treatment options for the patient. This
A reproductive technology to reduce cancer risk
Preimplantation Genetic Diagnosis (PGD) is a type of assisted reproductive technology (ART) allowing individuals/ couples to choose which fertilized embryos, created through in vitro fertilization (IVF), are implanted into a woman’s uterus for further gestation. Since its
A key molecule for embryonic bone development is dysregulated in cancer
Bone is an endocrine organ with important biological functions. The skeleton produces hormones, such as FGF23 and osteocalcin, which regulate an extensive list of normal functions. Some of these functions include glucose metabolism, male fertility, blood cell
Using nanotechnology to outsmart pancreatic cancer
Cancer is a versatile disease and makes use of complex cellular signaling networks to defend itself against a host of treatments. Pancreatic cancer in particular has proven challenging with tenacious resistance to DNA-damaging chemoradiation. Malignant cells disobey
Rare breast tumor cells in lymph nodes are enough to impact on cancer cure
Early detection of breast cancer leads to essential cure of the vast majority of patients, through surgery and associated therapies. However, severe outcomes can be observed even among disease cases currently categorized as low-risk. Approximately 15% of
Regucalcin may prevent the development of prostate age-related pathologies such as prostate cancer
Regucalcin (RGN) is a protein with a multifunctional role, which regulates the basic biological processes determining cell fate. RGN actions have been implicated in the control of intracellular calcium levels, oxidative stress, cell metabolism, cell death and
Gene therapy not just counseling for your denim obsession
Imagine a world where one size does not fit all, wait that’s the world we live in now. So why is the treatment you get under the “one size fits all” umbrella, we are all different, right?
The potential in your pond
First described over 300 years ago, Euglena gracilis, is a single celled algae found in puddles and ponds around the world. This little organism is finding uses from foods to fuels and is even scheduled to be
A novel protein called nischarin
Nischarin is a large protein that is present in the nucleus and cytoplasm of cells. So far, diseases associated with the NISCH gene include hypertension, dry mouth, morphine dependence, depression, anxiety, thick heart walls, congestive heart failure,
Combining different antibody flavors to improve cancer therapy
Our immune system is specialized at identifying ‘foreign intruders’ (pathogens) or virus-infected cells inside the human body. This can be achieved by antibodies (immunoglobulins) that circulate in our body and are able to bind targets with high
Doctors, look up! Lack of eye contact reduces trust
Trust between breast cancer patients and their oncologist is crucial for good quality breast cancer care. It is associated with beneficial outcomes, such as a decrease in patients’ fear and better adherence. Patients’ trust was earlier shown
