Tag Archives: cancer
Outcomes of Influenza infections in hematopoietic cell transplant recipients
Influenza infection causes mild disease in most cases and severe complications in very few cases. The severity of influenza infection depends mainly on the type of influenza virus and the status of the patient’s immune system. Since
What if a surgically removed neck lymph node turns out to be cancer?
A rising epidemic in the United States is throat cancer, specifically a tumor called squamous cell carcinoma, induced by the human papilloma virus (HPV). Approximately 12,000 cases occur each year and the number is increasing. In this
Direct monitoring of the interaction between ROS and cerium dioxide nanoparticles in living cells
Swallowing the pill we don’t know whether it comes to the target, destroys the harmful objects (microbes, viruses, cancer cells) and/or whether it works correctly at the center of the inflammation. Let’s imagine that each grain of
Fluorescent carbon dots integrated hydrogels for lung cancer therapy
Cancer is considered as one of the leading cause of death worldwide. Due to the ever changing lifestyle of the modern society, the incidence of cancer is on the rise. Lung cancer is the most frequently diagnosed
Is our immune system mistaking tumours for foetuses?
Tumours are abnormal growths of tissue where cells produced by the body get out of control and divide at a rapid and unregulated pace. And – when you think about it – embryos too are masses of
Polyfunctional T cells induced potent anti-tumor efficacy
Adoptive T cell therapy is a form of cancer immunotherapy using T cells to target cancer cells. In adoptive T cell therapy, white blood cells are collected from cancer patients, T cells (CD4+ and CD8+ cells) within
The youth hormone DHEA in the treatment of liver cancer: die another way
Hepatocellular carcinoma (HCC) is a common form of malignant liver tumor and one of the leading causes of death all over the world. As for other types of cancer, many drugs have been developed and tested with
Improving nature’s own communication system to fight cancer
Our bodies are composed of trillions of different cells, which communicate with each other in order to keep us healthy. There are several ways in which messages can be sent back and forth between cells. One of
Animal-free platforms for the efficient and accurate prediction of kidney toxicity in humans
Tens of thousands of chemicals are used in food, cosmetics and consumer products. In addition, humans are exposed to drugs and environmental toxicants. Safety testing based on animals is too slow and too costly for screening the
A promising novel drug for breast cancer
The reason cancer is so difficult to treat is that cancer cells are our own cells running wild, which means that they generally do not make any protein or other molecule that normal cells don’t make. This
Heat shock protein as a novel druggable target in angiogenesis?
Angiogenesis is a physiological process that involves formation of new blood vessels from pre-existing vessels for efficiently providing oxygen and nutrients during growth and development, as well as during wound healing. Under pathological conditions, angiogenesis is regulated
Screening breast MRI in patients with personal history of breast cancer
This study looked at patients who had a personal history of breast cancer diagnosed at a premenopausal age to see if having screening breast MRI provided a benefit to the patient. Patients with a personal history of
How safe are we handling cytotoxics in academic laboratories in the UK?
Cytotoxics between practice and research Cytotoxics, mainly used in cancer treatment, are defined as agents that are toxic to living cells. Therefore, their handling needs to be carefully monitored in order to protect the user. The latter
Three dimensional quality assurance protocol for thoracic and genitourinary radiation therapy
After cancer diagnosis one treatment option is the use of external radiation. As the radiation traverses the patient it deposits most of its energy in the tumor, which causes irreparable damage to the cancer cells. One type
Treatment holidays for patients with metastatic kidney cancer
Targeted therapy is the standard treatment of patients with metastatic cancer of the kidney. The best current therapies target the tumour vasculature thereby blocking the access of the tumour to nutrients and limiting possibility of spreading to
Emergency department presentation predicts poor outcomes after meningioma removal
A meningioma is one of the most common forms of a brain tumor. Unlike many other types of brain tumors, meningiomas are typically associated with relatively favorable outcomes even when they require surgical treatment. In the past
Type of breast cancer provides clues to genetic susceptibility
Breast cancer is a common disease affecting 1 in 11 women in the UK but like many common cancers incidence increases with increasing age. Only 1 in 1,700 women younger than 30 and 1 in 228 women
Ultrasensitive detection and glycan analysis of a prostate cancer biomarker
In recent years we have seen an increased frequency of diagnosed prostate cancer (PCa) cases accompanied with an enhanced mortality worldwide. Symptoms of an early-stage PCa can be mild or even absent, thus there is an urgent
Colorectal anastomotic leakage: an ongoing mystery
Whenever people are diagnosed with an intestinal disease such as Crohn, Colitis or colorectal cancer, they might need to undergo surgery to remove the affected part of the intestine. During such surgery, the remaining parts of the
Renal cell carcinoma: can we identify patients with advanced disease?
Kidney cancer is among the 10 most common cancers in both men and women with approximately 61,560 new cases and 14,080 deaths from this disease expected in 2015. Clear cell renal cell carcinoma (ccRCC) is the most
