Tag Archives: cholesterol
There are thought to be good and bad types of cholesterol. High-density lipoprotein cholesterol (HDL-C) is thought to be a good type of cholesterol because it is believed to remove bad types of cholesterol from blood vessel
Cholesterol is the most abundant lipid of the mammalian plasma membrane. It is well known that cholesterol influences membrane biophysical properties and regulates the activity of multiple types of ion channels, including K+ channels. The reported mechanisms
The amyloid hypothesis maintains that the pathogenesis of Alzheimer’s disease (AD) is driven by the production and accumulation of amyloid-β (Aβ) peptides in the brain. Consequently, many therapeutic strategies to reduce Aβ production have been examined. However,
Breast cancer is the most common cancer in women and, despite significant progress in diagnosis and treatments, incidence has been steadily increasing in the last 40 years. Approximately 70% of breast cancers are characterised by the expression
Atherosclerotic plaques that clog major arteries lead to heart attack and stroke because of the loss of the local blood supply to the heart or to brain tissues. It is also increasingly recognized today that formation and
Cardiovascular disease (heart attack and stroke) is the leading cause of death in the United States. Prescription cholesterol-lowering medications have been shown to lower the risks for heart attacks and stroke. In fact, roughly 28% of Americans
Low density lipoprotein (LDL) cholesterol or the “bad cholesterol” is an established measure of cardiovascular risk. LDL particles interact with the lining of the blood vessel and contribute to cholesterol loading in the arterial wall. Continued buildup
Food and Nutrition cause liver and brain diseases with diabetes in the developing and developed world
In the world the consumption of a healthy diet is essential to prevent diseases such as obesity, diabetes and brain diseases. New discoveries in medicine indicate that a diet that is low in fat and carbohydrate lower
Lipoproteins are complex particles that are responsible for transporting the water insoluble molecule, cholesterol, through the blood stream. Cholesterol is transported from the liver to peripheral tissues. Excess cholesterol in low-density lipoprotein (LDL) is deposited in the
Modulation of bad cholesterol: what happens when patients with kidney disease receive omega-3-fatty acids?
Just as oil cannot dissolve in water, so cannot fat dissolve in blood. In order for our bodies to transport cholesterol, which is made of fat (lipids), within our bloodstreams something is needed to carry it around.
Dementia is a clinical manifestation of Alzheimer’s disease, dementia with Lewy bodies and is seen in a high proportion of late stage Parkinson’s disease patients. The symptoms are associated with degeneration of synapses, the structures by which
According to the World Health Organization, coronary heart disease is a major cause of death worldwide. In 2008, 17.3 million people died from heart disease, and this number is expected to rise further, reaching an estimated of
The presence of activated PI3K-AKT is a major obstacle to successful chemotherapies. Since PI3K-AKT is activated in many healthy tissues, chemical inhibitors of PI3K-AKT inevitably have many unwanted side effects. By using a cholesterol-targeting drug called beta-cyclodextrin