Tag Archives: enzyme

Enzyme-based computing systems: The half-adder and half-subtractor

Have we ever stopped to think what would happen if the silicon based computers that we have come to rely on reach the peak of their development?  Many scientists who work in the field of unconventional computing

Truncated INH-NAD adduct, an active intermediate in the action of Isoniazid (INH) against InhA enzyme in tuberculosis

Tuberculosis (TB) remains as an important infectious disease, caused by Mycobacterium tuberculosis (MTB) which is responsible for around 1.5 million deaths and 9.6 million new cases annually. Isoniazid (INH), a bactericidal compound used as a first-line drug

Understanding how enzyme injection for Dupuytren’s disease works

The fascia of the hand is a thin layer of connective tissue that wraps around the muscles, tendons, and neurovascular constitutions in the palm of the hand, providing structural support and integrity. The palmar and digital fascia

Ribose hydroxyl group summary

We usually think of enzymes – the molecules that drive all the reactions in our cells – as being proteins, but many scientists believe that the earliest enzymes may have been made of RNA. RNA, which is

How do chaperones save protein folding?

Protein folding both in vitro and in vivo goes via formation of intermediate states. These “molten globule”-like states fluctuate, expose their hydrophobic sites and therefore easily aggregate. This retards or even inhibits formation of protein native structures,

A novel reovirus mutant: toward the next generation of viruses for cancer treatment?

In the last decade or so, it has been realized that viruses are not only foes to fight, but possible therapeutics against diseases such as cancer. Most of these so-called oncolytic viruses are engineered to acquire desirable

Pre-treatment is important in the utilisation of food waste for the production of high value products

Proper disposal of food industry waste is a problem that developed as well as developing economies face alike. Conversion of food waste is a pioneering idea which can lead to huge financial gains while ensuring a healthy

Janus subcompartmentalized microreactors

When we are sick and have to take medicine, the first thing we do, is reading the package leaflet. We want to know the potential side effects of the drug. Sometimes the side effect of one drug

A versatile oxygenase family

Enzymes catalyze important biological processes throughout all kingdoms of life. One large and highly versatile enzyme family possesses a three-dimensional structure containing a double-stranded beta-helix (or jellyroll) protein fold that typically has a 2-histidine-1-carboxylate amino acid motif