Daily Archives: December 28, 2015

Liver X receptor beta, the link between thyroid hormone regulation and the browning of white fat

Everyone agrees that when our intake of sugar, fat and protein exceeds the body’s need for nutrition, excess is stored as fat. Fat in the form of white adipocytes is the body’s reserve of energy, which is

A combination therapy to induce apoptosis in difficult-to-treat cancer cells

The presence of activated PI3K-AKT is a major obstacle to successful chemotherapies. Since PI3K-AKT is activated in many healthy tissues, chemical inhibitors of PI3K-AKT inevitably have many unwanted side effects. By using a cholesterol-targeting drug called beta-cyclodextrin

A new approach to measure and evaluate inhibitory activity against protein glycation during heating

Glycation is the addition of a sugar moiety into a protein molecule occurring during Maillard reaction. It takes place both endogenously in the body and exogenously in food products. So-called advanced glycation end products (AGEs), lead to

How does phytohormone abscisic acid regulates plant flowering time?

Optimum of flowering time is most important for modern agricultural production system, especially for crops yield and seeds quality. Furthermore, during the lifecycle of a plant, one of the most attractive biological processes in plant research field

Processes mediating contaminant removal in Fe0/H2O systems: Coping with a highly dynamic system

The use of adsorption processes for water treatment purposes is a very old stuff. According to Egyptian and Sanskrit inscriptions, water was treated using filtration as early as 200 B.C. Its working principle is quite simple: its

Whole-cell computational models can predict how genes influence behavior

Since the early 1900’s, scientists have known that cells are composed of multiple components, including small molecules, DNA, RNA, and protein. Over the past fifty years, scientists have systematically measured these individual components and their interactions. Despite

Properties of magnetic nanocomposites for biomedical applications

Polymer nanocomposites have been receiving a lot of attention in the field of biomedical engineering. These composite materials, which consist of a polymer as the matrix and nanoparticles (nano-sized particles) as fillers, offer the opportunity for the

It is time to stop screening all women with mammography based on age alone

The early detection of breast cancer by mammography has been promoted in the Western world for decades, usually for all women 40-70+. Mammography involves an x-ray of the breasts while under compression. While mammography screening was once

Genes are read backwards to restructure our DNA

In English, we read in one direction – from left to right across the page. We need to read words in a certain order, so that the information makes sense to us. In the cells of our

Stem cell therapy for Parkinson’s disease

Parkinson’s disease is one of the most common neurodegenerative diseases of the central nervous system. Its main symptoms are motor disturbances such as tremors, rigidity and slowing of movements; although patients may also suffer from sleep disorders,

Albuminuria and cognitive decline

People with type 2 diabetes (T2DM) have a 50-100% increased risk of developing cognitive decline and dementia as compared to people without T2DM. The reasons for this decline are not yet clearly defined but are likely to