Daily Archives: March 18, 2016

A transcriptomic approach for cardiac (heart) safety assessment

New drug discovery relies on several phases of safety assessment. One such prominent in vitro safety assessment assay is the “hERG potassium channel assay” for cardiac safety. If a compound blocks the hERG potassium channel in a

Cushing’s Disease – why is the diagnosis so difficult?

Cushing’s disease, named after the neurosurgeon Harvey Cushing, and caused by an adrenocorticotroph hormone (ACTH)-secreting benign tumor of the pituitary, is a rare illness. The pituitary is a gland at the base of the brain that secretes

Tuberculosis in ancient bones can also be identified by a protein of the pathogen

As we all know, DNA is the matrix for the proteins and the proteins are the molecules which are involved in every step of the metabolism of all living organisms inside and outside of cells. Without proteins

From Biomass to Medicines: a cellulose derived product as building block in the synthesis of bioactive compounds

The bio-refinery concept is based on replacing fossil fuel with biomass, having the advantage to use renewable natural raw materials. This topic is currently of interest in academic studies, industrial applications and political strategies, both for the

UNC Medical Center reduces time patients wait for their chemotherapy

Lean and Six Sigma principles are used in manufacturing and more recently, healthcare, to eliminate waste, defects, and variability in processes. These philosophies are used to develop solutions to workflow challenges in an effort to improve process

Consuming a probiotic once a day could improve cognitive skills

Probiotics, which are friendly and beneficial bacteria to our bodies, could improve cognitive skills, i.e the ability to learn, memorise, process information or react to events, as demonstrated by researchers at the APC Microbiome Institute, University College

Is there a place for Tooth Mousse in the prevention and treatment of early tooth decay?

Despite significant improvements in oral health over the past forty years, tooth decay remains one of the most common health problems worldwide. The level of tooth decay found in low income and socially-disadvantaged areas remains a public