Daily Archives: May 4, 2018
How the mitochondrial F1FO-ATPase can be chemically switched on/off and serve as drug target
The mitochondrial F1FO-ATPase is well known to play the main role in synthesizing most of ATP, thus providing energy to living cells under aerobic conditions. However the enzyme complex can also work in reverse and split ATP
Early sepsis does not stimulate reactive oxygen species production and does not reduce cardiac function despite an increased inflammation status
Sepsis is due to bacterial infection. If it is sustained for several days, it can trigger severe abnormalities of cardiac function which leads to death in 50% of cases. This probably occurs through activation of toll-like receptors
