Author Archives: karen
A study to establishing the structural integrity of core−shell nanoparticles
Lanthanide – doped core – shell nanoparticles, such as NaYF4:Yb/Er@NaYF4, have attracted increasing attention for applications in photonics, photovoltaics, and biological imaging and therapeutics. When compared to conventional nanoparticles that suffer from extensive and uncontrollable dopant −
Reducing blood loss in brain surgery with extracranial early devascularization techniques
The anatomical region located under the frontal lobes of the brain, just above the eyes and the nose is called “anterior skull base”. The most common tumors involving this region arise from the soft tissue layers that
Fluorescent micro-RNA for cancer diagnostics
Biomarkers are indicators of biological states or conditions and can therefore provide important information about diseases such as cancer. In clinical diagnostics biomarkers are most often proteins or nucleic acids such as DNA or RNA. Biomarkers that
Adding phospholipid to drug formulation: a promising approach to improve drug absorption
For a patient to benefit from the therapeutic effects of any medicine, the prerequisite is that the drug is adequately absorbed after drug intake. Unfortunately, at least 40% of the marketed drugs and up to 90% of
The importance of parents in children’s reading skills
Home literacy environment explains between 12 and 18.5 % of the variance of children’s language skills. Although most authors agree that children whose parents encourage them to read tend to develop better and earlier reading skills, some authors
Oligodendrocyte Tau’s failed quest for microtubules results in myelin decrease and falling
Oligodendrocytes make a good-sized myelin that surrounds axons and allows humans to walk and see. In contrast, when axons do not get enough myelin, axonal function is incapacitated, with resulting deficits in cognition, behavior, and in the
A better understanding of cell division by combining mathematical modeling and experimentation
The cell division cycle is the process by which a growing cell replicates its genome and partitions the two copies of each chromosome to two daughter cells at division. It is of utmost importance to the perpetuation
Sensitivity to explosion of chemicals estimated using only a hand held calculator
The ability to predict the explosivity of energetic materials on the basis of their molecular structure would be of utmost interest for the design of explosives and propellants, to develop safe handling practices in the field and
Cold denaturation
Most proteins can be thought like beady chains which form compact well-ordered coils whose surface protects the greasy-like interior from the contact with water molecules. We are studying what are the forces which keep the coil compact.
Glutathione: a molecular whistleblower for Alzheimer’s disease
Alzheimer’s disease: Neurons in select pockets of the brain begin to die off, slowly and incrementally erasing an individual’s memory and eroding their individuality. It is a devastating disease, one that affects more than 36 million individuals
New drugs for cancer treatment
Cancer is a major cause of death and more than 1 million people in the United States are diagnosed with cancer each year. Finding more effective methods to treat cancer remains a challenge, and researchers are working
The CORAL software as spyglass to detect “coral reefs” in ocean of nanotechnologies
There are many messages about nanomaterials. There are the both bad and good facts. It is clear these substances are fastly penetrate into many fields of everyday life, such as food, cosmetics, pharmaceutics, electronics, etc. Therefore one
Some need to reduce blood pressure medication in hot weather
Many people take medication for blood pressure control. But there have been many reports suggesting (i) that dosage should be reduced in hot weather and (ii) a need for long-term individual studies. This paper presents a case
Metallic iron for environmental remediation: ending a myth
Iron corrosion is widely known as a destructive process. However, several useful applications of this process are known. Three examples are: consumption of humidity in food packaging, H2S removal from biogas and water treatment. Water treatment by
Cell division drives collective motion in cell monolayers
Cell division is essential to morphogenesis, tissue spreading, and tumor invasion. In particular, the hallmark of tumor invasion is the ability of cancerous cells to divide in extreme numbers. Our findings on the effect of cell division
Obesity causes lung dysfunction and breathing troubles by increased cysteinyl leukotrienes pathway
Increased body weight is a chronic health problem which has emanated from the globalized food market and dietary habit. This has led to the different types of ailments which occur in obese individual simultaneously and referred to
A functional defect of unconventional suppressor T-lymphocytes might lead to disease progression in lupus autoimmune patients
A healthy immune system discriminates between pathogenic invaders that have to be eliminated, and the body’s own tissues that have to be protected. Central to this role are immune cells called lymphocytes. B-lymphocytes are particularly important, because
Resveratrol is a potential remedy for the treatment of pancreatic fibrosis
The pancreas serves as both endocrine and exocrine glands in a human body in order to help food digestion and blood glucose regulation. In fact, more than 90% of the pancreatic mass comprises the exocrine cells which
Depression and dementia among American Indian and Alaska native elders
In the United States when talking about health care we tend to refer to national or state programs as uniform programs that are accessed by all U.S. citizens. . But there are groups that have a separate,
A potentially lethal condition that may occur in psychiatric patients
Antipsychotic drugs are commonly prescribed in patients with various psychiatric illnesses (e.g. psychosis, schizophrenia, aggressive behavior, etc.). A neurological emergency may arise characterized by muscle rigidity and damage, increased body temperature and cardio-respiratory system instability in patients
