Category Archives: Research
MYD88 mutation is associated with an unfavorable outcome of Primary Diffuse Large B-cell Lymphoma
Malignant lymphoma is a cancer of lymphocytes. This is actually a disease group consisting of multiple subtypes, among which diffuse large B-cell lymphoma (DLBCL) is characterized by diffuse proliferation of large B lymphoid cells. Primary DLBCL of
Implantable heart pumps improve functional independence in patients with advanced heart failure
The syndrome of advanced heart failure (AHF) occurs when the muscle of the heart loses its ability to effectively pump blood to the body. This results in poor delivery of oxygen and other nutrients to many organs,
Fungal-derived oligoglucosides protect Candida albicans from the immune system attack
Platelets play a crucial role in hemostasis, thrombosis, and pathogen clearance. Many pathogenic fungi can interact with platelets in circulating blood. This interaction between the fungus and the host occurs at the level of the fungal cell
How hard can a cell push?
Growth is a fundamental phenomenon in biological systems. It happens daily around us, such as growth of grasses and babies. Microscopically, the growth occurs at the single cell level. The volume of cells is approximately doubled from
Thymus and surgeon: an attractive and challenging gland
The thymus is a small gland sited in the anterior-superior mediastinum, approximately in the midline. It has an h-shape presenting two upper and two lower horns. It lies on the anterior surface of the pericardium starting from
Heat treatment of curdlan enhances enzymatic production of bioactive β-(1,3)-glucan oligosaccharides
Curdlan is a water insoluble linear β-(1,3)-glucan, which is industrially produced from bacterium. This polysaccharide displays irreversible gelation by heating, which has been applied in the food industry as stabilizers and food textures. However, those properties are
A new perspective on guided bone regeneration in foot surgery with heterologous materials
Guided bone regeneration (GBR), developed in 1976 by Melcher, is a surgical procedure used to increase the amount of bone volume. It uses barrier membranes with or without particulate bone grafts or/and bone substitutes. The basic principle
Big tasks for small flies: signaling cascades may help insects to detect faint odor traces
Have you ever wondered how a tiny vinegar fly manages to find its way to a ripened fruit in your kitchen? As many other insects flies possess a very keen sense of smell, which allows them to
Money is not enough for our health, but greater knowledge on how to spend it
It is well known that a low socioeconomic status is a major risk factor for health. Actually, deprived people do experience higher death rates and that is partly because of poor health behaviours (smoking, low exercise, poor
Reducing the failure rate of hip resurfacing in dysplasia patients
Arthritis secondary to developmental hip dysplasia often mandates implant surgery at a relatively young age. Hip resurfacing arthroplasty (HRA), compared with standard stemmed total hip arthroplasty (THA), affords a more active lifestyle including extreme-motion activities but stimulates
Barriers to implementing person-centered recovery planning in the public mental health system
Person-centered care is one of the six aims of healthcare quality established by the Institute of Medicine (2001). Person-centered recovery planning (PCRP) is a relatively new initiative in mental health care that refers to a process by
Comparing conservation metrics in a case study of lemurs
Deciding to which areas or species conservation actions should be allocated is, unfortunately, a very difficult process. On the one hand, time, money and resources are limited. On the other hand, it is unclear which points of
Who are easily to develop flood-related bacillary dysentery?
Climate change has already brought and will continue to bring about challenges to public health on a global scale. In particular, it is estimated that floods have affected 2.8 billion people and killed 200,000 during the past
Penetration ability of caffeine and propylene glycol in the skin
The stratum corneum (SC) is the uppermost layer of the skin, which provides an efficient barrier function. This barrier is always an obstacle for cosmetic formulations or medical ointments applied to the skin. The permeation through the
The ADHD diagnose – a way of masking problems in society?
Difficulties with attention and hyperactivity among children have gained increasing concern during the past decades. Journalists, policy makers, researchers, teachers, healthcare professional, social workers, parents and others discuss how children with such difficulties should be understood and
Genital melanoma or genital nevus? Molecular answers to a sensitive question
Melanomas arising in the genital region of women are rare although they are the second most common type of cancer in this area. They occur more frequently in women after menopause and tend to be aggressive because
A new chance for rapamycin
Rapamycin is a bacterially-produced drug first discovered in the soil of Easter Island, and currently used as an immunosuppressant for organ transplantation and the treatment of certain types of cancer. Rapamycin has received popular attention following the
Understanding analogies depend on the integrity of the anterior human prefrontal cortex
In our representation of the world, how do we link distinct domains of knowledge? We employ analogical reasoning. By using analogies, we can identify similarities between distinct situations, allowing us to solve new problems, transfer solutions from
Recycling polymers in the presence of carbon dioxide
Polymers are large molecules which are formed from the joining of smaller molecules (monomers) in a process called polymerisation. They are present in many of the commercial products which we use on a daily basis, from laptops
