What pH at the sites of calcification of an octocoral tells us

What pH at the sites of calcification of an octocoral tells us

Corals are marine organisms which elaborate calcium carbonate skeletons, a process known as biomineralization or calcification. More »

Zinc promotes myoblast differentiation activating Zip7 transporter and Akt signalling pathway

Zinc promotes myoblast differentiation activating Zip7 transporter and Akt signalling pathway

Skeletal muscle is a heterogeneous, dynamic and plastic tissue, which comprises 40% of adult human body mass. More »

Any cell organelle can be the starting point for toxicant and pathogen-induced cell death

Any cell organelle can be the starting point for toxicant and pathogen-induced cell death

Toxicants and pathogens often induce death of their target and host cells. In order to investigate the different ways they can achieve this More »

Metal-organic framework with dangling sulfonate groups for enhanced proton conductivity

Metal-organic framework with dangling sulfonate groups for enhanced proton conductivity

Metal-organic frameworks (MOFs) provide a versatile platform for tuning the chemical functionality of pore surfaces and thus have attracted an increasing amount of attention for applications in gas storage More »

 

A novel measure for predicting OSA whilst awake

AoS.A Novel Measure for predicting OSA whilst awake

Obstructive sleep apnea (OSA) is a common sleep disorder, and its prevalence increases significantly with age. Despite being massively under-diagnosed, the latest estimation of OSA prevalence is >1 billion globally. OSA diagnosis is based on an overnight

Experiences of other identities and Dissociative Identity Disorders in the continuum of Non-Ordinary Mental Expressions

AoS.Experiences of other identities and Dissociative Identity Disorders

Dissociative Identity Disorders (DIDs) – including experiences of other identities, multiple personality and possession – are an intriguing topic entailing deep historical, cultural and epistemological implications that run through the entire history of the human kind. Indeed,

Nanomaterials as promising alternative in the infection treatment

AoS. Nanomaterials as Promising Alternative in the Infection Treatment.

Nanotechnology offers groundbreaking solutions for the management of infections in the current era when the vast majority of antibiotics has become inefficient. Overcoming antimicrobial resistance and biofilm formation constitute a major challenge.  In this review, we focus

Short sleep duration is associated with symptoms of depression

AoS.Short Sleep Duration is Associated with Symptoms of Depression

The average person spends about a third of his life sleeping, but for the busy and the ambitious that is a lot of time.  Many of us would rather spend that time working on important projects or

Specific and non-specific biomarkers in neuroendocrine gastroenteropancreatic tumors

Neuroendocrine tumors (NETs) are a heterogeneous group of rare malignancies that can arise in almost all organs, although gastroenteropancreatic site (GEP) is the most common. Symptoms are rarely specific, and clinical manifestations may be evident only in

Capturing hydrogen transfer from modeling: a small step towards simulating chemical reactions by computers

AoS. Capturing Hydrogen Transfer from Modeling

All the matter of the world around us are made of atoms that are joined to form molecules. Chemists can create new molecules by changing connectivity of atoms in molecules through chemical reactions. Researchers can control reaction

The past shapes the future: How socio-environmental conditions affect growth and sexual dimorphism

AoS. The past shapes your the future

Sexual size dimorphism (SSD) is the difference in body size between males and females of the same species, which is common among mammals with males typically being larger. Sexual selection is thought to be the main cause

What drives the syneresis of lacto-fermented sodium caseinate?

Fermented dairy products have a great nutritional value and health beneficial effect on host gut micro-biome, due to their probiotics bacteria. Syneresis is considered as a major defect in these acid-induced gels products, which is a major

Intense light boosts the circadian function of cardiac vessels which protects from heart attacks

Humans are daily exposed to intense light in the form of sunlight which is crucial for the circadian rhythms in our bodies to properly function. This is important as circadian rhythms regulate all physiological processes in the

Matching between adult neurons: feel abandoned? Just call on me

AoS.Matching between adult neurons

Plasticity in the central nervous system allows the adaptation of neural circuits to new circumstances, such as the recovery after brain injury. The mechanisms of neural plasticity include, among others, the formation of new synapses. An example

Ultrasound generate electricity inside the body

AoS. Ultrasound generate electricity inside the body.

Implantable medical devices (IMDs) are highly beneficial to patient health. Concerning rapidly evolving technologies for IMDs, sustainable and reliable powering methods for IMDs is truly essential. They are generally relying on primary batteries, which are subject to

A molecular passport authorizes intracellular travel for a potential cancer therapy antibody

AoS. A Molecular Passport Authorizes Intracellular Travel for a Potential Cancer.

Whether from external environmental factors or spontaneous intracellular processes, the DNA in our cells is under constant bombardment by DNA damage. Because unrepaired DNA damage can cause cell death, our cells have evolved vital mechanisms to repair

What treatment is really medically and economically desirable for chronic hepatitis C patients with treatment failure after 8-week glecaprevir/pibrentasvir in Japan?

Currently, direct-acting agent (DAA) therapies have high efficacy and safety and are the main strategy to eliminate hepatitis C virus (HCV) worldwide. Some DAA therapies are also effective for HCV-infected patients who have experienced prior DAA failure.

Botryococcus braunii – A potential source of high value chemicals

AoSBotryococcus braunii - A potential source of high value chemicals.

High value biochemicals, including lipid, protein, polysaccharide, and carotenoid, etc. are gaining significant attention in energy development and waste resource utilization. Among a variety of high-value feedstocks, microalgae are particularly promising because of their high value biochemicals

Chronic unpredictable environmental stress is harmful to humans

Stress refers to the mental and emotional change of state from normal homeostasis. In another words we can say that stress happens when we are worried for something and feeling uncomfortable. Chronic unpredictable environmental stress (CUES) refers

Cuddling of babies born extremely preterm before admission to the Neonatal Intensive Care Unit

Delivery of a baby before 37 weeks’ gestation is known as premature birth. Some babies may be born more than 12 weeks early – at 27 weeks’ gestation or even less. This is commonly termed ‘extremely preterm’.

Function matters: visual stimulation protects the retina against ischemia

AoS. Function matters: visual stimulation protects the retina against ischemia.

Retinal ischemia is a condition involved in several prevalent retinal degenerative diseases such as glaucoma and diabetic retinopathy, which cause visual impairment and blindness. Current research focuses on the development of neuroprotective strategies against ischemic retinopathies, but

Why constrain human taxonomic diversity?

Although the discovery of ancient humans remains was first reported in 1833, the Neanderthal bones from Feldhofer Grotto were the first to receive a species name: Homo neanderthalensis (King 1865). In 1894, Dubois boldly referred “ape-man” specimens

Allosteric degraders of EGFR leading to cancer cell detachment-promoted death

AoS. Allosteric Degraders of EGFR Leading to Cancer.

Epidermal growth factor receptor (EGFR) allosteric tyrosine kinase inhibitors (TKIs) have emerged as a therapeutic option for overcoming drug resistance in cancer. We have developed furfuryl derivatives of 4-allyl-5-[2-(4-alkoxyphenyl)-quinolin-4-yl]-4H-1,2,4-triazole-3-thiol and have shown that these compounds bind to

The minimally invasive and percutaneous ways: A tale of two approaches for heart valve implantation

AoS.The minimally invasive and percutaneous ways.

Over the decades, advances in medicine have led to large increases in life-expectancy, a fact most are grateful for. However, accompanying this boost in longevity we also find a rise in what are known as “aging-related diseases”,