Tag Archives: disease
The protective role of estrogens in prostate cancer and its relationship with the SCF/c-KIT system
Prostate Cancer (PCa) is the most common oncological disorder in men worldwide, mainly affecting individuals over the age of 50. Therefore, the population aging and the improved expectancy of life have been contributing to the increased incidence
Muscle stem cells fail to become activated in Pompe disease and do not repair the accumulating muscle damage
Skeletal muscle is the largest organ of the body and is responsible not only for movement , breathing and posture, but is also important in regulating body temperature. It is not surprising that defects in muscle function
Can inhaled formoterol be used to prevent hypoglycemia?
Patients with type 1 diabetes need insulin treatment for their survival. However insulin can cause low blood sugar (or hypoglycemia); a major limiting factor for good diabetes control. Hypoglycemia occurs when there is an excess of insulin
Lipids are major players in Alzheimer’s disease
Alzheimer’s disease is the most common neurodegenerative disorder affecting over 36 million people worldwide. Alzheimer’s patients suffer from dementia and memory loss and go through a progressive, irreversible and eventually fatal loss of cognitive functions. When Alois
The potential of chitosan in prevention and treatment of age-related diseases
According to the recent report of The Department of Economic and Social Affairs of the United Nations Secretariat the number of elderly (aged 60 years or over) is expected to increase from 841 million people in 2013
Active-state of AT1 receptor attenuates inverse agonism of ARBs through changes in specific ligand-receptor interactions
G protein – coupled receptors (GPCRs) constitute one of the largest gene superfamilies in the human genome. The angiotensin II ( Ang II ) type 1 receptor ( AT1R ) belongs to G – protein coupled receptor
Fatty liver disease: a condition caused by modern day lifestyle
Non-alcoholic fatty liver disease (NAFLD) refers to the build-up of fat (steatosis) in the liver that occurs in the setting of obesity and/or diabetes. Specifically, other causes such as alcohol excess or drugs or genetic conditions need
A monkey’s life is full of stress: pressures from a disease and the lack of good food and their effects on abundance
Despite strong links between patterns that individuals deal with others and their success at breeding that ultimately affect the size of animal populations, the particular social and ecological factors that lead to endangerment are not well understood.
Thyroid eye disease: early catch, better fix
Thyroid eye disease (TED) is an uncommon condition that affects some people with an overactive thyroid (a condition called Graves’ disease, of whom about a quarter will develop TED). The disease causes swelling of the tissues behind
Spinal tumors in children: a rare disease
Tumors of the Central Nervous System (CNS) are one of the first causes of morbidity and mortality in children in developed countries. Among them, spinal tumors are estimated to account for less than 10% of the cases,
Proposed novel therapy for a sexually transmitted disease
Neisseria gonorrhoeae (NG) is one of the seven pathogens that cause sexually transmitted disease, also popularly known as venereal disease. The NG infections are contagious. Their prevalence is higher among women than in men, high among sexually
Morgellons disease: the search for a perpetrator
Morgellons disease is a poorly understood skin condition associated with Lyme disease. Patients suffering from the disease often have spontaneously-appearing, slowly-healing skin ulcers and may have crawling or stinging sensations in their skin. They may have one
Bones of contention: Bone mineral recovery in celiac disease
Low bone density is common in newly diagnosed patients with celiac disease (CD). Untreated CD leads to bone fractures and osteoporosis in young and older patients. The gluten-free diet (GFD) is the primary treatment for CD. Bone
Total ankle replacements in diabetics
Diabetes is a growing public health concern with 380 million people worldwide projected to have the disease by 2025. With over 1% of the world’s population having ankle arthritis, many diabetic patients will require operative treatment. Modern
High prevalence of undertreated cardiovascular disease in patients diagnosed with cancer
Heart disease and cancer are the most common causes of death in the United States. They often have the same risk factors (for example, smoking, advancing age, obesity). Heart disease can worsen outcomes after cancer therapy and
Resting state fMRI analysis using sparse dictionary learning in SPM framework
Brain always be active even people are in rest. In the resting period, it has been observed that particular groups of brain region are always co-activated. These regions are functionally connected each other and each group is
A possible new treatment for Alzheimer’s disease and stroke using nanoparticles
Alzheimer’s disease (AD) and stroke are two neurological disorders that share the common feature of neuronal death. The peptide under investigation here is IRL-1620, which has been shown in previous studies to reverse neuronal death as well
A formula for better asthma, cold and heart medications
Imagine that you had found a way to drop the dose of your asthma medication ten-fold, increase its duration of activity from a couple of hours to all day, and still get the same relief as before.
What role do medications play in changes in sexual activity after a heart problem?
Heart disease affects millions of people worldwide. While advances in medical treatment have allowed many with heart disease to live longer, healthier lives, changes in quality of life often occur. This is particularly true for sexual activity,
Metformin is a potential remedy for the treatment of Gaucher disease
Glycosphingolipids (GSLs) are amphipathic compounds consisting of oligosaccharides and hydrophobic chain of ceramide. They are ubiquitously distributed in the outer leaflet of the plasma membrane and believed to be involved in a large number of cellular processes,
