Tag Archives: genes

The ‘fundamental questions of obesity’: Asked and answered

Fundamental Questions of Obesity. AoS

Scientific progress requires the ability to discover which questions are essential and which are trivial. Yet until recently, there were three fundamental questions that were ignored in nutrition & obesity research: What is the defining characteristic of

Gene sequencing validation for select commercial turkey genes

Gene expression analysis via polymerase chain reaction (PCR) is a common tool used to determine, using molecular techniques, the physiological basis underlying  experiments with animal tissues.   Some genes are “turned on” and others silenced in response to

Plants versus pathogens: detection and deception

Novel research has unveiled more about the deception tactics used by plants in their continuous battle against attacks from disease-causing pathogens. These findings could help in breeding better crops to reduce losses and produce more food. In

β-Carotene requirement for anti-aging depends on genetic background

Cellular telomere, a region of repetitive nucleotide sequences of TTAGGG, resides on both ends of chromosomes and its length is shortened by reflecting the replication number of chromosomal DNA, accordingly, telomere length is the most reliable indicator

Aberrantly methylated DNA regions in IgA Nephropathy patients affect the disease

The genome can influence the onset and the development of the diseases in several manner, and in the last years several studies have revealed the new role of the DNA methylation in this framework. The DNA methylation

The genetic secrets of Uveal Melanoma

Uveal melanoma (UM) is the most common primary cancer occurring in the eyes of adults, with 1/100,000 new cases per year in the Western world. Most patients are between 60 and 65 years old. Although it is a

TGFbeta signalopathies as a paradigm for translation medicine

Marfan syndrome (MFS) is a disorder that affects different organ systems, such as the heart, aorta, eyes and the skeleton. Typically MFS patients present with tall stature, hands with long fingers, chest deformity. One of its most

Genetics and dietary stress explain low calcium absorption

It is well understood that osteoporosis is influenced by a variety of environmental factors such as age, nutrition, and race. Calcium absorption is one of these important factors and low levels of calcium absorption have been associated

A factor that regulates the expression of HIV genes

Proteins are the machinery of life. Nearly everything in a cell is manufactured by, regulated by or composed of proteins, which are encoded in genes. When a cell needs a particular protein, the DNA encoding the protein

High-Resolution chromosome ideogram representation of recognized genes for autism spectrum disorders

Classical autism which is termed as an autistic disorder belongs to the autism spectrum disorders (ASD). Autism was first coined in 1943 by Dr. Kanner. Individuals with ASD may be diagnosed as early as three years of

Birth weight is not solely determined by genetic code

It is believed that genetic information carried by our DNA determines our metabolism and how we look. This is especially true for identical twins. The incidence of identical twins is around one in every 200 deliveries. Although

Rare and uncommon cancers

A rare cancer is one that occurs less than 6 times in 100,000 people and an uncommon cancer is found between 6 and 12 times in each 100,000 people. The problem with being rare is that there

Genes are read backwards to restructure our DNA

In English, we read in one direction – from left to right across the page. We need to read words in a certain order, so that the information makes sense to us. In the cells of our

Punching above their weight: how the smallest RNAs offer great promise for cancer biology

In recent decades, scientists have witnessed transformative developments in the field of RNA biology. RNA molecules are similar in composition to their more famous DNA counterparts (they are both nucleic acids), but are present in a variety