Tag Archives: therapy
A new role for vitamin D3
Mutations in the genome of body cells (somatic cells) can lead to excess activation of signaling pathways and thus to unlimited cellular proliferation and cancer formation. One such cancer-inducing pathway is the Hedgehog (Hh) signaling cascade, which
Identification of a novel factor implicated in the resistance of cancer to the therapy
Therapeutic treatment of cancer involves radiotherapy and/or chemotherapy so to generate a large amount of lesions in the DNA. Because cancer cells have reduced capacity to repair DNA lesions and are unable to slow down proliferation, this
A small structure hidden in the brain that might play a big role in diseases like depression and autism
The choroid plexus is a hidden and often neglected, but important, structure in the brain. The choroid plexus hangs inside the brain ventricles which are filled with cerebrospinal fluid (CSF) (Fig. 1). Importantly, the choroid plexus is
Effect of resveratrol on chemotherapy of a fatal childhood cancer
The natural polyphenolic compound resveratrol, found in red wine, dark chocolate, and peanuts, may confer health benefits in humans. It is a powerful antioxidant that has been suggested to alleviate age-related pathologies, such as type II diabetes,
Nanocarrier-based antioxidant therapy: promise or delusion?
It has been well established that the damage produced by Reactive Oxygen Species (ROS), which are highly reactive molecules with an unpaired electron, plays an important role in a large number of human diseases. Because of this
How to optimize the effectiveness of anticancer therapy
Hepatocellular carcinoma (HCC) is the most common type of liver cancer. HCC is a public health problem worldwide because of its high incidence and its poor prognosis with high cancer-related mortality. In the majority of cases, patients
Nanoformulations for cancer therapy
Cancer is a major disease responsible for death in human beings. A lot of research has been performed to develop improved diagnostic tools as well as drugs to treat cancer. Effectiveness of therapeutics in cancerous malignancy is
New drugs for cancer treatment
Cancer is a major cause of death and more than 1 million people in the United States are diagnosed with cancer each year. Finding more effective methods to treat cancer remains a challenge, and researchers are working
Blood-based biomarkers for multiple sclerosis
Multiple sclerosis (MS) is an immune-mediated, inflammatory demyelinating and neurodegenerative disease of the central nervous system (CNS). MS is classified in: relapsing–remitting (RRMS), characterized by acute attacks followed by partial or complete recovery periods; primary progressive (PPMS),
Save your pancreas from diabetes! Your beta cell reserve is critical for prevention and treatment of diabetes.
To date the number of people with diabetes is estimated to be 387 million over the world. This number is continuing to increase and predicted to be 592 million in 2035. Despite the recent advance in the
Gene therapy not just counseling for your denim obsession
Imagine a world where one size does not fit all, wait that’s the world we live in now. So why is the treatment you get under the “one size fits all” umbrella, we are all different, right?
Combining different antibody flavors to improve cancer therapy
Our immune system is specialized at identifying ‘foreign intruders’ (pathogens) or virus-infected cells inside the human body. This can be achieved by antibodies (immunoglobulins) that circulate in our body and are able to bind targets with high
The risk of death from high-risk prostate cancer in men undergoing EBRT and brachytherapy
According to the National Comprehensive Cancer Network (NCCN) guidelines, treatment with long-course (28–36 months) androgen deprivation therapy (ADT), in addition to brachytherapy (where radioactive seeds are implanted inside the prostate to kill cancer cells) and external beam radiation
