Monthly Archives: November 2015

Electrocardiogram screening in athletes:

A Good Return on Investment? In Austin, Texas, a bill requiring an electrocardiogram (ECG/EKG) as part of high-school athletes almost passed. An ECG is a non-evasive electrical tracing of the heart, which can reveal underlying heart conditions

AMPK: Common mechanism of action linking HIV-1 latency and Hutchinson-Gilford progeria syndrome

Although any connection between HIV-1, the virus that causes AIDS, and Hutchinson-Gilford progeria syndrome, a rare genetic disorder that exhibits symptoms of accelerated aging in children, would appear unlikely, splicing of the latent ( i. e. dormant)

Natural history of multiple system atrophy in USA

Multiple system atrophy (MSA) is a rare, fatal brain disorder exhibiting a combination of parkinsonism and/or cerebellar gait unsteadiness and autonomic failure. Autonomic failure, manifest as orthostatic hypotension, severe constipation and urinary incontinence or retention, as well

Phospholipases have a second job, regulating their G proteins

Can we make a weak heart healthy? Can we prevent decline in memory and cognitive ability? The answer may depend on a class of enzymes, phospholipase C (PLC), and their under-investigated ability to directly regulate their specific

Chip-based microacoustic aerosols generators

Aerosols consist of a large quantity of either liquid droplets (fog, mist) or solid particles (dust, smoke) dispersed in a surrounding gas (e.g. air). They occur naturally and they can as well be generated artificially, e.g. by

Ergothioneine prevent UVA – induced skin damage through its potent antioxidant property

It is well – known that continuous exposure to ultraviolet ( UV ) radiation from sunlight can cause mild to severe skin damage, characterized by wrinkles, inflammation, photoaging, pigmentation, photo – carcinogenesis, photo – dermatoses etc. Most

Nanocarrier-based antioxidant therapy: promise or delusion?

It has been well established that the damage produced by Reactive Oxygen Species (ROS), which are highly reactive molecules with an unpaired electron, plays an important role in a large number of human diseases. Because of this

A disease of younger women

Cramp or pain during menstruation is very common, but telling a young woman that this is ‘normal’ without full assessment can be wrong as this can lead to many years of unnecessary suffering. There are many conditions

Antimicrobial resistance – what’s needed but how to get the resources to the innovators?

Antibiotic resistance is at a crisis point, nay a “tipping point”. There are several major programs which offer what sound like large sums of money to make new antibiotics, but to get these monies takes a lot

What is really driving our need for food, besides the pleasure of taste?

We all know that this need is related, in some way, with life sustainability, but just how, exactly? The task of converting food into energy –and back again into organic compounds– is carried out by our metabolism,

Hybridisation masks speciation in marine iguanas

The Galápagos archipelago is an isolated group of islands which serve as a natural laboratory for the study of evolution. The islands are home to the marine iguana – a highly specialised sea-going lizard which is found

The role of the Amazonian forest in removing atmospheric mercury

Mercury (Hg) is a naturally-occurring chemical element found in rock in the earth’s crust, including in deposits of coal and oil. Nevertheless, it is considered by the Word Health Organization as one of the top ten chemicals of

Effects of dietary peppermint on fry Caspian white fish

Traditional medicines usually involve the use of plant extracts. Among these plants, mint species have been exploited by man since more than two thousand years. Mentha piperita (also known as peppermint) is one of the world’s oldest

Palpable melanoma groin lymph node metastases

Melanoma is the most lethal type of skin cancer. In 2012 232,130 persons were diagnosed worldwide, and 55,488 estimated deaths occurred due to melanoma. Patients who present with a palpable lymph node metastasis in the groin area

High blood pressure is controlled more effectively by two drugs in one pill

Hypertension, or high blood pressure (BP), is a major global public health problem, both because of how common it is and its correlation with cardiovascular disease. It has been identified as one of the major risk factors

Are mindfulness apps good enough?

My mind tricks me. I either ruminate about the things I always wanted to do but never did or worry about something that’s yet to happen. I’m lost in meaningless thoughts, empowering them, ignoring the present moment.

New and future strategies for asthma control in children

Asthma continues to be a predominant health concern in children despite advances in medical care. Children are being diagnosed with asthma at earlier ages, and the adverse effects of early-onset, poorly controlled asthma can last throughout childhood

Can we stop dentist drilling too much on our caries tooth?

Dental caries is one of the most prevalent diseases worldwide. It is a result of hard tissue demineralization largely caused by acid produced by bacteria on the tooth surfaces as a by-product of metabolism of fermentable carbohydrate.

MicroRNAs and physical activity

Physical activity has a recognised role in the prevention of non-communicable diseases, cancer included. To maintain a satisfying health level, the World Health Organization (WHO) has assumed that everyone have to practice at least 150 minutes of

Measuring what cells feel using the nano-epsilon dot method

When we walk on the sand, a trampoline or a concrete pavement, we can feel the hardness, softness and springiness of the ground and respond by changing the way we move. The way we respond depends on