Monthly Archives: January 2016

Slug transcription factor activates its own expression during epithelial to mesenchymal transition

Cancer is a highly aggressive and challenging disease. In several instances, symptoms are not evident until the disease progresses to an advanced stage and hence, it is amongst the leading causes of human mortality. Despite considerable attempts

Birth weight is not solely determined by genetic code

It is believed that genetic information carried by our DNA determines our metabolism and how we look. This is especially true for identical twins. The incidence of identical twins is around one in every 200 deliveries. Although

Small-molecule RETRA is effective against a fatal childhood cancer

The bone tumor Ewing’s sarcoma is one of the most aggressive cancers in childhood and adolescence. Before the era of chemotherapy, more than 90% of Ewing’s sarcoma patients succumbed to their disease. With the introduction of intensive

Bone marrow transplantation resets the clock in patients with Chronic Lymphocytic Leukemia

Chronic Lymphocytic Leukemia (CLL) accounts for about one third of all of leukemias. In the United States 15,000 patients are diagnosed with and 4,500 patients die of CLL every year.  CLL is a diverse disease. Some patients

Comparison of biological and cultural evolution

Biological evolution is a population-level process guided by selection, and it leads to an increase of the adaptation of the population for the environmental circumstances in which the population lives. Culture can be defined as the wholeness of

Rare and uncommon cancers

A rare cancer is one that occurs less than 6 times in 100,000 people and an uncommon cancer is found between 6 and 12 times in each 100,000 people. The problem with being rare is that there

Controlling self-assembly processes on 2-D surface

Supramolecular self-assembly on two-dimensional (2-D) surface is a powerful approach to construct functionalized surfaces. In a self-assembly process, molecules assemble via noncovalent interactions such as van der Waals or hydrogen bonding interactions, and form periodic nano structures.

Efficient tuning of carbon surface: Defect-enriched CNT

To face energy and environmental issues, the importance towards development of novel catalytic materials with clean and highly efficient feature is self-evident, since the catalysis is the cornerstone for chemical industries. The development of low-cost sustainable catalysts

Single crystalline tantalum oxychloride microcubes

Tantalum oxides usually refer to a class of substances deriving from Ta2O5, and have advantages of high dielectric constant, big refractive index, low internal stress, as well as large bandgap and resistivity. These advantages endow them with

Observing the SAfETy of our schools

Last year, the Report Card for America’s Infrastructure gave schools a D. The reasons for this near failing grade centered on the lack of investment in either maintaining older buildings or building new schools to accommodate increasing

Genetically encoded voltage indicators for large scale cortical imaging come of age

Composed of billions of neurons, the brain is the most complex organ that dictates our daily lives. Naturally, understanding the brain is one of the final frontiers that would not only provide basic understanding but also sprout

Promote the health of dementia caregivers

The vast majority of the care for people with Alzheimer’s dementia is and will be carried out by informal caregivers as health care services across the world cut funding. This is a major concern in an aging

Milk fatty acids as possible biomarkers to diagnose hyperketonemia in early lactation

Aim of this study was to assess the potential of milk fatty acids (FA) as a diagnostic tool for hyperketonemia. Negative energy balance is a common phenomenon in the transition period in dairy cows. During this period,

Two essential cardiac disorders improvement in patients with hypertrophic cardiomyopathy

Sudden cardiac death and heart failure are the most serious complications of hypertrophic cardiomyopathy ( HCM ). To prevent these serious complications, 2 essential cardiac disorders in patients with HCM must be corrected. These are left ventricular (LV)

Stepping to recover from a fall is not helped by Deep Brain Stimulation in people with Parkinson’s disease

Poor balance is common in people with Parkinson’s Disease and can limit the activities people are able to engage in. If a fall occurs the injuries can be debilitating and impair quality of life. The ability to

Spousal assaulters in outpatient mental health care

Domestic violence is defined as: ‘a physical, mental or sexual violation of the personal integrity of the victim by a person from the victim’s family circle. This includes (ex)-partners, family members and family friends of the victim’

Virus containing mealybug DNA kills mealybug

One way of self-regulating protein synthesis by animals is suppression of the relevant messenger RNA (mRNA); molecules that translate into amino acids and act as building blocks for protein. The mechanism, called RNA interference (RNAi), works by

Silence the uncontrolled cancer cells’ growth by controlling cellular senescence

When toxic damage caused by environmental or internal stressors accumulates cells can either stop proliferation permanently ( cellular senescence ) or die. Cell death is a common goal of existing cancer therapies, yet cellular senescence is increasingly

Electroconvulsive therapy without seizures?

Electroconvulsive therapy (ECT), sometimes called “electroshock therapy” is considered the most effective short-term treatment available for major depression. The procedure involves passing electrical current through the brain with electrodes placed on the scalp and is done in

Are all babies born in the same way?

Are all babies born in the same way? Some come into this world in a natural way, some through Cesarean section, some with the help of episiotomy, “the unkindest cut of all”, performed with scissors, obliquely and