Yearly Archives: 2019

The synthetic cannabinoid XLR-11 and the impaired control of mitochondrial function by the endocannabinoid system as its underlying mechanism of nephrotoxicity

mitochondrial function by the endocannabinoid system

Synthetic cannabinoids (SCs) comprise a diverse group of new psychoactive substances (NPS) designed to activate at least one of the main cannabinoid receptors (i.e. CB1R, CB2R). Variations of SC have rapidly surfaced over the past few years,

How can writing help with mental health?

How can writing help with mental health

Posted by Sully Davis Over the years, many positive attributes have been connected to writing, whether it’s just keeping a diary or writing on interesting stuff. Of course, those who are mostly involved in college research papers and

How salt hate your bones: the nexus between high dietary salt intake and bone loss

High dietary salt intake induces bone loss by enhancing bone lethal Th17 cells and suppressing bone protecting Treg cells.

Osteoporosis weaken bones making them fragile and highly susceptible to fractures due to reduction in bone mass via depletion of bone minerals. This leads to higher incidences of fractures many folds responsible for enhanced morbidity and mortality.

Developing attention networks in children with different temperaments

Brain Networks of Attention

Attention Networks Brain imaging has provided a great window on how networks of neural areas develop from birth through adulthood. The infant comes to control the waking state during the early months of life. During waking periods

Cryptosporidium and Giardia detection: Microscopy to genetic signature based methods

Cryptosporidium and Giardia are the most commonly occurring enteric protozoan parasites. These pathogens can cause gastrointestinal diseases that may lead to nutritional imbalances and severe health problems. The severity of disease is most often seen among children

Fatal asthma, thunderstorms and grass pollen

Pathogenesis of thunderstorm asthma

More than a dozen epidemics of thunderstorm-related acute severe asthma have been reported in past 3 decades. The largest event occurred in Melbourne Australia (October 2016) affected more than 8,000 individuals and resulted in ten deaths. This

Observing marine plastic litter from space, a supporting model

Reflectance spectra of high-density polyethylene

There is growing global concern over the plastics pollution of our oceans and the many unanswered questions about its sources, sinks, pathways and impacts. Remote sensing (RS), the science of obtaining information about objects or areas from

Cardiac autonomic neuropathy: Risk factors, diagnosis and treatment

Cardiac autonomic neuropathy (CAN) is a serious complication of diabetes mellitus (DM) that is strongly associated with approximately five-fold increased risk of cardiovascular mortality. CAN manifests in a spectrum of things, ranging from resting tachycardia and fixed

Under pressure: a stem cell’s journey home

A Stem Cell’s Journey Home

Hyperbaric oxygen therapy (HBOT) involves breathing in pure oxygen at an air pressure three times higher than atmospheric pressure. This allows more oxygen to enter the lungs, dissolve into the circulation, and ultimately reach cells. The future

Leptomeningeal metastasis in lung cancer

Leptomeningeal metastasis is the spread of cancer cells to the membranes surrounding the brain and spinal cord as well as the cerebrospinal fluid (CSF). This occurs in 3-5% of patients with non-small cell lung cancer (NSCLC), the

Body composition and left ventricular hypertrophy in athletes: the role of body cell mass

Body composition and left ventricular hypertrophy in athletes

Cardiac adaptation to intense physical training is determined by many factors including age, lifestyle, body size, training load, ethnicity and sex. Females show a lower cardiac mass than males, the main causes are a lower blood volume

Single dose protection against lethal Ebola virus challenge

Electron micrograph showing formation of MVA-EBOV VLPs

Ebola virus disease (EVD) is a fast-progressing, highly lethal illness that poses significant threat to global public health when not contained. The current outbreak in the Democratic Republic of the Congo, as of February 26, 2019, has

2nd Annual Conference on Pediatric Nursing and Healthcare. Dubai, UAE. June 17-18, 2019

2nd Annual Conference on Pediatric Nursing and Healthcare

2nd Annual Conference on Pediatric Nursing and Healthcare scheduled during June 17-18, 2019 in Dubai, UAE which aims to keep you updated with the best and most advanced practices in the field of pediatrics, nursing and health.

Is too much “good” cholesterol a health risk?

There are thought to be good and bad types of cholesterol. High-density lipoprotein cholesterol (HDL-C) is thought to be a good type of cholesterol because it is believed to remove bad types of cholesterol from blood vessel

Phage therapy: a one-hundred-year-old alternative to modern, chemical antibiotics

Google Scholar searches on the query

Phage therapy is the use of bacterial viruses, known as bacteriophages, or phages, to control or eliminate problematic bacteria (Fig. 1). Targeted bacteria can range from biofouling agents to agricultural pests to human pathogens, etc. As has

Substrate phosphoswitching: a novel way to regulate enzymatic activity by phosphorylation of its substrate

Schematic diagrams for the GTPase cycle

Cells sense a vast variety of signals by receptors that are distributed on their surface. This perception transduces internal physiological responses using signal pathways, a cascade of protein interacting to bring a change in the cell behavior.

Aspen fungal endophyte communities are enriched after herbivory by leaf eating Chrysomelid beetles

Bipartite graph of the relationship between the SwAsp genets

Aspen trees grow abundantly and extensively across the forests of the northern hemisphere. They are early succession species that can quickly establish after fires or storms, and they also support a high biodiversity.  While the biodiversity associated

Apple cider vinegar can help clear bacteria and yeast infections; a natural cure

The effect of apple cider vinegar on white blood cell clearance of microbes.

Antibiotic resistance poses a major health issue worldwide. There has never been a greater need for new anti-microbials which are natural, active on multiple organisms and ideally beneficial to the patient. Bacteria such as E-Coli, Staphylococcus aureus

Evaluation of a dialectical behavior therapy training model in residential programs

Dialectical behavior therapy is a cognitive theory-based intervention that has previously demonstrated effectiveness in treating a range of behavioral disorders. However, DBT can be challenging to implement in community-based settings. Little guidance is available on models to

Optimal level of membrane cholesterol guarantees the proper functioning of Kv channels

depletion or enrichment of plasma membrane cholesterol

Cholesterol is the most abundant lipid of the mammalian plasma membrane. It is well known that cholesterol influences membrane biophysical properties and regulates the activity of multiple types of ion channels, including K+ channels. The reported mechanisms