Yearly Archives: 2020
Role of ultrasonography in the evaluation of traumatic injury to peripheral nerves
Traumatic injury of peripheral nerve accounts for about 3-5% of limb trauma, but if not diagnosed it can be associated with negative outcomes, especially in major trauma, with economic and social damage when working-age subjects are involved.
Forward and reverse mutations in stages of cancer development
Mutations in somatic genomes are known to be the basis of cancers, understanding of which is essential for cancer prevention, diagnosis and therapy. In our study, mutations changing the genomic DNA sequences of a cell from its
Production techniques for the development of sub-micron size polymeric drug delivery formulations evaluated
Polymeric drug delivery formulations containing active pharmaceutical ingredients (APIs) offer the advantages of improved stability, targeted delivery and controlled release of APIs in vivo, which can reduce drug burden while enhancing efficacy. Poly(lactic-co-glycolic acid) (PLGA) is amongst
Dramatically distinct tropism and transduction efficiencies of AAV serotypes following subconjunctival injection
Instead of relying on traditional drug modalities, gene therapies rely on delivery of nucleic acids into patient’s cells to prevent, slow, stop or treat diseases. In the past decades, gene therapy has been broadly studied in pre-clinical
Stem cells and stem cells conditioned medium for inflammatory bowel disease treatment
Inflammatory bowel disease (IBD) is a complex of pathological processes occurring in the intestine. Chemically induced IBD in rodent usually used for study of drug therapy efficacy. Mesenchymal stem cells (MSC) was used as alternative method for
FLYWCH1 is a novel transcriptional repressor for the cancer-causing Beta-catenin
There is no doubt that cancer is a devastating disease. However, restraining the cancerous cells from spreading throughout the body (invasion) will make it easier to control and possibly cure cancer. β-catenin is one of the proteins
Local immunomodulation by Jagged-1 for islet graft acceptance
Type 1 diabetes is a chronic autoimmune disease with a high economic burden worldwide ($327 billion in 2017). Although transplantation of pancreatic islets is a promising approach for treatment of type 1 diabetes mellitus, the engraftment efficiency
Aesthetics
Our lives are full of aesthetic experiences. From the taste of coffee in the morning till a last glimpse at the stars before falling asleep, we constantly evaluate what we perceive with our senses. That is the
Confronting the paradox of irrigation efficiency
Why does the term ‘efficiency’, when applied to the irrigation sector, cause such confusion and misunderstanding? And why is promotion of increased irrigation efficiency likely to hinder achievement of the Sustainable Development Goal (SDG) 6: ‘Water for
Write my paper for me service: an effective tool to cope with academic difficulties
To be a student is not always fun. The greater part of students faces various problems. The most common of them is a lack of money, too complicated curriculum, disability to find a common language with other
Assessing extreme weather events, vulnerability, and the impacts on human wellbeing in Latin America
The increased occurrence of extreme climatological, hydrological, and meteorological events (EWEs) and Climate-sensitive Disasters (CSDs) (e.g. floods and storms) in Latin American countries (LACs), and their primary impacts on human wellbeing should be considered carefully. This requires
Moisture slows down propane diffusing through rocky pores
Natural gases emanate from the ground passing through tiny pores and fractures in silica rich rocks. These tiny pores alter the behavior of the gases passing through them. To understand the fundamental processes involved in gas migration
More Paleolithic-like lifestyles and diets associated with lower colorectal cancer risk
Colorectal cancer (CRC) is the second leading cause of cancer deaths among women and men combined in the United States. CRC incidence (i.e., the rate of new diagnoses) varies about 20-fold across countries. The incidence among immigrants
What happens inside the eye: fluid forces under physiologic movements
The vitreous is a gel-like structure that completely fills the posterior part of the eye. Doctors inject drugs directly inside the vitreous to cure sight-threatening diseases like age-related macular degeneration. These are relatively new therapies; few is
High potential polymer carriers to enhance antibiotic efficiency in bacterial biofilms
Cystic fibrosis (CF) is a frequent genetic disease resulting in chronic and difficult-to-treat pulmonary infections and inflammation that needs a lifelong treatment with aggressive antibiotic therapy by oral, intravenous or inhaled routes. The most abundant bacterial species
Associations between mathematics development and visuo-spatial perception in children with cerebral palsy
Previous research has suggested that children with cerebral palsy (CP) have difficulties with visuo-spatial perception. We wanted to find out if there was an association or relationship between the children’s visuo-spatial abilities and the development of their
It’s Time for Multimodal Biometric Verification. Here’s why
If you have ever watched one of the Mission: Impossible movies, then you’ve definitely seen biometric verification in action. A ton of characters in the franchise have used their eyes, voices, faces, and fingerprints to access a
Complexity and behavioral diversity in evolving populations under uncertainty
Evolutionary Game Theory – an application of game theory to evolving populations in biology, introduced by Maynard Smith and Price in 1973 – provides a mathematical framework describing dynamics of competition and strategic behavior according to Darwinian
3D-printed chitosan scaffolds for the improved in-vivo wound healing in diabetic rats
In the tissue engineering context, fabrication of porous three dimensional (3D) printed chitosan (CH) scaffolds for skin tissue regeneration and their behavior in terms of biocompatibility, cytocompatibility and toxicity toward human fibroblast (Nhdf) and keratinocyte (HaCaT), was
Should we insert wearable tech into our bodies?
Posted by Santi Bolivar Humans have always looked for ways to become stronger, smarter, and more resilient. In fact, Elon Musk says that’s exactly what all types of technology give us. Our smartphones enhance our mind just
