Author Archives: karen

May-Thurner Syndrome – a rare cause of leg pain and swelling

In this case, a 75 year-old female presented with painful swelling in her left leg shortly after stents were placed in her iliac arteries, which are blood vessels in the upper thigh that allow blood to flow

Fat and genes: can they predict stroke?

The modern way of life has led to an unprecedented increase of diseases that affect the well-being of our arteries, including high blood pressure, high lipids, diabetes and obesity. These diseases promote atherosclerosis, which means the deposition

Functional behavior of neuronal networks interconnected through electrical synapses

Gap junction (GJ) channels, which allow direct transfer of electrical signal and exchange by metabolites between cells, are formed of 21 member of connexin (Cx) protein family in humans. Hundreds of GJ channels clustered in junctional plaques

Importance of diagnosing spontaneous intracranial hypotension with uncommon clinical presentation

Spontaneous intracranial hypotension (SIH) results from loss of cerebrospinal fluid (CSF), most commonly from a CSF spinal leak, without history of recent surgery, spinal procedure or trauma. Patients typically present with orthostatic headache, i.e. headache upon standing

Acute apical endodontic abscesses: the role of bacteria, geography, and synergy

In conditions of health, the root canal of the tooth is essentially sterile and devoid of the hundreds of microbial species that colonize the oral cavity. When oral bacteria are permitted to access the pulp – whether

Testing a new way to measure the impact of stroke: PRECiS

Cognition helps us think and understand the world. It involves functions like memory, attention, problem-solving, planning, organising and communicating. After a stroke, many people have problems with cognition. These can affect confidence, mood and the ability to

One explanation for why females have more optimal cardiac blood flow compared to males

The myogenic response is defined as that the muscle layer of small blood vessels, called resistance vessels, responds to changing blood pressure (within a certain range) by constricting (smaller vessel diameter) when intraluminal pressure is increased and

Trucker sleep patterns influence safety-critical events

Commercial truck drivers are essential to transporting goods long distances to meet consumer demands. These demands can put pressure on shippers to move goods quickly while keeping costs low, which often puts truckers at risk for insufficient

CCN proteins : A new vista for molecular medicine

The CCN family of proteins is composed of six members playing critical biological roles, both in normal and pathological conditions. The first three CCN proteins discovered were designated Cyr61, Ctgf, and Nov because of the context in

Improving cancer care: Counseling patients on quitting smoking

Given the damaging effects of continued smoking on cancer management and post-treatment survival, all oncology practitioners should provide brief counseling to patients who smoke, encouraging them to quit smoking and referring them to specialized care (i.e. tobacco

Serum osteopontin as a novel biomarker for muscle regeneration in Duchenne muscular dystrophy

Duchenne muscular dystrophy (DMD) is an X-linked muscular disease, affecting boys in principle. It is caused by mutations in the gene coding for dystrophin, a membrane-related structural protein in skeletal and cardiac muscles. The lack of dystrophin

Multi-tasking proteins protect sea urchins from multitudes of pathogens

Antibiotic resistance in bacteria is a deadly problem for human health, yet these pathogens arise and persist due to the misuse and over-prescription of the same classes of antibiotics.  Wouldn’t it be better if there was a

Oxidized cholesterol makes stronger and stiffer cells, promotes blood vessel formation

Atherosclerotic plaques that clog major arteries lead to heart attack and stroke because of the loss of the local blood supply to the heart or to brain tissues. It is also increasingly recognized today that formation and

Do we really know why cardiac surgery is still affected by substantial inflammatory reaction?

Modern cardiac surgery was born in early fifty’s with the use of the heart lung machine. This machine allowed to bypass the heart and the lung, draining the blood from the right atrium, oxygenating and pumping it

How alkaliphiles produce energy to sustain their life under extremely low concentration of proton

Alkaliphiles are defined as microorganisms with optimum growth pH of above 9 (10-9 mol dm−3 H+ concentration).  This means that these microorganisms can grow in environment with one-hundredth times lower proton (H+) concentration than that of neutral

Recent trends in treating kidney stones

Kidney stones are incredibly common in the United States and the prevalence is increasing at a remarkable rate.  In the United States, the chance of a man having a kidney stone at some point in his life

MOF for oxoanion pollutant sequestration

The rapid industrial growth over the past century has led to the increasingly critical problem of effluent treatment which is usually discharged into water streams. In this regard the capture of inorganic pollutants from such streams has

What we have done on arsenic issue in last 15 years in Bangladesh (The Millennium Development Goal period 2000-2015)?

Arsenic is well known poisonous chemical component which naturally found in underground from soil, and water. Bangladesh is one of the country where certain area of its ground water has been contaminated with arsenic. Majority of its

More equal sexual arousal between the sheets

The cosmetic and functional results of creating a vagina by use of penile and scrotal skin in male-to-female transsexuals are, in general, satisfactory. One of the goals of creating a vagina is to create tactile and erogenous

Atom tunneling in chemistry

While macroscopic objects from everyday life follow the classical laws of physics, microscopic objects obey the laws of quantum mechanics. These quantum objects, such as light (photons), electrons, and atoms, show characteristics of particles as well as