Category Archives: Research
Is there a link between hematologic malignancy and ischemic optic neuropathy?
Ischemic optic neuropathy is the most common acute optic neuropathy in patients over the age of 50. The ischemic injury may be localized to the anterior part of the optic nerve – anterior ischemic optic neuropathy (AION),
Back pain research: Skirting around the edges?
Low back pain is the leading cause of disability worldwide. The fact that it is seldom possible to identify a specific nociceptive cause is thought to be a major barrier to its successful management. At the same
How the seasnake lost its bands
Across Europe, the Industrial Revolution of the early 1800s blackened the trees with soot. That shift in color exerted strong evolutionary pressure on many species of insects that were camouflaged against natural tree-trunks but very obvious (to
Asymmetric vestibular stimulation reveals persistent disruption of motion perception in unilateral vestibular lesions
A unilateral vestibular lesion (UVL), typically due to acute vestibular neuritis, induces vertigo, imbalance, asymmetry of the vestibule-ocular reflex (VOR) and problems with the perception of self motion. This study examined the question of whether the disruption
Lower TSH and higher free thyroxine predict incidence of prostate but not other common cancers
The pituitary gland signals production of thyroid hormones by the thyroid gland through secretion of thyrotropin (TSH). There are two types of thyroid hormones produced by the thyroid gland. These include thyroxine (T4) and tri-iodothyroinine (T3). These
Biomarker panel for detecting early pancreatic cancer
Pancreatic ductal adenocarcinoma (PDAC), the most prevalent type of pancreatic cancer, is the fourth leading cause of cancer-related deaths in the USA. Most of the PDAC patients are diagnosed at an advanced stage of disease and their
PREMM: A mobile application to drive your own hereditary cancer prevention
In the recent publication, ‘Community Practice Implementation of a Self-administered Version of PREMM1,2,6 to Assess Risk for Lynch Syndrome’, Dr. Luba and colleagues at the Monterey Bay GI Consultants Medical Group in Monterey, California, present the use
New psychoactive substances and drugs of abuse inhibit neuronal activity
New psychoactive substances (NPS), also known as ‘legal highs’, ‘bath salts’ or ‘research chemicals’, appeared on the drug market around a decade ago. Even though they account for only a small proportion of the market, NPS encompass
SERS substrates by vacuum-free dealloying of Au-based metallic glass ribbons
Plasmonics has become an important photonic device due to the advancement of fabrication technologies in recent decades. It has many applications including solar cells, nonlinear optics, metamaterials, photocatalysts, and surface-enhanced Raman spectroscopy (SERS), etc. Among those, SERS
Calcium ion by replacing magnesium ion unravels an unexpected role for the mitochondrial F1FO-ATPase
The F1FO-ATPase/synthase is universally known as a complex enzyme machinery which, embedded by the FO portion in the inner mitochondrial membrane and the catalytic F1 sector protruding in the matrix, matches the transmembrane proton flux which occurs
Costly reputation maintenance behavior is a building block of human cooperation
Reputation plays a crucial role in human cooperation. This is because people tend to cooperate with someone with a good reputation. For example, if Anne knows that Bob helped Cathy before, and Bob is now in need,
Better implants with stem cells
Prosthetic implants are used day-to-day to treat edentulous people and patients in need of skeletal reconstructions. The history of prosthetic dental implants dates back thousands of years, with the early civilizations using seashells and stones to replace
Oriented attachment determines a shape of nanoparticles in gas phase
Until two decades ago, the process of crystallization from a supersaturated solution was assumed to proceed exclusively by molecule-by-molecule addition. However, some recent pioneering theoretical and experimental studies have revealed that crystals can grow by some other,
Acute ischemic stroke: An urgent call for help and funding!
In humans, acute ischemic stroke is the primarily result of a blood-clot that moves toward the brain and blocks one or more important blood vessels that supply blood, oxygen, and nutrients to brain tissue (Fig. 1), causing
Genital gender-affirming surgery: a history from the shadows to the forefront
Gender dysphoria is characterized by a discrepancy between an individual’s gender at birth and the gender with which they identify themselves. Gender-affirming surgery encompasses a variety of procedures that aim to alleviate gender dysphoria. These are broadly
Open storage of sub-soil river water leads to significant change in water quality
Reservoirs and dams are created for catering to the need of agriculture, industries, domestic etc as a continuous reliable source of water. Among other uses, power plant (PP) cooling water system (CWS) needs reliable and continuous supply
How the mitochondrial F1FO-ATPase can be chemically switched on/off and serve as drug target
The mitochondrial F1FO-ATPase is well known to play the main role in synthesizing most of ATP, thus providing energy to living cells under aerobic conditions. However the enzyme complex can also work in reverse and split ATP
Early sepsis does not stimulate reactive oxygen species production and does not reduce cardiac function despite an increased inflammation status
Sepsis is due to bacterial infection. If it is sustained for several days, it can trigger severe abnormalities of cardiac function which leads to death in 50% of cases. This probably occurs through activation of toll-like receptors
Varity of phase separation patterns induced by a propagating trigger
A pattern is formed when a phase separation in two component mixtures occurs. A bicontinuous network pattern is formed when the concentration of the two phases are symmetry to the phase separation line. Meanwhile, when there is
Can castol oil safely induce labor at home in postdate women?
Pregnancy that extends beyond 40 weeks gestation is termed a post-date pregnancy. There are many maternal and neonatal complications that arise from post-date pregnancies, such as cesarean section, fetal distress, or even intrauterine fetal demise. There are
