Tag Archives: drug delivery
Lipid nanoparticles loaded with CpG oligonucleotides exert an antitumor effect via immunomodulation
Since the emergence of immune checkpoint inhibitors (ICIs), cancer immunotherapy has dramatically developed. However, its drawback is the low overall response rate to its therapeutic effect. The efficacy of immunotherapy is suggested to depend on the immune
Gas types affect stability of microbubbles and ultrasound mediated brain-targeted drug delivery
Ultrasound (US) is used for clinical diagnosis and therapy. Microbubbles (MBs) as US-contrast agents are applied to detect micro blood flow or specific lesions. Recently, the combination of MBs and US has received much attention for drug
Intracranial injections and animal models: towards understanding and treating human disease
The use of laboratory animals helped us to better understand a myriad of biological processes in health and disease and enabled the development of therapies that effectively cure, or ameliorate life conditions of, millions of people every
Production techniques for the development of sub-micron size polymeric drug delivery formulations evaluated
Polymeric drug delivery formulations containing active pharmaceutical ingredients (APIs) offer the advantages of improved stability, targeted delivery and controlled release of APIs in vivo, which can reduce drug burden while enhancing efficacy. Poly(lactic-co-glycolic acid) (PLGA) is amongst
Should we think that neem gum polysaccharide and their semi-synthetic derivatives can be utilized as carrier for nanoformulation
One of the major concerns related to the newly synthesized drug is poor water solubility, which seems to be a major concern for the pharmaceutical manufacturer and also a rate limiting step in the bioavailability. In this
International Conference and Exhibition on Pharmaceutics & Novel Drug Delivery Systems. Osaka, Japan. September 09-10, 2019
Cientific Group is overpowered to declare its absolute first “International Conference and Exhibition on Pharmaceutics and Novel Drug Delivery Systems”. Pharma Conferences hung on September 09-10, 2019 at Osaka, Japan. Pharmaceutica – 2019 gives a general stage
International Conference on Pharmaceutical Sciences and Drug delivery. Milan, Italy. November 18-19, 2019
Theme: Optimizing Research reforms of the Pharmaceutical Industry. We cordially invite each and every interested and enthusiastic participant from all over the world to take part in the International Conference on Pharmaceutical Sciences and Drug delivery, at
Diving into the mucus – PEG micelles for oral delivery
Swallowing a pill of paracetamol for headache is fast and easy. The drug can be administrated at a desired time and location without any pain or assistance. Such is not the case for biological drugs like insulin,
Electrifying drug delivery
Most patients with chronic illnesses are treated with oral drugs and injections. These delivery methods are plagued by low drug efficacy and nonspecific side effects. In addition, studies estimate that as high as 60% of the patients
Unmet clinical needs in the treatment of systemic fungal infections. Reformulating repurposed drugs such as amphotericin B
A recent increase in the frequency of fungal infections has led to a higher number of fungal species that can cause these pathologies, as well as a decrease in the number of effective treatments against them due
The road to new aortic valve disease treatment: Innovations in 3D models and drug delivery
Calcific Aortic Valve Disease (CAVD) resulting in aortic stenosis is a common heart disease that affects 25% of people over 65 years old, causing 17,000 deaths per year in the USA. The aortic valve regulates blood flow
Manipulating a single microtubule by light
A cell is basically a miniature factory, which contains a large number of dedicated protein machines to perform various mechanical functions. For example kinesin is a linear motor protein which transport cargos such as organelles, chromosomes and
Enzymes digestible nanoparticles: a new generation of biodegradable drug delivery nanosystem
Pathologies with high death rates such as cancers may well have found their solutions with the rise of nanotechnology. Nanotechnology is a newly coined word encompassing the application of nanoparticles for all kinds of technological challenges. A
Theoretical design of drug carrying block copolymer micelles
One of the challenges of next generation drugs is the design of target-specific delivery of pharmaceutical agents to the cancerous tumors or diseased cells. Polymer micelles and hydrogels have been traditional candidates for drug-delivery purposes. Poorly soluble
Can a doughnut-shaped molecule help design new drugs?
Some of the most advanced and modern medicines, such as those used in the treatment of cancer rely heavily on their selective, high affinity targeting of cancerous cells in order to be effective medicine. However, some drugs
Diamonds – The doctors’s best friend?!
Most people know about diamonds as jewelry and as the hardest material that can cut nearly everything. It is also known that what makes diamonds unique is the crystalline structure, which is brought about primarily with high
Improving nature’s own communication system to fight cancer
Our bodies are composed of trillions of different cells, which communicate with each other in order to keep us healthy. There are several ways in which messages can be sent back and forth between cells. One of
New systems capable of stimuli-controlled release of drugs
The search for new medical strategies with high therapeutic efficiencies and reduced adverse side-effects remains a challenge for the scientific community. The development of new drug delivery systems (DDS) to generate new solid forms of active pharmaceutical
The right tool for the right job – it is brain surgery after all!
Getting drugs into the brain to help treat cancer or neurological diseases like Parkinson’s or Alzheimer’s is pretty difficult. Generally speaking you can’t just take a pill or get an injection as the brain is protected by
Milk exosomes for drug delivery
The need to effectively deliver drugs to target site has employed a multitude of substances varying from biological to a chemical nature and solid metals for the preparation of tiny drug delivery vesicles called nanoparticles. However, factors
