Tag Archives: tumor

The prognostic value of tumor markers and cytokines in patients with squamous cell cervical cancer

Optimal management of cervical cancer consists of appropriate treatment methods after the precise staging, following detection as early as possible, and the best salvage therapy. Early detection of recurrence, especially at the early stages in cervical cancer

Nanoformulations for cancer therapy

Cancer is a major disease responsible for death in human beings. A lot of research has been performed to develop improved diagnostic tools as well as drugs to treat cancer. Effectiveness of therapeutics in cancerous malignancy is

Over-expression of TRX2 reduces p53-mediated cell death in yeast

The p53 gene is a human tumor suppressor which is involved in cell cycle regulation. It has an efficient ability to inhibit cell proliferation, by both blocking cell cycle progression and promoting apoptotic cell death in order

Helpful tool for the characterization of cancer

Follicular lymphoma is a sort of blood cancer and among the most frequent subtypes of indolent (painless) lymphomas. Most patients are diagnosed very late, when the illness is in an advanced stage. The origins of the tumor

Reducing blood loss in brain surgery with extracranial early devascularization techniques

The anatomical region located under the frontal lobes of the brain, just above the eyes and the nose is called “anterior skull base”. The most common tumors involving this region arise from the soft tissue layers that

Cell division drives collective motion in cell monolayers

Cell division is essential to morphogenesis, tissue spreading, and tumor invasion. In particular, the hallmark of tumor invasion is the ability of cancerous cells to divide in extreme numbers. Our findings on the effect of cell division

Using nanotechnology to outsmart pancreatic cancer

Cancer is a versatile disease and makes use of complex cellular signaling networks to defend itself against a host of treatments. Pancreatic cancer in particular has proven challenging with tenacious resistance to DNA-damaging chemoradiation. Malignant cells disobey

Rare breast tumor cells in lymph nodes are enough to impact on cancer cure

Early detection of breast cancer leads to essential cure of the vast majority of patients, through surgery and associated therapies. However, severe outcomes can be observed even among disease cases currently categorized as low-risk. Approximately 15% of

Smart tumor suppression via intracellularly delivered drug

With the rapid metabolism of tumor cells, the microenvironments of tumor tissue and cells present acidity, while the pH maintains at about 7.4 in normal extracellular matrices and blood. In detail, the extracellular pH in tumor tissue

Trafficking and signalling from the endosome regulate blood vessel formation in the lung

The formation of new small blood vessels is essential during development and as a repair mechanism in disease. In the lung, blood vessel formation is altered in diseases such as severe bacterial infection and tumour spread. The

Deposition of aluminum and iron in benign bone tumors (exostosis)

An exostosis is an outgrowth of new bone from the surface of a bone into the muscles; it is a frequent benign tumor in children. An exostosis causes discomfort and chronic pain, depending on its size and

Locoregional treatment versus no treatment of the primary tumour in metastatic breast cancer

Stage IV breast cancer is the state in which the cancer has spread to distant sites , for example , the brain, liver, lung, bones. Treatment for stages I to III of breast cancer include surgery, chemotherapy