Yearly Archives: 2015
The effect of dehydroepiandrosterone in different stages of osteoarthritis
Osteoarthritis (OA) is likely to become an increasing burden in the coming decades. Current medications for OA, including nonsteroidal anti-inflammatory drugs (NSAIDS), steroids or viscosupplementation provide only symptomatic improvements. The major disadvantage of all current treatments is
Genome studies of a soil bacterium, a potential candidate for removing arsenic from contaminated water
Worldwide various human activities such as mining, chemical industries, use of arsenic-based pesticides, and natural occurrences result in contamination of soil and water with heavy metals and cause severe environmental and health problems. Millions of people are
Who is going to do well on anticoagulants?
Anticoagulants are very good at preventing recurrent disease in patients with deep vein thrombosis and pulmonary embolism. This is important because venous thrombosis frequently causes long-term complaints such as pain, edema, fatique and dyspnea. Moreover, 4% of
Trifluoromethylthiolation of aliphatic electrophiles
As one of the most advanced technologies currently available for studying in vivo molecular interactions, positron emission tomography (PET) is a functional imaging technique that can produce a three-dimensional image of functional processes in the body. It
Invest in health at work: an economic challenge
Almost one third of EU citizens report that work affects their health. When asked how work influences their health, 25 % of Europeans declared work to be pathogenic. Conversely, only 7 % reported work to be positive
Where is the pacemaker in the womb?
In our body, we have several types of muscles to perform many types of activities, such as moving our skeleton (i.e. walking), pumping our blood around (heart and vessels) or absorbing and propelling our food in the
How many species of hakes inhabit Argentine and New Zealand waters?
Hakes belonging to the Genus Merluccius are one of the most heavily exploited fishes worldwide. In Argentinean waters, merluccids have been one of the most valuable fishery resource, representing about 40% of the total fish catch in
A novel approach for the treatment of Juvenile Idiopathic Arthritis and possibly other autoimmune diseases.
Juvenile Idiopathic Arthritis (JIA) is a leading chronic autoimmune disease in children that can result in severe disability, pain, and loss of quality of life. Similarly to what is found in other autoimmune diseases, the immune-balance in
How Panax ginseng prevents pneumococcal diseases and sepsis
Panax ginseng C.A. Meyer (P. ginseng; common name Korean ginseng) is one of the most popular herbal medicines in Korea and Asian countries. P. ginseng is very well known as a potential immune-modulator on various cancer diseases.
Stranded cetaceans as sentinels for those living in the open sea
Cetacean strandings, coupled with the study of their causative factors, are a matter of rapidly growing scientific interest and debate. Within such context, “beached” cetaceans undoubtedly represent a crucial source of “vital informations”, provided that dolphins’ and
Stress tolerance in plants is controlled by a “master regulator” of chloroplast protein import
To achieve food security by meeting the needs of an ever growing human population, which could reach near 10 billion by 2050, large increases in crop yields will be essential. Environmental stresses, such as drought and salinity,
Trafficking and signalling from the endosome regulate blood vessel formation in the lung
The formation of new small blood vessels is essential during development and as a repair mechanism in disease. In the lung, blood vessel formation is altered in diseases such as severe bacterial infection and tumour spread. The
Combining different antibody flavors to improve cancer therapy
Our immune system is specialized at identifying ‘foreign intruders’ (pathogens) or virus-infected cells inside the human body. This can be achieved by antibodies (immunoglobulins) that circulate in our body and are able to bind targets with high
Diabetic peripheral neuropathy
Diabetic peripheral neuropathy is nerve damage caused by diabetes. Population-based studies have suggested more than half of patients with either type I or type II diabetes will develop neuropathy, and as much as 30% of those manifestations
What do we breathe? A study of particular matter exposure and deposition in the human respiratory tract
Have you ever thought about the diameter of a single hair from your head? It is somewhere between 50-70 µm. (micrometres, or thousandth of millimetres) wide. Small, isn’t it? Well, now think about liquid or solid droplets
GLI mutations in patients with Hirschsprung disease
Hirschsprung (HSCR) disease (congenital megacolon) is one of the more common birth defects. It is a global problem but is particularly prevalent in Asia, affecting 1 in 3000 babies. These babies suffer from severe constipation and intestinal
Weather predictions of tick bite risk
A walk in the park can be an uplifting experience. It can also turn into a nightmare if the outdoors are filled with blood hungry ticks. The newly published research shows that weather conditions, particularly temperature, can
A novel 18F-azido click agent and their applications in PET imaging
Positron-emission tomography (PET) is a non-invasive molecular imaging technique that is used to study and visualize in vivo physiology by the detection of positron-emitting (radiolabeled) compounds. Fluorine-18, represented by symbol 18F, is the most widely used element
The vicious cycle in liver that fuels the obesity diabetes pandemic
Experimental obesity is readily produced by dietary excesses of fats or carbohydrates and involves an initial increase in glucose production by the liver with subsequent increases in blood insulin levels, i.e., an insulin-resistant state. In turn, elevated
Gene expression changes underlying prostate cancer metastasis
Prostate cancer is one of the most common cancers among men. The American Cancer Society estimates that there will be 220,800 new cases of prostate cancer in 2015 and 27,540 prostate cancer related deaths. The National Cancer
