Monthly Archives: June 2016
Can a doughnut-shaped molecule help design new drugs?
Some of the most advanced and modern medicines, such as those used in the treatment of cancer rely heavily on their selective, high affinity targeting of cancerous cells in order to be effective medicine. However, some drugs
ACT for a “self” relieved of the burden of pain
Chronic pain is often defined as any pain lasting more than 3 months, and may arise from an initial injury, an on-going illness, or no clear cause. The change and suffering wrought from chronic pain could fundamentally
Keeping Score: dermoscopy for the diagnosis of melanocytic lesions
Among people at high risk for melanoma, skin cancer screening is valuable for early detection of a new malignant melanoma. When dermatologists identify a suspicious lesion, a biopsy is performed and the removed skin sample is sent
Differential courses of delay discounting in mild cognitive impairment and Alzheimer´s disease
People prefer to receive a reward rather sooner than later, which means that people put a smaller value on a reward they have to wait for (= delay discounting, DD). But when people get to choose between
Effects of Cadmium on amphibians
Cadmium is a toxic metal for living organisms. It causes abnormal fetus development, cancer, DNA mutations; it impairs growth, and compromises the functions of the reproductive, respiratory and endocrine systems. Cadmium enters the aquatic system through industrial
Crafting and grafting of new cells to treat epidermolysis bullosa
Epidermolysis bullosa (EB) is a disease that causes the skin to become extremely fragile, which leads to the formation of blisters. Depending on the form the disease takes, ranging from relatively mild to terribly severe, the blistering
Can antioxidants benefit the diabetic kidney?
People who have diabetes are at high risk of developing kidney disease that may require dialysis or transplantation. This has been known for a long time but there is still a need for new ways to prevent
Coronary ostoplasty for congenital atresia of the left main coronary artery ostium in a teenage boy
Coronary artery abnormalities are reported as the third largest cause of sudden death in young athletes. Because patients usually do not have any apparent abnormality on medical examination, it is difficult to detect this before some events.
Tree hole mosquitoes in Western and Eastern Ghats, Tamil Nadu, India
Mosquitoes are most dangerous tiny insects killing 7.25 million people in the world annually. They serve as carrier of deadliest pathogens causing dengue, malaria, chikungunya, filariasis, West Nile virus, zika, Japanese encephalitis, etc. Nearly everyone knowns that
Why women with early stage breast cancer don’t complete their chemotherapy treatment?
Breast cancer is a leading cause of cancer death among US women. For women with early stage breast cancer (stages I and II), completing chemotherapy after surgery can increase survival. Despite this proven benefit, some women do
Alcohol problems in India
Despite low prevalence of alcohol use in India, alcohol use disorders are prevalent and persistent among men in Goa, India. The finding is reported in a study conducted by the Sangath Institute (India) in partnership with the
New insights into the interaction of centrin with Sfi1
The Sfi1 protein is localized to the centrosome that is also called the spindle pole body in yeast. Thus, Sfi1 is involved in the centrosome behaviour. As a consequence of the DNA replication, the centrosome is also
Treatment for age related loss of near vision: Raindrop near vision inlay one-year clinical results
Presbyopia is an ocular condition associated with age related loss of near vision. The eye loses the ability to focus well on near objects due to the hardening of the natural lens. It affects billions of people
Use of a web-based dietary assessment tool in early pregnancy
It is now known that diet during pregnancy can influence long-term health of the offspring. However accurate dietary intakes are difficult to obtain. For example, mis-reporting of energy intakes by the respondent and inaccurate estimation of portion
What does “I need to breathe some pure air” really mean?
When people live in urban environments, getting away from the city, the noise and the smog, becomes some sort of “physiological need”. This is also true in exciting places like Barcelona. But, do we really have reasons
Cupric ions enhance the radical scavenging capacity of cysteine-derived antioxidants
Free radicals are chemical species with one or more unpaired valence electrons. This feature predetermines a high reactivity of free radicals that may initiate a variety of chemical processes such as explosions or polymerizations. Free radicals play
Delivering the intended drug: Adding surfactant to IV administration fluid prevents protein particles
Each year, over 12 million people are diagnosed with cancer, and many others are impacted as a family member or close friend. No matter how one is affected, cancer causes pain, heartbreak and suffering. Scientists at Bristol-Myers
How good are we at memorizing and recognizing voices?
Thanks to modern technology, we do not experience many situations in which we are required to recognize the voice of a familiar person calling us at the phone; we know who we are speaking to because it
A novel method of edema fluid drainage in obstructive lymphedema of limbs
Human tissues contain tissue fluid. This fluid originates from blood plasma. Plasma water, proteins and nutrients are filtered to tissues from blood capillaries and spread around the cells. Cells incorporate from tissue fluid what is important for their
