Category Archives: Research
Obesity fuels breast carcinogenesis: What is the molecular basis?
Excess body weight is associated with the primary risk of 13 distinct cancers and is generally considered a poor prognostic indicator for patients diagnosed with a variety of malignancies. Obesity is increasingly recognized as a risk factor
The longest single crystal structure confirmed azaacene derivative: one step forward large conjugation molecules
Organic semiconductors are supposed to be the next generation semiconductors, which shows many great advantages over silicon. For example, their devices are easier and cheaper for fabricating and can be flexible. Their variable molecular structures can be
Linear-shaped and ring-shaped Re(I) multinuclear complexes work as highly photofunctional molecule
Octahedral six coordinated rhenium(I) (Re) diimine complexes with three carbonyl ligands show long-lived and strong room-temperature luminescence, attributed to a low-lying triplet metal-to-ligand charge-transfer (3MLCT) excited state. Tunability of their properties emerges from synthetic versatility and therefore
More intensive anticoagulation is associated with a lower stroke risk after elective cardioversion in atrial fibrillation
Atrial fibrillation (AF) is the most common arrhythmia of the heart and elective cardioversion (ECV) is a common procedure in converting AF to normal sinus rhythm. AF carries an increased risk for stroke and a substantial portion
What response of skin blood flow in hindlimb does electrical stimulation of forelimb induce?
The nervous system includes the central nervous system (CNS) and autonomic nervous system (ANS). Abundant evidence exists to show that structures and functions of the CNS in humans are bilaterally asymmetrical. The best known example of brain
Molecular transformation from monocyclic to chiral tricyclic scaffold by using organonickel catalyst
Waste-free (or -minimized) molecular transformations from chemical feedstocks to complex structures is a state of the art, as it provides a cost-effective, environmentally benign and practical route to natural products as well as active pharmaceutical candidates (API).
Which is the best way to intraoperatively detect an electrode array misplacement in cochlear implantation surgery?
Cochlear implantation (CI) is a worldwide well-known procedure for the treatment of severe to profound hearing loss. New surgical techniques and technological upgrades in the past years have helped to decrease complications of this procedure, but they
A combination of medical therapy and liver transplantation save children with acute liver failure
Acute liver failure (ALF) in children is defined as a severe impairment of liver function characterized by biochemical evidence of acute liver injury, coagulopathy (INR ≥2.0) regardless of the presence of hepatic encephalopathy (HE) and no history
Effect of the new hybrid 3,5-dipalmitoyl-nifedipine on the ischemia / reperfusion simulation
The myocardial ischemia process is a global health problem. Damage after myocardial ischemia and reperfusion (I/R) is the leading cause of morbidity and mortality globally. Hypertensive patients are most affected by I/R. This work investigated the acute
Cyclists burn more fat with New Zealand blackcurrant – dose responses
Fruit and vegetables are made from multiple constituents and appropriate daily consumption provides positive health benefits. The bright colouration of fruits and vegetables comes from the polyphenol content and these in part are attributable to the health
Bandaid immunization to prevent ear infections
Almost every child will develop an ear infection and unfortunately, some children will have seven or eight before their first birthday. These chronic infections can result in language, developmental and educational delays, all factors with long-term consequences.
Three-dimensional computed tomographic volumetry precisely predicts the postoperative pulmonary function
Surgical resection remains the principal treatment for early stage lung cancer, although new chemotherapeutic agents and molecular-targeted drugs have been developed. In order to conduct pulmonary resection safely, it is necessary to ensure that the patient’s postoperative
The lysosomal enzyme cathepsin D as novel therapeutic target for non-alcoholic steatohepatitis
The decrease in physical activity combined with increased caloric intake has led us to a global obesity epidemic. Obese patients can develop metabolic syndrome (MetS), which is a term used to assess the risk of a patient
Cyanobacteria: microbial factories for drug discovery
Cyanobacteria, the only prokaryotes that perform the oxygen-producing photosynthesis, are ancient organisms that shaped the atmosphere of our planet. In colonizing most waters and soils, where they face various environmental challenges and competition with many biological organisms,
Oxidative stress sensitivity of cancer cells could be altered by plasma membrane status
Oxidative stress is defined as “A status that the balance between the oxidation reaction and the antioxidant reaction is lost in our body, and that the oxidation state is dominant.” Oxidative stress is generally adverse for our
Should repetitive behaviours be discouraged in older children with intellectual disabilities?
The importance of considering level of development when understanding the behaviour of individuals with intellectual disability: the case of repetitive behaviours and restricted interests. Children with intellectual disabilities develop more slowly and to a lower ceiling level
Can the chloroplast division machinery be evolutionarily dated back to bacteria?
The chloroplast, known to have originated around a billion years ago, is now one of the most recognizable characteristics of the plant cell. After the engulfment of the ancient cyanobacterium by the eukaryotic host cell, the former
Seminal fluid in infertility: more than just a vehicle
Infertility, which affects 15 % of couples worldwide, is defined as failure of conception despite unprotected sexual intercourse during a period of more than twelve months. Focus on infertility studies has been taking place for decades, however,
