Yearly Archives: 2016

Aggregating anions or cations? H-bonding found to trump electrostatics in ionic liquids

Two of the most persistent and vexing conceptual problems of modern physical chemistry concern (i) the fundamental nature of the hydrogen bond and (ii) the molecular-level structure and dynamics of condensed liquids, which H-bonding often dominates. In recent years,

Increasing the cells adhesion to silk meshes: first step towards cell-based therapy for hernia repair

Recent studies in the field of tissue engineering have demonstrated that combining cells with meshes prior to implantation successfully enhanced hernia repair. The idea is to create a biologic coating surrounding the prostheses with autologous cells, before

Multiple tasks for the c-ring of the F1FO-ATP synthase

The F1FO-ATP synthase is the only enzyme in nature endowed with bi-functional catalytic mechanism of synthesis and hydrolysis of ATP. The enzyme complex is hosted in the inner mitochondrial membrane in eukaryotes and in the plasma-membrane in

Heart and blood pressure adverse effects of phenytoin

Phenytoin is an effective antiepileptic drug which is used for many years in the treatment of epileptic seizures. Whereas its oral form is used for the long-term treatment of epilepsy, the intravenous form – the injection into

Tapping neurotransmitters from neurons to investigate their involvement in brain function

To tap neurotransmitters and neuromodulators from brain neurons of anaesthetised rodents, a guide cannula is stereoractically inserted. Into a distinct brain structure. Few days after surgery the stylet of the guide cannula is replaced by a double-walled

Necessity of global consensus for implementing new initiatives for treatment of aluminum phosphide poisoning

Aluminum phosphide (ALP) is an agricultural pesticide that is used worldwide to kill pests and rodents. It is effective and cheap pesticide that make it readily available especially in developing countries. Its global attention arises from the

Research from animal learning studies may help the elderly to follow medical recommendations

Adherence to treatment is how clinicians refer to the degree to which patients follow medical recommendations, and it is fundamental to improving health and quality of life. Lack of adherence to treatment may have dramatic consequences not

Belching: How does it work?

The belch seems like a simple rapid act with no clinical significance, but many studies suggest otherwise. Although most of the belch response occurs over a period of less than two seconds, the belch is actually composed

What are new traits of Si-rhodamine self-assembly in the excited state?

‘In unity there is strength!’ This is also true in the molecular world. Nowadays, “self-assembly”, composed of a large number of one or multiple kinds of small molecules, has attracted considerable attention. That is because special traits

Salt marsh restoration reduces mercury methylation

In this paper we describe analysis of mercury in sediment cores collected from an area of land behind a dyke one year before, and one year after, it was intentionally breached as part of a managed retreat

Look after your compost—it’s more than garden fertiliser

Biologists look upon a pile of compost first of all as an extraordinary habitat of a wide range of different organisms: a microcosm of its own within the garden landscape. Gardeners in Europe are proud of “their”

Hormetic use of stress in gerontological interventions requires a cautious approach

Hormesis is a biphasic dose-response pattern in which the response at low doses is opposite to that at higher doses. According to the hormesis concept, a small dose of a potentially harmful agent can exert a beneficial

How plant virus hides from the host cellular degradation machinery

The main goal of obligatory viral parasites is to create the perfect environment for its multiplication. Therefore, the first step is to avoid degradation by the host cellular degradation. Tomato yellow leaf curl virus (TYLCV) is not

Melatonin and serotonin in psychiatric and brain disorders

Melatonin is well known as a treatment for jet lag, being naturally released by the brain when we close our eyes to go to sleep. However, recent research shows that melatonin is released by many, if not

Postgraduate studies (1978-1985) at the Medical School, University of Tuzla, Bosnia and Herzegovina

The Medical School (Medicinski fakultet) in Tuzla, founded in 1976, initiated post-graduate studies program in 1978. The aim was to train future medical faculty for scientific research in pre-clinical and clinical disciplines. Most participants were physicians who

Rare disease day; 500 years ago

A rare disease is a life-threatening or chronically debilitating condition with a very low prevalence. Several institutions such as Food and Drug Administration (FDA), European Medical Agency (EMA) and Therapeutic Goods Administration (TGA) have put in place

Towards a nuclear weapons free world

The dream of a world without nuclear weapons has come a little closer to reality over the past three years, thanks to a renewed focus on the catastrophic humanitarian impacts of these worst of all weapons. Beginning

Another prince awakened Sleeping Beauty?

Tumor suppressor genes are one of the body’s defenses against uncontrolled growth of tumor cells. When these genes are ‘silenced,’ or prevented from doing their work, the abnormal cells grow unchecked, usually with fatal consequences to the

How cells crawl… that’s right, crawl

Within our bodies, every cell must crawl – some only a few millionths of an inch, while others, like nerve fibers, must make their way from the spinal cord to the tips of our toes. The ability

Recovery after brachial plexus surgery continues for longer than previously thought

Brachial plexus injuries (BPIs) are severely debilitating injuries in which the nerves exiting the spinal cord at the level of the cervical and upper thoracic spine are damaged. Because these nerves power the musculature of the upper