Yearly Archives: 2017
Strain-specific growth of gut microbiota modulated with carbohydrate-rich-diet is relevant to host health
A growing number of studies have revealed that reversal of intestinal microbial dysbiosis via dietary intervention provides promising benefits to our health. Manipulation of gut microbiota to achieve optimum health benefits is attractive but realizing it precisely
Spiders that pretend to be leaf veins
Daddy longlegs spiders (Pholcidae) are ubiquitous guests in houses around the world and thus known to most people. However, the bulk of the family’s currently 1,600 known species are confined to tropical forests, where they have evolved
Next generation nanomaterials with potential “track and kill”strategy against cancer
It is a paradox that cancer is by far the leading subject of research for scientists all over the world and still it remains to be the most dreadful disease to the mankind. A cancer patient’s treatment
Absolute configurations established for persistent organic pollutants DDT and DDD
Polychlorinated hydrocarbons such as hexachlorocyclohexane, hexachlorobenzene, heptachlor and chlorodane have long been known as effective and durable pesticides. Dichlorodiphenyltrichloroethane (or 1,1,1-trichloro-2,2-bis(chlorophenyl)ethane, DDT) has also been used widely and is still used in a few countries to control
Measuring small molecules for nutrition research?
Metabolomics is the study of small molecules that are present in biological samples. These small molecules include amino acids, fatty acids, organic acids and sugars, and are referred to as metabolites. These metabolites reflect the downstream activity
How plants transmit signals through alternate routes during stress conditions? CBL-CIPK mediated calcium signaling
One of the main characteristics of a plant life is sessile nature. Plants counter this frailty by evolving intricate and fast signaling system that can help in transferring stimuli at a very high rate. The phytohormone ABA
Understanding the mode of action of lynamicin D
Bisindolyl alkaloids represent a large family of natural products that exhibit potent and diverse biological activities such as anti-inflammatory, antimicrobial, antiviral and antitumor. Some of these secondary metabolites are currently evaluated in clinical trials for the treatment
Reversibility of Aβ oligomer neurotoxicity: Insights into the treatment of Alzheimer’s disease
Alzheimer’s disease (AD), the most common neurodegenerative dementia disorder, causes memory impairment and other cognitive deficits. AD is neuropathologically characterized by senile plaques and neurofibrillary tangles, which are composed of amyloid β-protein (Aβ) and phosphorylated tau proteins,
Cigarette butts processing into cellulose pulp
Cigarette butts are composed by cellulose acetate (the filter), cellulose, remaining tobacco, ash and a myriad of toxic compounds added when producing the cigarette or formed during its burning. Because of these toxic compounds, which are persistant
Insulin and brain glucose handling
It has long been known that the brain abundantly expresses insulin receptors in all its major areas, indicating that this vital hormone controlling general glucose metabolism is important for brain function. However, mechanisms of neuro-vascular coupling at
Peculiar pollutants in the Moscow atmosphere in winter period: gas chromatography-high resolution time-of-flight mass spectrometry study
Moscow, Russia is one of the most populated cities in the world, with the metropolitan population reaching 12 million people. Moscow being also an important industrial center has several power plants, multiple industrial factories, waste incinerators, and
Unraveling the enigma of sarcoidosis
Sarcoidosis is an uncommon, genetically-conditioned disease, affecting primarily the lungs. Most cases resolve spontaneously. It is defined by a systemic granulomatous response (SGR) of unknown cause. A granuloma is a distinctive mixed-cellular immune response that reflects failure
Hypoxia mimetic blocks adipocyte differentiation but induces lipid accumulation
Obesity is one of the most immediate health threats in industrialized countries, increasing morbidity and mortality. It is characterized by an excessive increase of white adipose tissue. Adipose tissue is a tissue with high plasticity, having the
2nd Annual Summit on Cell Therapy and Stem Cell Research. Atlanta, Georgia, USA. November 9-10, 2018
Conferenceseries welcomes you to attend the 2nd Annual Summit on Cell Therapy and Stem Cell Research during November 9 – 10, 2018 at Atlanta, Georgia, USA. We cordially invite all the participants from all over the world who are interested in sharing
Abl2 kinase phosphorylates bi-organellar regulator MNRR1 in mitochondria, stimulating respiration
The mitochondria are the well-known “powerhouse” of the cell. Not surprisingly, its functional state is important to other parts of the cell and, conversely, information about the needs of other parts of the cell help determine mitochondrial
Rifaximin for irritable bowel syndrome treatment
Irritable bowel syndrome is generally known as IBS. It is one of the most commonly diagnosed gastrointestinal (GI) disorders which affects about 20% of the adult US population. It is more common in women than men. Physicians
Social Entrepreneurship – applying the scientific method to solving social problems
“The business of doing good” reviews the new textbook “Introduction to Social Entrepreneurship,” a guide for aspiring entrepreneurs who want to use a data-driven approach to making a difference. Based on a course at Harvard, this book
Dinitrosyl iron complexes – natural medicinal form of NO
Everybody knows nitroglycerin – vessel-relaxing medicine effective against angina pectoris. It is a drug working as NO donor – one of the whole family of drugs used to widen our vessels and thus decrease blood pressure. Interestingly,
A dual specificity protein phosphatase and redox homeostasis in plants
Man has been struggling to understand and define life since the day he became aware of it. Innumerable philosophies and findings over the history of mankind together draw the perspective with which we look at life today.
How to optimize pneumonia treatment for the elderly
Can you tell the age of this patient with pneumonia by looking at her chest X-ray (Fig. 1)? Neither can the germ infecting her. And yet there are unique aspects of treatment to know if the patient
