Yearly Archives: 2017
Nuclear shuttling of key methionine cycle enzymes in acute liver injury
Important metabolic enzymes have been classically ascribed to certain subcellular locations, where they perform their well-known function. In the last decades, several technological advances have allowed detection of these proteins in new locations, performing either their known
Injectable hydrogels for microfluidic platforms
Combining biological processes and microfluidic platforms have recently attracted significant attention due to the possibility to fabricate devices for diagnosis of wide range of disorders. Although many immobilization techniques have been established for such systems, developing proper
Type 2 diabetes can originate in utero
Type 2 diabetes (T2D) is considered to be adult-onset disease, since it typically occurred in middle-age and old adults. There is, hovewer, increasing evidence that risk for development of T2D can be influenced not only by adult
A novel sperm structure solve a mystery
How the embryo obtains some of it’s organelles is still a mystery. We know that the nucleus that contains the genetic code comes from the father and the mother via the sperm and egg. We also know
Multifunctional molecular siblings
The interaction of light with matter always ignited the curiosity of researchers and has been a driving force for the discovery and development of new theories, niche technology and novel functional materials. Light emission from an electronically
Recurrent ontogenesis
Flowering plants arose during the Cretaceous, and up to date they count around 235,000 species, representing the largest and most diverse group within the plant kingdom. One of the foundation of their success relies upon the production
20th-century version of an old pathogen. Drug resistant tuberculosis
Mycobacterium tuberculosis the causative agent of human tuberculosis (TB) is consider the most successful pathogen that could infect (2 billion), induce (10.4 million) and kill (1.7 million) a large number of people around the world. Besides this
Is caveolin-1 depletion the key to endothelial cell phenotypic switching in inflammatory vascular disease?
Endothelial cells (ECs) function as the central regulators of blood – tissue communication, controlling the exchange of solutes and immune cells between the vascular and extravascular compartments. In healthy lungs, quiescent ECs express high levels of caveolin-1
Fatigue and torsional resistance of controlled memory and conventional nickel-titanium endodontic instruments
The endodontic field encountered an important breakthrough with the introduction of the nitinol alloy. It offers special mechanical properties like a shape memory effect and superelasticity. Despite of the particular properties of NiTi instruments, they could suffer
Biophysical characterization of the potential role of polar lipids for the stability of tear films
The tear film is a thin structure that covers the surface of the eye. It functions as barrier to evaporation, foreign particles, and bacterial infection. These roles can be primarily attributed to the tear film structure and
Natural aging as a sequential poly-systemic syndrome
A generalized approach to aging is possible based on the General System theory of aging, predicated on the General Model of aging. The fundamental cause of aging is the law of entropy increment in incompletely open systems.
The cation channel of sperm modulates boar sperm motility during capacitation
The male gamete, the spermatozoon, is a highly specialized cell with a trimmed shape, far from the original cells of origin in the testicles. Their primary function is to deliver the paternal gene component of the new
Optimization of fracture healing by improved stabilization
Millions of fractures occur every year worldwide. Most of them heal uneventfully but 5-10 % show delayed healing or non-union. This leads to a great burden for the patients and high economic load for the healthcare system.
Confabulation: What is associated with its rise and fall? A study in brain injury
Confabulation is a relatively rare but debilitating memory disorder. It affects mainly (but not exclusively) brain injury survivors. Patients with confabulations have false memories, for example believing something happened to them which never in fact took place,
What can computational tools tell us about one of the non-structural proteins on Zika virus?
Zika virus has come to global attention even when it only causes mild symptoms to none. Then, why WHO declared a global emergency in 2016? Beside the rapid expansion of the outbreak through Asia and Latin America,
Chirality-induced spin polarization places symmetry constraints on biomolecular interactions
The work examines the fundamental relationship between an electron’s spin and a molecule’s chiral symmetry. The spin of an electron is a pure quantum mechanical property and specifies its intrinsic angular momentum. A common classical analogy for
New Zealand blackcurrant benefits resting cardiovascular function in trained cyclists – dose responses
Fruit and vegetable intake is known to promote health benefits. In part, this can be attributable to the polyphenol content. Anthocyanins are a type of polyphenol and are known to promote health benefits, including positive cardiovascular alterations
Micelle catalyzed 4-nitrophenol reduction
In aqueous solution, molecules with both polar head group and non polar tail (amphiphilic molecules) aggregate i.e., micelles. They absorb/uptake both polar and non polar molecules from solution as a universal host. Thus the horizon of catalysis, detergency,
Serotonin and noradrenaline reuptake inhibitor (SNRI) for chronic musculoskeletal pain may be a red herring?
Dysfunction in the central serotonin and noradrenaline systems cause not only depression but also increased pain sensitivity. Many animal studies indicated that lumbar-intrathecal administration of serotonin and noradrenaline reuptake inhibitor (SNRI) could ameliorate the pain sensitivity which
Annual Congress on Immunology & Immunotechnology. Zurich, Switzerland. September 13-14, 2018
Conference Series invites all the participants from all over the world to attend “Annual Congress on Immunology & Immunotechnology” conference on September 13-14, 2018 at Zurich, Switzerland. The field of Immunology is growing rapidly and its development is making
