Tag Archives: disease
A new drug to improve drug-eluting stents in coronary artery disease
Patients with symptomatic coronary artery disease often receive stent treatment in obstructed coronary arteries of the heart. Even though current generation drug-eluting stents perform very well in the short-term, concerns still exist about their long-term efficacy due
Prevalence of anti-DFS70 antibodies in patients with and without systemic autoimmune rheumatic diseases
The main role of the immune system is to protect the body from a wide range of foreign invaders. In some cases, the immune system recognizes a part of the body as “foreign” and starts to attack
Keyhole heart valve surgery after previous heart transplantation
Advances in heart transplant techniques and medication that control rejection and infections resulted in improved survival and quality of life. These improved long term outcomes are unfortunately paralleled by a variety of associated coronary-, mitral- and tricuspid
Could the humble banana help mitigate diseases?
Musa acuminata, is the scientific name of the wild species of banana that has reinvigorated interest in finding cures for diseases such as cancer, HIV and many more. The wild banana habituates the tropical and subtropical regions
Breathing problems in Parkinson’s disease: a common problem, rarely diagnosed
Parkinson’s disease (PD) is the second most common neurodegenerative disorder after Alzheimer’s disease. It is characterized by bradykinesia (slowness in movement) tremor, rigidity, and postural instability. Potential non-motor manifestations of PD include depression, anxiety, constipation, overactive bladder
TAFRO-syndrome and idiopathic multicentric Castleman disease: An analysis of a new subtype of the rare disease
Castleman disease (CD) is a group of three rare, poorly understood diseases that all involve excessive lymphocyte quantities. All three groups, therefore, are categorized as lymphoproliferative disease. The three groups of Castleman disease share similar lymph node
Overcome obstacles in the treatment of scarred kidneys
More than 10% of the world’s population suffer from chronic kidney disease (CKD), a serious disorder that leads to a prominent reduction in quality of life and might end fatally. Independent of its initial cause, virtually all
Urea is truly toxic: the empire strikes back
Urea is a metabolic waste product that accumulates in the body in the setting of chronic kidney disease. It is routinely measured on blood tests as a marker of kidney function (higher urea levels indicate lower kidney
Electrically controlled insulin release
Stimuli responsive materials are promising for designing the next generation of drug delivery systems. Such materials would enable drugs to be released on-demand or in response to patient needs, specifically at the target site, minimizing side effects.
The journey of Campylobacter: a genomic analysis of a successful zoonotic pathogen
Campylobacter is the leading cause of human gastroenteritis worldwide. Domestic and wild birds are likely zoonotic vectors of Campylobacter. We demonstrated that American crows, abundant in urban, suburban, and agricultural settings, carry multiple Campylobacter genotypes that are
Conformal invariants for landmark curve based brain morphometry analysis
Abnormal structural changes measured on cortical surfaces are important biomarkers for Alzheimer’s disease (AD). In brain imaging research, landmark curves are usually delineated on cortical surfaces to represent significant sulcus and gyrus patterns. Landmark curves are widely
Production and diseases of dairy cows: genetics (cause) and management (effect)
The milk production of dairy cows has been increased during the last decades by animal-husbandry, improved feeding regime, extensive veterinary service and proper management. It can be assumed that this tendency will be continued in the future
Brucellosis, tuberculosis and caprine arthritis-encephalitis, are goats and sheep in El Salvador affected?
Brucellosis and tuberculosis are two animal diseases that occur in Salvadoran cattle and humans may get infected by drinking raw milk. When herds get infected for the first time with brucellosis, massive abortions in the last third
Regional Alzheimer’s disease research
According to World Alzheimer Report 2015, over 46 million people live with dementia worldwide. The incidence of dementia is estimated over 9.9 million every year, and nearly half of new dementia cases (4.9 million) occurred in Asia.
Novel approaches to cancer treatment encoded within non-coding RNA
A hallmark of all living organisms is the presence of genetic material within each cell; this material is invariantly composed of a specific class of biological molecules known as the nucleic acids. While the more familiar variety
Inflammatory bowel disease: one, two, or a thousand diseases
The so-called Inflammatory Bowel Diseases (Ulcerative Colitis –UC- and Crohn’s Disease –CD-, comprised under the umbrella acronym IBD) often come about with the accompaniment of variegated pathologic conditions that are mostly inflammatory in nature. Among them, the
The relationship between clinical and standardised tests for hand-arm vibration syndrome
Hand-arm vibration syndrome (HAVS), previously known as vibration white finger, may be difficult to diagnose. It manifests in two forms – vascular with blanching of the fingers or sensorineural with tingling, numbness and loss of dexterity of
Gorham disease
Gorham disease is a rare condition affecting bones of skeletal system with unknown cause. To our knowledge the number of identified cases worldwide ranges around 300. Gorham and Stout were the first to define this disease back
Heart defects before birth: Why are most cases still being missed (and what can we do about it)
Heart defects occur in roughly 1 in 100 live births—far more than any other kind of birth defect. Over the past decade, it has become increasingly clear that babies with major forms of heart disease have must
Plants versus pathogens: detection and deception
Novel research has unveiled more about the deception tactics used by plants in their continuous battle against attacks from disease-causing pathogens. These findings could help in breeding better crops to reduce losses and produce more food. In
