Tag Archives: pain

Stress must not be confused with pain

Our article “Stress is not pain” was a critique on a study by Elwood & Adams who exposed crabs to electric shocks and concluded that their study ‘. . .fulfils the criteria expected of a pain experience’. 

GlyT2 inhibitors: Getting the balance right

In the central nervous system, signals are sent through brain pathways using neurotransmitters, the chemical messengers of our brain. The strength and duration of these messages are governed by the concentration of neurotransmitters in the synapses between

Older Australians in nursing homes have limited access to complementary medicines for pain relief

In Australia and elsewhere, older people living in the community use complementary medicines (CM) to manage the symptoms of chronic illnesses, especially pain, and to supplement ‘conventional’ medical treatments for the same conditions. The bulk of CM

Benefits of aging?

Does pain increase or decrease with age, and if so, what causes the change?  A factor we considered is that sensitivity to pain could be altered by an age-related loss of neurons involved in regulation of affective/emotional

Do you have pain on the lateral side of your knee (often diagnosed as iliotibial Band Syndrome)?

Runners, bicyclists, and many other active individuals who experience pain along the lateral side of their knee joint are often diagnosed as having iliotibial band syndrome or iliotibial band friction syndrome.  This problem is attributed to a

Glucosamine reduces the need for pain medications in osteoarthritis, but the correct formulation is essential

For osteoarthritis, drugs that can delay disease progression have the potential to reduce the need for additional pain medications. But be careful which drug you chose: this effect is only shown with the prescription patented crystalline glucosamine

Extended VATS lobectomy

A lobectomy is the standard operation for removal of a lung cancer.  Traditionally, it is performed through a large incision (approximately 15 cm or 6 inches) at the side of the chest.  This incision, termed a thoracotomy,

PACAP expression induced in neuropathic pain is controlled by a splicing of REST/NRSF

Neuropathic pain (NP) is caused by the damage of the nervous system and one of the most common types of intractable pain. It is often severe, persistent, and refractory to available therapies. Although various analgesic has been

Controlling pain and symptoms at end-of-life: a better way

The World Health Organization has defined Palliative Care as: “The active total care of patients whose disease is not responsive to curative treatment. The goal… is to achieve the best quality of life for patients and their

Time for a new understanding of chest pain

Most people who present to hospitals with pain in the chest have nothing wrong with their hearts. A small proportion have another physical problem such as acid reflux from the stomach but most have health anxiety or

A simple method for the Study of Acid Sensing Ion Channels (ASICs) by fluorescence

The presence of severe acidosis has been demonstrated to be associated to several pathological conditions, such as multiple sclerosis, brain trauma, spinal cord injury and epilepsy as well as in inflammatory pain, to cite the most relevant.

Rare and uncommon cancers

A rare cancer is one that occurs less than 6 times in 100,000 people and an uncommon cancer is found between 6 and 12 times in each 100,000 people. The problem with being rare is that there

Radiation therapy for nerve pain when cancer spreads to bones

One of the hallmarks of cancer is its ability to spread from the primary site of origin to other places in the body.  Such secondary sites are called “metastases”.  One of the commonest sites for cancer secondaries

A novel platform to measure orthodontic actions

Orthodontics is the medical specialty, where there exists the strongest link between biomechanics and treatment outcome: the application of mechanical tools and instruments to achieve tooth movement and thus correct malocclusions. However, for many clinicians this link

The role of the thalamic submedius nucleus histamine in modulation of formalin-induced orofacial pain

Pain is one of the most common and disturbing of human experiences. While it has many causes, the appreciation of painful sensation depends on the stimulation of pain receptors (nociceptors) and the conduction of the nerve impulses

A disease of younger women

Cramp or pain during menstruation is very common, but telling a young woman that this is ‘normal’ without full assessment can be wrong as this can lead to many years of unnecessary suffering. There are many conditions

How can I create more mobility in my stiff shoulder?

A stiff shoulder, or the so-called “frozen shoulder”, is a disorder characterized by progressive pain and loss of mobility of the shoulder. The annual incidences are 3 to 5% in the general population and even up to

Awful knee pain, rounding up the unusual suspects

If you have had persisting severe knee pain following an arthroscopy you might wonder why. When this happens many people will have a repeated MRI following the surgery despite the fact that one was done before the

Does neuropathic pain restrict the cortical plasticity after spinal cord injury?

Many studies in animals and humans have shown that the brain reacts with some reorganization (called neuro-adaptive processes) to the amputation of limbs and following a spinal cord injury that leaves the patients with severe motor and

The influence of attachment on pain and depression in two different pain groups

Attachment style which can be categorized into secure and insecure can be associated with the development and perception of pain. A secure attachment style is related to people that are able to build a support system by