Author Archives: karen
What’s the point? Cognitive advantage
Neuroscientists have long wondered why some behaviours are mostly controlled by one side of the brain. This phenomenon is called brain lateralization. For centuries we have known that damage to the left but not the right side
The healthy neighborhoods healthy families initiative: A zip code should not determine a child’s health
Published in the journal Pediatrics, researchers from Nationwide Children’s Hospital presented a case study for treating a neighborhood as a patient. Neighborhood effect syndrome, characterized by symptoms of extreme poverty including housing insecurity, racial segregation, trauma, violence,
The difference of an amide to ester in polymers does the magic
Antibiotics kill bacteria by a specific targeting mechanism, and thereby, bacteria quickly develop resistance to antibiotics. The bacterial cell membrane is pivotal to its survival and is considered its Achille’s heel. Killing bacteria by attacking their cell
Why are processed vegetable foodstuffs not as green as raw? Following the fate of chlorophylls
In addition to play an important role in photosynthesis and plant physiology, chlorophylls fulfil certain biological activities. Chlorophylls and their derivatives have been shown to exert antimutagenic and anticarcinogenic activity. In the human diet, these compounds are
Wicherhamomyces anomalus biofilm supported on wood husk for chromium wastewater treatment
Toxic heavy metals are harmful pollutants increasingly discharged in the environment by natural and anthropogenic means. Due to its widespread use in industrial processes, chromium presents a significant impact on the surface waters and ecosystem services. Because
Heart medication and metabolism: What physicians should reflect on to keep them in harmony
Cardiovascular diseases are the leading cause of death globally and have been for a long time. This spotlight has ensured that doctors treating patients with heart problems have a wide variety of medications to work with. Most
Chronic Care Model and multi-morbidity patients. Insights from patients’ perception
More and more countries have been implementing chronic care programs, such as the Chronic Care Model (CCM) to manage non-acute conditions of diseases in a more effective and less expensive way. Among the CCM components there are
Development of a better and cheaper approach for fabrication of epidermal sheets used for wound healing
About 1% of the world population are affected by pressure and diabetic foot ulcers and around 11 million people are injured by thermal burns each year. Cell therapy is a promising therapeutic approach for the treatment of
High phenolic content in extra virgin olive oil influences the release (time-intensity) of aroma compounds in mouth
The popularity of extra virgin olive oil (EVOO) is linked both to its pleasant sensory notes and health properties. The sensory notes of EVOO are attributed to the presence of aroma compounds while bitterness and pungency are
A mass spectrometry view of the interaction of Alzheimer’s disease proteins with an anti-aggregation compound
Alzheimer’s disease is a neurodegenerative disease that has been studied extensively over the last four decades. Millions of people worldwide are affected by this disease, and because our population is growing older, this disease is becoming alarmingly
What do patients and healthcare professionals “tweet” about brachytherapy?
Many patients post on Twitter about their healthcare experiences. Patients with cancer are especially active on Twitter, and studies have found that sharing experiences online can reduce feelings of isolation. Healthcare professionals also frequently post on Twitter.
Unboxing the role of TBX1 in palatal development: a gene profiling study
Cleft palate (CP) is a disease where there is an opening or split in the palate (the roof of the mouth). CP has been reported in 1 to 2 of every 1000 births worldwide and is the
When the obsession with healthy food becomes a problem
Healthy eating is promoted in today’s society as a positive and powerful behaviour to prevent all kinds of diseases. Therefore, making dietary restrictions and following certain food beliefs (vegetarianism, veganism, paleo diet, etc.) are behaviours considered normal
Preparation of various nucleosomes for biochemical and structural analyses
Genomic DNA, which encodes genetic information, is three-dimensionally organized in the cell as chromatin. Its basic unit is the nucleosome, a disc-like structure containing two copies each of histones H2A, H2B, H3, and H4, with DNA wound around
Role of ultrasonography in the evaluation of traumatic injury to peripheral nerves
Traumatic injury of peripheral nerve accounts for about 3-5% of limb trauma, but if not diagnosed it can be associated with negative outcomes, especially in major trauma, with economic and social damage when working-age subjects are involved.
Forward and reverse mutations in stages of cancer development
Mutations in somatic genomes are known to be the basis of cancers, understanding of which is essential for cancer prevention, diagnosis and therapy. In our study, mutations changing the genomic DNA sequences of a cell from its
Production techniques for the development of sub-micron size polymeric drug delivery formulations evaluated
Polymeric drug delivery formulations containing active pharmaceutical ingredients (APIs) offer the advantages of improved stability, targeted delivery and controlled release of APIs in vivo, which can reduce drug burden while enhancing efficacy. Poly(lactic-co-glycolic acid) (PLGA) is amongst
Dramatically distinct tropism and transduction efficiencies of AAV serotypes following subconjunctival injection
Instead of relying on traditional drug modalities, gene therapies rely on delivery of nucleic acids into patient’s cells to prevent, slow, stop or treat diseases. In the past decades, gene therapy has been broadly studied in pre-clinical
Stem cells and stem cells conditioned medium for inflammatory bowel disease treatment
Inflammatory bowel disease (IBD) is a complex of pathological processes occurring in the intestine. Chemically induced IBD in rodent usually used for study of drug therapy efficacy. Mesenchymal stem cells (MSC) was used as alternative method for
FLYWCH1 is a novel transcriptional repressor for the cancer-causing Beta-catenin
There is no doubt that cancer is a devastating disease. However, restraining the cancerous cells from spreading throughout the body (invasion) will make it easier to control and possibly cure cancer. β-catenin is one of the proteins
