Tag Archives: diabetes
Long-term outcome in patients admitted with a heart attack and detected with increased blood sugar levels during admission
An Oral Glucose Tolerance Test ( OGTT ) is one of the diagnostic tests to determine the presence of pre – diabetes or manifest diabetes. An OGTT involves drinking a 75 gram sugar solution after 8 hours
Can you reduce your risk of diabetes with lifestyle changes?
Glucose homeostasis deficiency may lead to chronic increase in blood glucose levels and could affect a large number of tissues and organs. The shift from early metabolic abnormalities that forego diabetes, such as impaired fasting glucose and
Optimizing diabetes care on a global scale
Diabetes is a major threat to healthy living for hundreds of millions of people worldwide. Type-1 diabetes must be treated with insulin and type-2 diabetes (the more common form) can be treated with lifestyle changes, oral medication,
AMPK: How can we amp it up to fight disease?
The high prevalence of obesity, insulin resistance, type 2 diabetes and cardiovascular disease has made it clear that we need a better understanding of how our bodies store and use energy when we overload them with excess
Active role of cell-derived microparticles in diabetes associated cardiovascular complications
Diabetes mellitus is a metabolic disorder characterized by high blood glucose (or hyperglycaemia) resulting from defects in insulin secretion from the pancreatic beta cells, insulin action, or both. The chronic hyperglycaemia produces disturbances of carbohydrate, fat and
Insulin analogue with reduced weight gain effect in diabetic patients: detemir
Diabetes mellitus is a progressive condition in which the glycated hemoglobin level (i.e. marker of average blood glucose levels) rises inexorably over time. Strict glucose control in patients with type 1 or type 2 diabetes mellitus reduces
Statins and diabetes: do the benefits outweigh the risks?
Cardiovascular disease (heart attack and stroke) is the leading cause of death in the United States. Prescription cholesterol-lowering medications have been shown to lower the risks for heart attacks and stroke. In fact, roughly 28% of Americans
Can antioxidants benefit the diabetic kidney?
People who have diabetes are at high risk of developing kidney disease that may require dialysis or transplantation. This has been known for a long time but there is still a need for new ways to prevent
New advances in the classification of diabetes beyond type 1 and 2: monogenic diabetes
The classification of diabetes has become increasingly complex in recent years, particularly in young patients, and now goes beyond the traditional forms of type 1 and type 2 diabetes. Type 1 diabetes, which is linked to the
A better way to measure heart disease risk for an overweight society
Low density lipoprotein (LDL) cholesterol or the “bad cholesterol” is an established measure of cardiovascular risk. LDL particles interact with the lining of the blood vessel and contribute to cholesterol loading in the arterial wall. Continued buildup
The earlier, the better and the controlled. Glucose level sensing in diabetic patients through nano biosensors
Gone are the days when there was a big pain for patients suffering from high blood glucose (blood sugar) level that early and rapid detection was a long wait & rather unpleasant. Now recently developed approaches using
A new drug target for healthful aging
With the aging population of the United States increasing every year, there is an increasing need to develop new therapeutic modalities to provide for healthful aging. Although longevity is generally considered positively in most families, and of
Poor blood sugar control in elderly people with diabetes is associated with increased infection risk
Diabetes guidelines for doctors (such as those by NICE) suggest that they consider relaxing the blood sugar control targets for older people. This is because older people are less likely to get the long-term benefits of improved
Prox-1 and adipogenesis
Adipogenesis is the biological process that controls adipocytes differentiation and is one of the most well studied models of cellular differentiation. Adipose tissue is involved in the control of energy balance and especially in the study of
Silencing a microRNA may keep the doctor away for diabetic wounds
Patients with diabetes are frequently afflicted with impaired wound healing that may progress into chronic, diabetic ulcers, often leading to complications including limb amputation with increased risk of morbidity and mortality. These ulcers occur not only in
Alternative splicing: the new frontier in diabetes research
The human genome is predicted to contain 22.000 coding genes, but more than 200.000 proteins are expressed in human cells. This discrepancy is explained at least in part by the presence of alternative splicing (AS), a key
Food and Nutrition cause liver and brain diseases with diabetes in the developing and developed world
In the world the consumption of a healthy diet is essential to prevent diseases such as obesity, diabetes and brain diseases. New discoveries in medicine indicate that a diet that is low in fat and carbohydrate lower
Disguising insulin as an antibody: a Trojan horse for type 1 diabetes prevention
Type 1 Diabetes (T1D) is an auto-immune disease. These diseases appear when our own immune system, which normally protects us from foreign pathogens (viruses, bacteria,…), attacks our own cells. In the case of T1D, T lymphocytes, which
Alzheimer’s disease or type 2 diabetes?
Alzheimer’s disease (AD) is one of the most common causes of senile dementia and it is estimated that by 2050, the number of cases will rise to 110 million. The vast majority of patients suffer from the
Exorcising autoimmunity
Moderately intense physical exercise, performed at regular intervals, is now firmly recognized as a safe and effective intervention by which to enhance quality of life. Despite this awareness, for many of us, as our age increases, so
